메뉴 건너뛰기




Volumn 8, Issue 10, 2012, Pages 1510-1520

Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage

Author keywords

Atg7; Autophagic cell death; Cerebral hemorrhage; Estradiol; Estrogen receptor; Iron induced brain injury; Macroautophagy

Indexed keywords

DOPAMINE 2 RECEPTOR; ESTRADIOL BENZOATE; ESTROGEN RECEPTOR; FERROUS CITRATE FE 59; IRON; RAPAMYCIN; SMALL INTERFERING RNA;

EID: 84867250358     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.21289     Document Type: Article
Times cited : (57)

References (27)
  • 1
    • 33846639223 scopus 로고    scopus 로고
    • Brain injury after intracerebral hemorrhage: The role of thrombin and iron
    • PMID:17261733
    • Hua Y, Keep RF, Hoff JT, Xi G. Brain injury after intracerebral hemorrhage: the role of thrombin and iron. Stroke 2007; 38(Suppl):759-62; PMID:17261733; http://dx.doi.org/10.1161/01.STR.0000247868.97078.10
    • (2007) Stroke , vol.38 , Issue.SUPPL. , pp. 759-762
    • Hua, Y.1    Keep, R.F.2    Hoff, J.T.3    Xi, G.4
  • 2
    • 29044441975 scopus 로고    scopus 로고
    • Mechanisms of brain injury after intracerebral haemorrhage
    • PMID:16361023
    • Xi G, Keep RF, Hoff JT. Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 2006; 5:53-63; PMID:16361023; http://dx.doi.org/10. 1016/S1474-4422(05)70283-0
    • (2006) Lancet Neurol , vol.5 , pp. 53-63
    • Xi, G.1    Keep, R.F.2    Hoff, J.T.3
  • 3
    • 70350540901 scopus 로고    scopus 로고
    • Three-year survival and stroke recurrence rates in patients with primary intracerebral hemorrhage
    • PMID:19729603
    • Zia E, Engström G, Svensson PJ, Norrving B, Pessah-Rasmussen H. Three-year survival and stroke recurrence rates in patients with primary intracerebral hemorrhage. Stroke 2009; 40:3567-73; PMID:19729603; http://dx.doi.org/10.1161/STROKEAHA.109.556324
    • (2009) Stroke , vol.40 , pp. 3567-3573
    • Zia, E.1    Engström, G.2    Svensson, P.J.3    Norrving, B.4    Pessah-Rasmussen, H.5
  • 4
    • 76249112303 scopus 로고    scopus 로고
    • Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: A systematic review and meta-analysis
    • PMID:20056489
    • van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 2010; 9:167-76; PMID:20056489; http://dx.doi.org/ 10.1016/S1474-4422(09)70340-0
    • (2010) Lancet Neurol , vol.9 , pp. 167-176
    • Van Asch, C.J.1    Luitse, M.J.2    Rinkel, G.J.3    Van Der Tweel, I.4    Algra, A.5    Klijn, C.J.6
  • 5
    • 2342528946 scopus 로고    scopus 로고
    • Intracerebral hemorrhage in mice: Model characterization and application for genetically modified mice
    • PMID:15129180
    • Nakamura T, Xi G, Hua Y, Schallert T, Hoff JT, Keep RF. Intracerebral hemorrhage in mice: model characterization and application for genetically modified mice. J Cereb Blood Flow Metab 2004; 24:487-94; PMID:15129180; http://dx.doi.org/10.1097/00004647-200405000-00002
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 487-494
    • Nakamura, T.1    Xi, G.2    Hua, Y.3    Schallert, T.4    Hoff, J.T.5    Keep, R.F.6
  • 6
    • 12844256485 scopus 로고    scopus 로고
    • 17beta-Estradiol pretreatment reduces bleeding and brain injury after intracerebral hemorrhagic stroke in male rats
    • PMID:15678126
    • Auriat A, Plahta WC, McGie SC, Yan R, Colbourne F. 17beta-Estradiol pretreatment reduces bleeding and brain injury after intracerebral hemorrhagic stroke in male rats. J Cereb Blood Flow Metab 2005; 25:247-56; PMID:15678126; http://dx.doi.org/10.1038/sj.jcbfm.9600026
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 247-256
    • Auriat, A.1    Plahta, W.C.2    McGie, S.C.3    Yan, R.4    Colbourne, F.5
  • 7
    • 74049161198 scopus 로고    scopus 로고
    • Sex-specific role of thioredoxin in neuroprotection against iron-induced brain injury conferred by estradiol
    • PMID:19940280
    • Chen TY, Tsai KL, Lee TY, Chiueh CC, Lee WS, Hsu C. Sex-specific role of thioredoxin in neuroprotection against iron-induced brain injury conferred by estradiol. Stroke 2010; 41:160-5; PMID:19940280; http://dx.doi.org/10.1161/ STROKEAHA.109.562850
    • (2010) Stroke , vol.41 , pp. 160-165
    • Chen, T.Y.1    Tsai, K.L.2    Lee, T.Y.3    Chiueh, C.C.4    Lee, W.S.5    Hsu, C.6
  • 8
    • 0347626252 scopus 로고    scopus 로고
    • Autophagy: A regulated bulk degradation process inside cells
    • PMID:14684184
    • Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004; 313:453-8; PMID:14684184; http://dx.doi.org/10.1016/j.bbrc.2003.07.023
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 453-458
    • Yoshimori, T.1
  • 9
    • 42549126839 scopus 로고    scopus 로고
    • Autophagy after experimental intracerebral hemorrhage
    • PMID:17987045
    • He Y, Wan S, Hua Y, Keep RF, Xi G. Autophagy after experimental intracerebral hemorrhage. J Cereb Blood Flow Metab 2008; 28:897-905; PMID:17987045; http://dx.doi.org/10.1038/sj.jcbfm.9600578
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 897-905
    • He, Y.1    Wan, S.2    Hua, Y.3    Keep, R.F.4    Xi, G.5
  • 10
    • 6344256753 scopus 로고    scopus 로고
    • mTOR: A protein kinase switching between life and death
    • PMID:15501691
    • Asnaghi L, Bruno P, Priulla M, Nicolin A. mTOR: a protein kinase switching between life and death. Pharmacol Res 2004; 50:545-9; PMID:15501691; http://dx.doi.org/10.1016/j.phrs.2004.03.007
    • (2004) Pharmacol Res , vol.50 , pp. 545-549
    • Asnaghi, L.1    Bruno, P.2    Priulla, M.3    Nicolin, A.4
  • 11
    • 70449397081 scopus 로고    scopus 로고
    • Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation
    • PMID:19889994
    • Zhang QG, Raz L, Wang R, Han D, De Sevilla L, Yang F, et al. Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. J Neurosci 2009; 29:13823-36; PMID:19889994; http://dx.doi.org/10.1523/JNEUROSCI.3574-09.2009
    • (2009) J Neurosci , vol.29 , pp. 13823-13836
    • Zhang, Q.G.1    Raz, L.2    Wang, R.3    Han, D.4    De Sevilla, L.5    Yang, F.6
  • 12
    • 33750302398 scopus 로고    scopus 로고
    • Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain
    • PMID:17018601
    • Yu J, Henske EP. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain. Cancer Res 2006; 66:9461-6; PMID:17018601; http://dx.doi.org/10.1158/ 0008-5472.CAN-06-1895
    • (2006) Cancer Res , vol.66 , pp. 9461-9466
    • Yu, J.1    Henske, E.P.2
  • 13
    • 67650707926 scopus 로고    scopus 로고
    • Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest
    • PMID:19632410
    • Weiss ES, Wang KK, Allen JG, Blue ME, Nwakanma LU, Liu MC, et al. Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest. Ann Thorac Surg 2009; 88:543-50; PMID:19632410; http://dx.doi.org/10.1016/j.athoracsur.2009.04.016
    • (2009) Ann Thorac Surg , vol.88 , pp. 543-550
    • Weiss, E.S.1    Wang, K.K.2    Allen, J.G.3    Blue, M.E.4    Nwakanma, L.U.5    Liu, M.C.6
  • 15
    • 39549093998 scopus 로고    scopus 로고
    • Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury
    • PMID:18187572
    • Koike M, Shibata M, Tadakoshi M, Gotoh K, Komatsu M, Waguri S, et al. Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol 2008; 172:454-69; PMID:18187572; http://dx.doi.org/10.2353/ajpath.2008.070876
    • (2008) Am J Pathol , vol.172 , pp. 454-469
    • Koike, M.1    Shibata, M.2    Tadakoshi, M.3    Gotoh, K.4    Komatsu, M.5    Waguri, S.6
  • 16
    • 72849127046 scopus 로고    scopus 로고
    • A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death
    • PMID:19878437
    • Choi KC, Kim SH, Ha JY, Kim ST, Son JH. A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death. J Neurochem 2010; 112:366-76; PMID:19878437; http://dx.doi.org/10.1111/j.1471-4159.2009.06463.x
    • (2010) J Neurochem , vol.112 , pp. 366-376
    • Choi, K.C.1    Kim, S.H.2    Ha, J.Y.3    Kim, S.T.4    Son, J.H.5
  • 17
    • 56349126024 scopus 로고    scopus 로고
    • Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
    • PMID:18760364
    • Carloni S, Buonocore G, Balduini W. Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol Dis 2008; 32:329-39; PMID:18760364; http://dx.doi.org/10.1016/j.nbd.2008.07.022
    • (2008) Neurobiol Dis , vol.32 , pp. 329-339
    • Carloni, S.1    Buonocore, G.2    Balduini, W.3
  • 18
    • 58149483522 scopus 로고    scopus 로고
    • Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death
    • PMID:18948195
    • Kanno H, Ozawa H, Sekiguchi A, Itoi E. Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death. Neurobiol Dis 2009; 33:143-8; PMID:18948195; http://dx.doi.org/10.1016/j.nbd.2008.09.009
    • (2009) Neurobiol Dis , vol.33 , pp. 143-148
    • Kanno, H.1    Ozawa, H.2    Sekiguchi, A.3    Itoi, E.4
  • 19
    • 0034128362 scopus 로고    scopus 로고
    • Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone
    • PMID:10833057
    • Roof RL, Hall ED. Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone. J Neurotrauma 2000; 17:367-88; PMID:10833057; http://dx.doi.org/10.1089/neu.2000.17.367
    • (2000) J Neurotrauma , vol.17 , pp. 367-388
    • Roof, R.L.1    Hall, E.D.2
  • 20
    • 24944447936 scopus 로고    scopus 로고
    • Estrogen therapy for experimental intracerebral hemorrhage in rats
    • PMID:16121980
    • Nakamura T, Hua Y, Keep RF, Park JW, Xi G, Hoff JT. Estrogen therapy for experimental intracerebral hemorrhage in rats. J Neurosurg 2005; 103:97-103; PMID:16121980; http://dx.doi.org/10.3171/jns.2005.103.1.0097
    • (2005) J Neurosurg , vol.103 , pp. 97-103
    • Nakamura, T.1    Hua, Y.2    Keep, R.F.3    Park, J.W.4    Xi, G.5    Hoff, J.T.6
  • 21
    • 85061108784 scopus 로고    scopus 로고
    • Estrogen reduces iron-mediated brain edema and neuronal death
    • PMID:19812941
    • Gu Y, Xi G, Liu W, Keep RF, Hua Y. Estrogen reduces iron-mediated brain edema and neuronal death. Acta Neurochir Suppl 2010; 106:159-62; PMID:19812941; http://dx.doi.org/10.1007/978-3-211-98811-4-29
    • (2010) Acta Neurochir Suppl , vol.106 , pp. 159-162
    • Gu, Y.1    Xi, G.2    Liu, W.3    Keep, R.F.4    Hua, Y.5
  • 22
    • 4644305774 scopus 로고    scopus 로고
    • Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway
    • PMID:15234982
    • Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, et al. Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem 2004; 279:38563-70; PMID:15234982; http://dx.doi.org/10. 1074/jbc.M405461200
    • (2004) J Biol Chem , vol.279 , pp. 38563-38570
    • Du, L.1    Bayir, H.2    Lai, Y.3    Zhang, X.4    Kochanek, P.M.5    Watkins, S.C.6
  • 23
    • 59049084055 scopus 로고    scopus 로고
    • Starving neurons show sex difference in autophagy
    • PMID:19036730
    • Du L, Hickey RW, Bayir H, Watkins SC, Tyurin VA, Guo F, et al. Starving neurons show sex difference in autophagy. J Biol Chem 2009; 284:2383-96; PMID:19036730; http://dx.doi.org/10.1074/jbc.M804396200
    • (2009) J Biol Chem , vol.284 , pp. 2383-2396
    • Du, L.1    Hickey, R.W.2    Bayir, H.3    Watkins, S.C.4    Tyurin, V.A.5    Guo, F.6
  • 24
    • 0035239031 scopus 로고    scopus 로고
    • Neuroprotection by estradiol
    • PMID:11040417
    • Garcia-Segura LM, Azcoitia I, DonCarlos LL. Neuroprotection by estradiol. Prog Neurobiol 2001; 63:29-60; PMID:11040417; http://dx.doi.org/10.1016/S0301- 0082(00)00025-3
    • (2001) Prog Neurobiol , vol.63 , pp. 29-60
    • Garcia-Segura, L.M.1    Azcoitia, I.2    DonCarlos, L.L.3
  • 25
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
    • PMID:15131264
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304:1500-2; PMID:15131264; http://dx.doi.org/10.1126/science.1096645
    • (2004) Science , vol.304 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6
  • 26
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • PMID:17611390
    • Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007; 3:542-5; PMID:17611390
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 27
    • 0036791849 scopus 로고    scopus 로고
    • Behavioral tests after intracerebral hemorrhage in the rat
    • PMID:12364741
    • Hua Y, Schallert T, Keep RF, Wu J, Hoff JT, Xi G. Behavioral tests after intracerebral hemorrhage in the rat. Stroke 2002; 33:2478-84; PMID:12364741; http://dx.doi.org/10.1161/01.STR.0000032302.91894.0F
    • (2002) Stroke , vol.33 , pp. 2478-2484
    • Hua, Y.1    Schallert, T.2    Keep, R.F.3    Wu, J.4    Hoff, J.T.5    Xi, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.