Cross sensitivity of skin rashes with antiepileptic drugs

Canadian Journal of Neurological Sciences

Volumn 24, Issue 3, 1997, Pages 245-249

  Hyson, Chris ^a,b   Sadler, Mark ^b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b QUEEN ELIZABETH II HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; ETHOSUXIMIDE; GABAPENTIN; LAMOTRIGINE; MESUXIMIDE; NITRAZEPAM; PHENOBARBITAL; PHENYTOIN; PRIMIDONE; TRIMETHADIONE; VALPROIC ACID; VIGABATRIN;

ARTICLE; CROSS ALLERGY; EPILEPSY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RASH;

EID: 0030801150     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0317167100021880     Document Type: Article

References (24)

1. Chadwick D, Shaw MBM, Foy P, Rawlins MD, Turnbull DM. Serum anticonvulsant concentrations and the risk of drug induced skin eruptions. J Neurol Neurosurg Psychiatry 1984; 47: 642-644.
2. Richens A, Davidson DL, Cartlidge NE, Easter DJ. A multicentre comparative trial of sodium valproate and carbamazepine in adult onset epilepsy. J Neurol Neurosurg Psychiatry 1994; 57: 682-687.
3. Brodie MJ, Richens A, Yuen AWC. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet 1995; 345: 476-479.
4. Sillanpaa M. Carbamazepine: pharmacology and clinical uses. Acta Neurol Scand 1981; 64 (Suppl. 88): 1-102.
5. Kramlinger KG, Phillips KA, Post RM. Rash complicating carbamazepine therapy. J Clin Psychopharmacol 1994; 14: 408-413.
6. Mattson RH, Cramer J, Collins JF. A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. N Engl J Med 1992; 327: 765-771.
7. Knutsen AP, Anderson J, Satayaviboon S, Slavin RG. Immunologie aspects of phénobarbital hypersensitivity. J Pediatr 1984; 105: 558-563.
8. Dreifuss FE, Langer DH. Side effects of valproate. Am J Med 1988; 84 (Suppl. 1): 34-41.
9. Roujeau JC, Sterns RS. Severe adverse cutaneous reactions to drugs. N Engl J Med 1994; 331: 1272-1278.
10. Pelekanos J, Camfield P, Camfield C, Gordon K. Allergic rash due to antiepileptic drugs: clinical features and management. Epilepsia 1991; 32: 544-559.
11. Dean AG, Dean JA, Burton AH, Dicker RC. Epi Info: a general purpose microcomputer program for public health information systems. Am J Prev Med 1991; 7: 178-182.
12. Shear N, Spielberg SP. Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk. J Clin Invest 1988; 82: 1826-1832.
13. Kahn HD, Faguet GB, Agée JF, Middleton HM. Drug induced liver injury. In vitro demonstration of hypersensitivity to both phenytoin and phénobarbital. Arch Intern Med 1984; 144: 1677-1679.
14. Goldstein N, Leider M, Baer R. Drug eruptions from anticonvulsant drugs. Arch Dermatol 1963; 87: 612-617.
15. Reents SB, Luginbuhl WE, Davis SM. Phenytoin-carbamazepine cross-sensitivity. DICP 1989; 23: 235-236.
16. Pirmohamed M, Graham A, Roberts P, et al. Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross reactivity with phenytoin and oxcarbazepine. Br J Pharmac 1991:32:741-749.
17. Chang DKM, Shear NH. Cutaneous reactions to anticonvulsants. Semin Neurol 1992; 12: 329-337.
18. Richens A. Safety of lamotrigine. Epilepsia 1994; 35 (Suppl. 5): S37-S40.
19. Smith H, Newton R. Adverse reactions to carbamazepine managed by desensitization (Letter). Lancet 1985; 1: 753.
20. Eames P. Adverse reactions to carbamazepine managed by desensitization (Letter) Lancet 1989; 1:509-510.
21. Tavernor SJ, Wong 1C, Newton R, Brown SW. Rechallenge with lamotrigine after initial rash. Seizure 1995; 4: 67-71.
22. Heller AJ, Chesterman P, Elwes RDC, et al. Phenobarbïtone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial. J Neurol Neurosurg Psychiatry 1995; 58: 44-50.
23. Mclean MJ. Gabapentin. Epilepsia 1995; 36 (Suppl. 2): S73-S86.
24. Ben-Menachem E. Vigabatrin. Epilepsia 1995; 36 (Suppl. 2): S95-S104.