Chloroquine analogs as antimalarial candidates with potent in vitro and in vivo activity

International Journal for Parasitology: Drugs and Drug Resistance

Volumn 8, Issue 3, 2018, Pages 459-464

  Aguiar, Anna C C ^a   Murce, Erika ^b   Cortopassi, Wilian A ^c   Pimentel, Andre S ^b   Almeida, Maria M F S ^d   Barros, Daniele C S ^d   Guedes, Jéssica S ^d   Meneghetti, Mario R ^d   Krettli, Antoniana U ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FEDERAL UNIVERSITY OF ALAGOAS   (Brazil)

Author keywords

Chloroquine; Drug design; Malaria; Resistance

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; CHLOROQUINE DERIVATIVE; HEMATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; IC50; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MOLECULAR DOCKING; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG RESISTANCE; DRUG SENSITIVITY; HEP-G2 CELL LINE; HUMAN; ISOLATION AND PURIFICATION;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DRUG DESIGN; DRUG RESISTANCE; HEP G2 CELLS; HUMANS; MALARIA; MICE; PARASITIC SENSITIVITY TESTS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 85055863035     PISSN: None     EISSN: 22113207     Source Type: Journal    
DOI: 10.1016/j.ijpddr.2018.10.002     Document Type: Article

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