The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum

Molecular and Biochemical Parasitology

Volumn 88, Issue 1-2, 1997, Pages 215-224

  Menting, John G T ^a   Tilley, Leann ^b   Deady, Leslie W ^b   Ng, Ken ^c   Simpson, Richard J ^d   Cowman, Alan F ^a   Foley, Michael ^b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b LA TROBE UNIVERSITY   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Antimalarial drug; Chloroquine; Lactate dehydrogenase; Malaria; Photoaffinity labeling; Plasmodium falciparum

Indexed keywords

CHLOROQUINE; LACTATE DEHYDROGENASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVITY; IMMUNOPRECIPITATION; MALARIA; PHOTOAFFINITY LABELING; PHOTOREACTIVITY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; SEQUENTIAL ANALYSIS;

AFFINITY LABELS; AMINO ACID SEQUENCE; ANIMALS; ANTIMALARIALS; CARRIER PROTEINS; CHLOROQUINE; CLONING, MOLECULAR; ERYTHROCYTES; ESCHERICHIA COLI; HEMIN; HUMANS; L-LACTATE DEHYDROGENASE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTOZOAN PROTEINS; RABBITS; RECOMBINANT FUSION PROTEINS;

ORYCTOLAGUS CUNICULUS; PLASMODIUM FALCIPARUM;

EID: 0030795985     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00095-9     Document Type: Article

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