Lamotrigine: Clinical experience in 200 patients with epilepsy with follow-up to four years

Seizure

Volumn 5, Issue 3, 1996, Pages 209-214

  Buchanan, Neil ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b NONE   (Australia)

Author keywords

Lamotrigine; Seizure control; Side effects

Indexed keywords

ACETAZOLAMIDE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; DIAZEPAM; ETHOSUXIMIDE; FELBAMATE; LAMOTRIGINE; METHYLPHENOBARBITAL; NITRAZEPAM; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID; VIGABATRIN;

ADOLESCENT; ADULT; AGED; AGITATION; ANTICONVULSANT THERAPY; ARTICLE; BRAIN INJURY; CAREGIVER; CHILD; CLINICAL TRIAL; COMPLEX PARTIAL SEIZURE; DRUG EFFICACY; EPILEPSY; GENERALIZED EPILEPSY; HEADACHE; HUMAN; INSOMNIA; LENNOX GASTAUT SYNDROME; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITY OF LIFE; RASH; SCHOOL CHILD; SEIZURE; TONIC CLONIC SEIZURE; TONIC SEIZURE; TREMOR; VERTIGO;

EID: 0029857729     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1059-1311(96)80038-0     Document Type: Article

References (32)

1. Richens, A. Lamotrigine in epilepsy. London, Churchill Livingstone, 1992: pp. 197-210.
2. Brodie, M.J. Lamotrigine. Lancet 1992; 339: 1397-1400.
3. Betts, T. Clinical use of lamotrigine. Seizure 1992, 1: 3-6.
4. Goa, K.L., Ross, S.R. and Chrisp, P. Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1993; 46: 152-176.
5. Timmings, P.L. and Richens, A. Lamotrigine in primary generalized epilepsy. Lancet 1992; 339: 1300-1301.
6. Sanders, J.W.S., Hart, Y.M. and Patsalos, P.N. et al. Lamotrigine and generalized seizures. Epilepsia 1991; 32 (Suppl. 1): 59.
7. Stewart, J., Hughes, E. and Reynolds, E.H. Lamotrigine for generalised epilepsies. Lancet 1992; 340: 1223.
8. Oller, L.F.V., Russi, A. and Oiler Daurella, L. Lamotrigine in the Lennox Gastaut syndrome. Epilepsia 1991; 32 (Suppl. 1): 58.
9. Schlumberger, E., Chavez, F., Dulac, O. and Moszkowski, J. Open study with lamotrigine (LTG) in childhood epilepsy. Seizure 1992; 1 (Suppl. A): 9-21.
10. Timmings, P.L. and Richens, A. Lamotrigine as an add-on drug m the management of Lennox Gastaut syndrome. European Neurology 1992; 32: 305-307.
11. Yuen, A.W.C. and Rafter, J.E.W. Lamotrigine (Lamictal) as add-on therapy in paediatric patients with treatment-resistant epilepsy. An overview. Epilepsia 1992; 33 (Suppl. 3): 82-83.
12. Gibbs, J., Appleton, R.E., Rosenbloom, L. and Yuen, A.W.C. Lamotrigine for intractable childhood epilepsy: a preliminary communication. Developmental Medical Child Neurology 1992; 34: 368-371.
13. Wallace, S.J. Add-on open trial of lamotrigine in resistant childhood seizures. Brain Development 1990; 12: 734.
14. Binnie, C.D., Vam Emde Boas, W., Kesteleijn-Nolste-Trenite, D.G.A. et al. Acute effects of lamotrigine (BW 430C) in persons with epilepsy. Epilepsia 1986; 27: 248-254.
15. Yuen, A.W.C., Land, G., Weatherby, B.C. and Peck, A.W. Sodium valproate acutely inhibits lamotrigine metabolism. British Journal of Clinical Pharmacology 1992; 33: 511-513.
16. Smith, D., Baker, G., Davies, G., Dewey, M. and Chadwick, D.W. Outcomes of add-on treatment with lamotrigine in partial epilepsy. Epilepsia 1993; 34: 312-322.
17. Sander, J.W.A.S., Patsalos, P.N., Oxley, J.R., Hamilton, M.J. and Yuen, W.C. A randomised double-blind placebo-controlled add-on trial of lamotrigine in patients with severe epilepsy. Epilepsy Research 1990; 6: 221-226.
18. Schapel, G.J., Heran, R.G., Vadja, E.J.E. et al. Double blind, placebo controlled, crossover study of lamotrigine in treatment resistant partial seizures. Journal of Neurological Neurosurgical Psychiatry 1993; 56: 448-453.
19. Vogt, H., Lazarevic, G., Scalabrin, P., Zwiefel, V. and Kramer, G. Lamotrigine add-on therapy in 76 adult patients with refractory generalised epilepsies. Epilepsia 1994; 35 (Suppl. 7): 71.
20. Manomani, V. and Wallace, S.J. Epilepsy with myoclonic absences. Archives of Diseases of Childhood 1994; 70: 288-290.
21. Ferrie, C.D., Robinson, R.O., Knott, C. and Panayiotopoulos, C.P. Lamotrigine as an add-on drug in typical absence seizures. Acta Neurological Scandinavia 1995; 91: 200-202.
22. Buchanan, N. Lamotrigine: clinical experience in 93 patients with epilepsy. Acta Neurologica Scandinavica 1995; 92: 28-32.
23. Buchanan, N. Lamotrigine in juvenile myoclonic epilepsy. 1996; 5: 149-151.
24. Timmings, P.L. and Richens, A. Efficacy of lamotrigine as monotherapy for juvenile myoclonic epilepsy: pilot studyresults. Epilepsia 1993; 34 (Suppl. 2): 160.
25. Schlumberger, E., Chavez, F., Palacios, L., Key, E., Pajot, N. and Dulac, O. Lamotrigine in treatment of 120 children with epilepsy. Epilepsia 1994; 35: 359-367.
26. Chevalier, Y., Grinspan, A., Hirsch, E., Moszkowski, J. and Marescaux, C. Lamotrigine in Lennox-Gastaut Syndrome: an EEG study. Epliepsia 1994; 35 (Suppl. 8): 96.
27. Buchanan, N. Lamotrigine use in 12 patients with the Lennox-Gastaut syndrome. European Journal of Neurology 1995; 2: 501-503.
28. Buchanan, N. The efficacy of lamotrigine on seizure control in 34 children, adolescents and young adults with intellectual and physical disability. Seizure 1995; 4: 233-236.
29. Canadian Clobazam Co-operative Group. Clobazam in treatment of refractory epilepsy: the Canadian experience. A retrospective Study. Epilepsia 1991; 32: 407-416.
30. Buchanan, N. Clobazam in the treatment of epilepsy: prospective follow-up to 8 years. Journal of the Royal Society of Medicine 1993; 86: 378-380.
31. Buchanan, N. Vigabatrin use in 72 patients with drug resistant epilepsy. Seizure 1994; 3: 191-196.
32. Reynolds, E.H. Gamma-vinyl GABA (Vigabatrin): clinical experience in adult and adolescent patients with intractable epilepsy. Epilepsia 1992; 33 (Suppl. 5): S30-S35.