메뉴 건너뛰기




Volumn 40, Issue 6, 1999, Pages 769-776

Quantification in patient urine samples of felbamate and three metabolites: Acid carbamate and two mercapturic acids

Author keywords

Atropaldehyde; Felbamate; Mercapturate; Metabolite; Toxicity

Indexed keywords

3 CARBAMOYL 2 PHENYLPROPIONALDEHYDE; ACETYLCYSTEINE; ACETYLCYSTEINE DERIVATIVE; CARBAMIC ACID DERIVATIVE; FELBAMATE; N D3 ACETYL S (2 PHENYLPROPAN 3 OLYL)CYSTEINE; N D3 ACETYL S CYSTEINYL 2 PHENYLPROPANOIC ACID; UNCLASSIFIED DRUG;

EID: 0033012622     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1999.tb00777.x     Document Type: Article
Times cited : (59)

References (19)
  • 1
    • 0029967781 scopus 로고    scopus 로고
    • New drugs for the treatment of epilepsy
    • Fraser AD. New drugs for the treatment of epilepsy. Clin Biochem 1996;29:97-110.
    • (1996) Clin Biochem , vol.29 , pp. 97-110
    • Fraser, A.D.1
  • 2
    • 0029985419 scopus 로고    scopus 로고
    • Diagnosis and treatment of epilepsy in children and adolescents
    • Brodie MJ, Pellock JM. Diagnosis and treatment of epilepsy in children and adolescents. Drugs 1996;51:399-414.
    • (1996) Drugs , vol.51 , pp. 399-414
    • Brodie, M.J.1    Pellock, J.M.2
  • 3
    • 0027223706 scopus 로고
    • Comparative pharmacokinetics of the newer antiepileptic drugs
    • Bialer M. Comparative pharmacokinetics of the newer antiepileptic drugs, Clin Pharmacokinet 1993;24:441-52.
    • (1993) Clin Pharmacokinet , vol.24 , pp. 441-452
    • Bialer, M.1
  • 4
    • 0022627469 scopus 로고
    • Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats
    • Swinyard EA, Sofia RD, Kupferberg HJ. Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats. Epilepsia 1986;27:27-34.
    • (1986) Epilepsia , vol.27 , pp. 27-34
    • Swinyard, E.A.1    Sofia, R.D.2    Kupferberg, H.J.3
  • 5
    • 0029055770 scopus 로고
    • Aplastic anemia in a patient receiving felbamate for complex partial seizures
    • Pennell PB, Ogaily MS, Macdonald RL. Aplastic anemia in a patient receiving felbamate for complex partial seizures. Neurology 1995;45:456-60.
    • (1995) Neurology , vol.45 , pp. 456-460
    • Pennell, P.B.1    Ogaily, M.S.2    Macdonald, R.L.3
  • 7
    • 0028765656 scopus 로고
    • From the Food and Drag Administration: Recommendation to immediately withdraw patients from treatment with felbamate
    • Nightingale SL. From the Food and Drag Administration: recommendation to immediately withdraw patients from treatment with felbamate. JAMA 1994;272:995.
    • (1994) JAMA , vol.272 , pp. 995
    • Nightingale, S.L.1
  • 8
    • 0029849184 scopus 로고    scopus 로고
    • Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: Putative reactive metabolites of felbamate
    • Thompson CD, Kinter MT, Macdonald TL. Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: putative reactive metabolites of felbamate. Chem Res Toxicol 1996;9:1225-9.
    • (1996) Chem Res Toxicol , vol.9 , pp. 1225-1229
    • Thompson, C.D.1    Kinter, M.T.2    Macdonald, T.L.3
  • 9
    • 0030975561 scopus 로고    scopus 로고
    • Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration
    • Thompson CD, Gulden PH, Macdonald TL. Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration. Chem Res Toxicol 1997;10:457-62.
    • (1997) Chem Res Toxicol , vol.10 , pp. 457-462
    • Thompson, C.D.1    Gulden, P.H.2    Macdonald, T.L.3
  • 10
    • 0027275692 scopus 로고
    • Isolation and identification of 3-carbamoyloxy-2-phenylpropionic acid as a major human urinary metabolite of felbamate
    • Adusumalli VE, Choi YM, Romanyshyn LA, et al. Isolation and identification of 3-carbamoyloxy-2-phenylpropionic acid as a major human urinary metabolite of felbamate. Drug Metab Dispos 1993;21:710-6.
    • (1993) Drug Metab Dispos , vol.21 , pp. 710-716
    • Adusumalli, V.E.1    Choi, Y.M.2    Romanyshyn, L.A.3
  • 13
    • 0030459693 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatotoxicity. Analysis of total covalent binding vs. specific binding to cysteine
    • Matthews AM, Roberts DW, Hinson JA, Pumford NR. Acetaminophen-induced hepatotoxicity. Analysis of total covalent binding vs. specific binding to cysteine. Drug Metab Dispos 1996;24: 1192-6.
    • (1996) Drug Metab Dispos , vol.24 , pp. 1192-1196
    • Matthews, A.M.1    Roberts, D.W.2    Hinson, J.A.3    Pumford, N.R.4
  • 14
    • 0020325715 scopus 로고
    • Metabolic activation and drug toxicity
    • Nelson SD. Metabolic activation and drug toxicity. J Med Chem 1982;25:753-65.
    • (1982) J Med Chem , vol.25 , pp. 753-765
    • Nelson, S.D.1
  • 15
    • 0026546128 scopus 로고
    • The mechanism of bioactivation and antigen formation of amodiaquine in the rat
    • Harrison AC, Kitteringham NR, Clarke JB, Park BK. The mechanism of bioactivation and antigen formation of amodiaquine in the rat. Biochem Pharmacol 1992;43:1421-30.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1421-1430
    • Harrison, A.C.1    Kitteringham, N.R.2    Clarke, J.B.3    Park, B.K.4
  • 16
    • 0029909785 scopus 로고    scopus 로고
    • Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis
    • Bourdi M, Chen W, Peter RM, et al. Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis. Chem Res Toxicol 1996;9:1159-66.
    • (1996) Chem Res Toxicol , vol.9 , pp. 1159-1166
    • Bourdi, M.1    Chen, W.2    Peter, R.M.3
  • 17
    • 0029786269 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis
    • Eliasson E, Kenna JG. Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis. Mol Pharmacol 1996;50:573-82.
    • (1996) Mol Pharmacol , vol.50 , pp. 573-582
    • Eliasson, E.1    Kenna, J.G.2
  • 18
    • 0030827761 scopus 로고    scopus 로고
    • A proposed mechanism for p-aminoclonidine allergenicity based on its relative oxidative lability
    • Thompson CD, Vachaspati PR, Kolis SP, et al. A proposed mechanism for p-aminoclonidine allergenicity based on its relative oxidative lability. Chem Res Toxicol 1997;10:1032-6.
    • (1997) Chem Res Toxicol , vol.10 , pp. 1032-1036
    • Thompson, C.D.1    Vachaspati, P.R.2    Kolis, S.P.3
  • 19
    • 0031564619 scopus 로고    scopus 로고
    • Current trends in drug-induced autoimmunity
    • Uetrecht JP. Current trends in drug-induced autoimmunity. Toxicology 1997;119:37-43.
    • (1997) Toxicology , vol.119 , pp. 37-43
    • Uetrecht, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.