메뉴 건너뛰기




Volumn 1, Issue 20, 2016, Pages

miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85055609245     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.90301     Document Type: Article
Times cited : (41)

References (75)
  • 1
    • 84864740280 scopus 로고    scopus 로고
    • Pulmonary fibrosis: patterns and perpetrators
    • Noble PW, Barkauskas CE, Jiang D. Pulmonary fibrosis: patterns and perpetrators. J Clin Invest. 2012;122(8):2756–2762.
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2756-2762
    • Noble, PW1    Barkauskas, CE2    Jiang, D.3
  • 2
    • 0034802721 scopus 로고    scopus 로고
    • Rat alveolar type II cells inhibit lung fibroblast proliferation in vitro
    • Pan T, Mason RJ, Westcott JY, Shannon JM. Rat alveolar type II cells inhibit lung fibroblast proliferation in vitro. Am J Respir Cell Mol Biol. 2001;25(3):353–361.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , Issue.3 , pp. 353-361
    • Pan, T1    Mason, RJ2    Westcott, JY3    Shannon, JM.4
  • 3
    • 33644839990 scopus 로고    scopus 로고
    • Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha
    • Portnoy J, et al. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. Am J Physiol Lung Cell Mol Physiol. 2006;290(2):L307–L316.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , Issue.2 , pp. L307-L316
    • Portnoy, J1
  • 4
    • 0037309390 scopus 로고    scopus 로고
    • Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2
    • Moore BB, et al. Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2. Am J Physiol Lung Cell Mol Physiol. 2003;284(2):L342–L349.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , Issue.2 , pp. L342-L349
    • Moore, BB1
  • 5
    • 79960381007 scopus 로고    scopus 로고
    • Integrating mechanisms of pulmonary fibrosis
    • Wynn TA. Integrating mechanisms of pulmonary fibrosis. J Exp Med. 2011;208(7):1339–1350.
    • (2011) J Exp Med , vol.208 , Issue.7 , pp. 1339-1350
    • Wynn, TA.1
  • 6
    • 84925060829 scopus 로고    scopus 로고
    • Fibrosis-a common pathway to organ injury and failure
    • Rockey DC, Bell PD, Hill JA. Fibrosis-a common pathway to organ injury and failure. N Engl J Med. 2015;372(12):1138–1149.
    • (2015) N Engl J Med , vol.372 , Issue.12 , pp. 1138-1149
    • Rockey, DC1    Bell, PD2    Hill, JA.3
  • 7
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis
    • Munger JS, et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 1999;96(3):319–328.
    • (1999) Cell , vol.96 , Issue.3 , pp. 319-328
    • Munger, JS1
  • 8
    • 79958196781 scopus 로고    scopus 로고
    • TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment
    • Degryse AL, et al. TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment. Am J Physiol Lung Cell Mol Physiol. 2011;300(6):L887–L897.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300 , Issue.6 , pp. L887-L897
    • Degryse, AL1
  • 9
    • 78650925648 scopus 로고    scopus 로고
    • Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis
    • Li M, et al. Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis. J Clin Invest. 2011;121(1):277–287.
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 277-287
    • Li, M1
  • 10
    • 3543109115 scopus 로고    scopus 로고
    • Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis
    • Lee CG, et al. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med. 2004;200(3):377–389.
    • (2004) J Exp Med , vol.200 , Issue.3 , pp. 377-389
    • Lee, CG1
  • 11
    • 0030800795 scopus 로고    scopus 로고
    • Adenovector-mediated gene transfer of active transforming growth factorbeta1 induces prolonged severe fibrosis in rat lung
    • Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. Adenovector-mediated gene transfer of active transforming growth factorbeta1 induces prolonged severe fibrosis in rat lung. J Clin Invest. 1997;100(4):768–776.
    • (1997) J Clin Invest , vol.100 , Issue.4 , pp. 768-776
    • Sime, PJ1    Xing, Z2    Graham, FL3    Csaky, KG4    Gauldie, J.5
  • 12
    • 2142646426 scopus 로고    scopus 로고
    • TGF-beta signaling and the fibrotic response
    • Leask A, Abraham DJ. TGF-beta signaling and the fibrotic response. FASEB J. 2004;18(7):816–827.
    • (2004) FASEB J , vol.18 , Issue.7 , pp. 816-827
    • Leask, A1    Abraham, DJ.2
  • 13
    • 79960570500 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
    • Lawson WE, et al. Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs. Proc Natl Acad Sci U S A. 2011;108(26):10562–10567.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.26 , pp. 10562-10567
    • Lawson, WE1
  • 14
    • 65249088418 scopus 로고    scopus 로고
    • WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
    • Königshoff M, et al. WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest. 2009;119(4):772–787.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 772-787
    • Königshoff, M1
  • 15
    • 84903995680 scopus 로고    scopus 로고
    • Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation
    • Stuart BD, et al. Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Lancet Respir Med. 2014;2(7):557–565.
    • (2014) Lancet Respir Med , vol.2 , Issue.7 , pp. 557-565
    • Stuart, BD1
  • 16
    • 34250614359 scopus 로고    scopus 로고
    • Adult-onset pulmonary fibrosis caused by mutations in telomerase
    • Tsakiri KD, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci U S A. 2007;104(18):7552–7557.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.18 , pp. 7552-7557
    • Tsakiri, KD1
  • 17
    • 84908611170 scopus 로고    scopus 로고
    • Fibrosis: ultimate and proximate causes
    • Thannickal VJ, Zhou Y, Gaggar A, Duncan SR. Fibrosis: ultimate and proximate causes. J Clin Invest. 2014;124(11):4673–4677.
    • (2014) J Clin Invest , vol.124 , Issue.11 , pp. 4673-4677
    • Thannickal, VJ1    Zhou, Y2    Gaggar, A3    Duncan, SR.4
  • 18
    • 33744914050 scopus 로고    scopus 로고
    • Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
    • Thannickal VJ, Horowitz JC. Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc Am Thorac Soc. 2006;3(4):350–356.
    • (2006) Proc Am Thorac Soc , vol.3 , Issue.4 , pp. 350-356
    • Thannickal, VJ1    Horowitz, JC.2
  • 19
    • 84901810710 scopus 로고    scopus 로고
    • Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis
    • Richeldi L, et al. Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med. 2014;370(22):2071–2082.
    • (2014) N Engl J Med , vol.370 , Issue.22 , pp. 2071-2082
    • Richeldi, L1
  • 20
    • 37648998629 scopus 로고    scopus 로고
    • Getting to the root of miRNA-mediated gene silencing
    • Eulalio A, Huntzinger E, Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell. 2008;132(1):9–14.
    • (2008) Cell , vol.132 , Issue.1 , pp. 9-14
    • Eulalio, A1    Huntzinger, E2    Izaurralde, E.3
  • 21
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215–233.
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, DP.1
  • 23
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15–20.
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, BP1    Burge, CB2    Bartel, DP.3
  • 24
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99(24):15524–15529.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, GA1
  • 25
    • 74249084440 scopus 로고    scopus 로고
    • miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
    • Aqeilan RI, Calin GA, Croce CM. miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ. 2010;17(2):215–220.
    • (2010) Cell Death Differ , vol.17 , Issue.2 , pp. 215-220
    • Aqeilan, RI1    Calin, GA2    Croce, CM.3
  • 26
    • 84949773668 scopus 로고    scopus 로고
    • MicroRNAs as potential targets for progressive pulmonary fibrosis
    • Rajasekaran S, Rajaguru P, Sudhakar Gandhi PS. MicroRNAs as potential targets for progressive pulmonary fibrosis. Front Pharmacol. 2015;6:254.
    • (2015) Front Pharmacol , vol.6 , pp. 254
    • Rajasekaran, S1    Rajaguru, P2    Sudhakar Gandhi, PS.3
  • 28
    • 84857739552 scopus 로고    scopus 로고
    • MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
    • Madala SK, Schmidt S, Davidson C, Ikegami M, Wert S, Hardie WD. MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation. Am J Respir Cell Mol Biol. 2012;46(3):380–388.
    • (2012) Am J Respir Cell Mol Biol , vol.46 , Issue.3 , pp. 380-388
    • Madala, SK1    Schmidt, S2    Davidson, C3    Ikegami, M4    Wert, S5    Hardie, WD.6
  • 29
    • 84915748921 scopus 로고    scopus 로고
    • TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice
    • Rahaman SO, et al. TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. J Clin Invest. 2014;124(12):5225–5238.
    • (2014) J Clin Invest , vol.124 , Issue.12 , pp. 5225-5238
    • Rahaman, SO1
  • 30
    • 84880978616 scopus 로고    scopus 로고
    • Hedgehog signaling in neonatal and adult lung
    • Liu L, et al. Hedgehog signaling in neonatal and adult lung. Am J Respir Cell Mol Biol. 2013;48(6):703–710.
    • (2013) Am J Respir Cell Mol Biol , vol.48 , Issue.6 , pp. 703-710
    • Liu, L1
  • 31
    • 84884996785 scopus 로고    scopus 로고
    • Role of IGF-1 pathway in lung fibroblast activation
    • Hung CF, Rohani MG, Lee SS, Chen P, Schnapp LM. Role of IGF-1 pathway in lung fibroblast activation. Respir Res. 2013;14:102.
    • (2013) Respir Res , vol.14 , pp. 102
    • Hung, CF1    Rohani, MG2    Lee, SS3    Chen, P4    Schnapp, LM.5
  • 32
    • 48949119317 scopus 로고    scopus 로고
    • EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis
    • Hardie WD, et al. EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2008;294(6):L1217–L1225.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , Issue.6 , pp. L1217-L1225
    • Hardie, WD1
  • 33
    • 84979590841 scopus 로고    scopus 로고
    • MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2
    • [published online ahead of print June 10, 2016]
    • Kim RY et al. MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2 [published online ahead of print June 10, 2016]. J Allergy Clin Immunol. doi:10.1016/j.jaci.2016.04.038.
    • J Allergy Clin Immunol
    • Kim, RY1
  • 34
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
    • Rock JR, et al. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci U S A. 2011;108(52):E1475–E1483.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.52 , pp. E1475-E1483
    • Rock, JR1
  • 35
    • 60849098434 scopus 로고    scopus 로고
    • Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts
    • Kim Y, et al. Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. J Cell Biol. 2009;184(2):309–322.
    • (2009) J Cell Biol , vol.184 , Issue.2 , pp. 309-322
    • Kim, Y1
  • 36
    • 79954624848 scopus 로고    scopus 로고
    • AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes
    • Meissner M, et al. AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes. Exp Dermatol. 2011;20(5):425–429.
    • (2011) Exp Dermatol , vol.20 , Issue.5 , pp. 425-429
    • Meissner, M1
  • 37
    • 11144268038 scopus 로고    scopus 로고
    • Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells
    • Ringshausen I, et al. Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells. Leukemia. 2004;18(12):1964–1970.
    • (2004) Leukemia , vol.18 , Issue.12 , pp. 1964-1970
    • Ringshausen, I1
  • 38
    • 48949119341 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
    • Lawson WE, et al. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol. 2008;294(6):L1119–L1126.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , Issue.6 , pp. L1119-L1126
    • Lawson, WE1
  • 39
    • 84962821750 scopus 로고    scopus 로고
    • MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3
    • Wang C, et al. MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3. Oncotarget. 2016;7(12):14912–14924.
    • (2016) Oncotarget , vol.7 , Issue.12 , pp. 14912-14924
    • Wang, C1
  • 40
    • 1642269164 scopus 로고    scopus 로고
    • Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis
    • Hardie WD, Le Cras TD, Jiang K, Tichelaar JW, Azhar M, Korfhagen TR. Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2004;286(4):L741–L749.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286 , Issue.4 , pp. L741-L749
    • Hardie, WD1    Le Cras, TD2    Jiang, K3    Tichelaar, JW4    Azhar, M5    Korfhagen, TR.6
  • 41
    • 84900556191 scopus 로고    scopus 로고
    • Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis
    • Madala SK, et al. Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2014;306(8):L726–L735.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.306 , Issue.8 , pp. L726-L735
    • Madala, SK1
  • 42
    • 0035141395 scopus 로고    scopus 로고
    • Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP)
    • Barbas-Filho JV, Ferreira MA, Sesso A, Kairalla RA, Carvalho CR, Capelozzi VL. Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol. 2001;54(2):132–138.
    • (2001) J Clin Pathol , vol.54 , Issue.2 , pp. 132-138
    • Barbas-Filho, JV1    Ferreira, MA2    Sesso, A3    Kairalla, RA4    Carvalho, CR5    Capelozzi, VL.6
  • 43
    • 0032437815 scopus 로고    scopus 로고
    • Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung
    • (Pt 1)
    • Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol. 1998;275(6 Pt 1):L1192–L1199.
    • (1998) Am J Physiol , vol.275 , Issue.6 , pp. L1192-L1199
    • Uhal, BD1    Joshi, I2    Hughes, WF3    Ramos, C4    Pardo, A5    Selman, M.6
  • 44
    • 84877038719 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress as a pro-fibrotic stimulus
    • Tanjore H, Lawson WE, Blackwell TS. Endoplasmic reticulum stress as a pro-fibrotic stimulus. Biochim Biophys Acta. 2013;1832(7):940–947.
    • (2013) Biochim Biophys Acta , vol.1832 , Issue.7 , pp. 940-947
    • Tanjore, H1    Lawson, WE2    Blackwell, TS.3
  • 45
    • 54049115076 scopus 로고    scopus 로고
    • Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
    • Korfei M, et al. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2008;178(8):838–846.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.8 , pp. 838-846
    • Korfei, M1
  • 46
    • 84894283326 scopus 로고    scopus 로고
    • Genome-wide analysis of miRNA-mRNA interactions in marrow stromal cells
    • Balakrishnan I, et al. Genome-wide analysis of miRNA-mRNA interactions in marrow stromal cells. Stem Cells. 2014;32(3):662–673.
    • (2014) Stem Cells , vol.32 , Issue.3 , pp. 662-673
    • Balakrishnan, I1
  • 47
    • 84941087952 scopus 로고    scopus 로고
    • DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions
    • Vlachos IS, et al. DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions. Nucleic Acids Res. 2015;43(Database issue):D153–D159.
    • (2015) Nucleic Acids Res , vol.43 , Issue.Database issue , pp. D153-D159
    • Vlachos, IS1
  • 48
    • 33644849221 scopus 로고    scopus 로고
    • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase
    • Collins CS, et al. A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. Proc Natl Acad Sci U S A. 2006;103(10):3775–3780.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.10 , pp. 3775-3780
    • Collins, CS1
  • 50
    • 80055114454 scopus 로고    scopus 로고
    • Stanniocalcin-1 regulates re-epithelialization in human keratinocytes
    • Yeung BH, Wong CK. Stanniocalcin-1 regulates re-epithelialization in human keratinocytes. PLoS One. 2011;6(11):e27094.
    • (2011) PLoS One , vol.6 , Issue.11 , pp. e27094
    • Yeung, BH1    Wong, CK.2
  • 51
    • 84902581695 scopus 로고    scopus 로고
    • Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via targeting LAMC1 in prostate cancer
    • Nishikawa R, et al. Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via targeting LAMC1 in prostate cancer. Int J Oncol. 2014;45(1):401–410.
    • (2014) Int J Oncol , vol.45 , Issue.1 , pp. 401-410
    • Nishikawa, R1
  • 52
    • 84877086317 scopus 로고    scopus 로고
    • Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
    • Sakai N, Tager AM. Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis. Biochim Biophys Acta. 2013;1832(7):911–921.
    • (2013) Biochim Biophys Acta , vol.1832 , Issue.7 , pp. 911-921
    • Sakai, N1    Tager, AM.2
  • 53
    • 84886681643 scopus 로고    scopus 로고
    • Comparative evaluation of miRNA expression between in vitro and in vivo airway epithelium demonstrates widespread differences
    • Chen P, Edelman JD, Gharib SA. Comparative evaluation of miRNA expression between in vitro and in vivo airway epithelium demonstrates widespread differences. Am J Pathol. 2013;183(5):1405–1410.
    • (2013) Am J Pathol , vol.183 , Issue.5 , pp. 1405-1410
    • Chen, P1    Edelman, JD2    Gharib, SA.3
  • 55
    • 84961178977 scopus 로고    scopus 로고
    • miR-130b-3p modulates epithelial-mesenchymal crosstalk in lung fibrosis by targeting IGF-1
    • Li S, et al. miR-130b-3p modulates epithelial-mesenchymal crosstalk in lung fibrosis by targeting IGF-1. PLoS One. 2016;11(3):e0150418.
    • (2016) PLoS One , vol.11 , Issue.3 , pp. e0150418
    • Li, S1
  • 56
    • 84870508377 scopus 로고    scopus 로고
    • Profibrotic role of miR-154 in pulmonary fibrosis
    • Milosevic J, et al. Profibrotic role of miR-154 in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2012;47(6):879–887.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , Issue.6 , pp. 879-887
    • Milosevic, J1
  • 57
    • 84907958758 scopus 로고    scopus 로고
    • Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis
    • Liang H, et al. Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis. Cell Death Dis. 2014;5:e1238.
    • (2014) Cell Death Dis , vol.5 , pp. e1238
    • Liang, H1
  • 58
    • 84938991449 scopus 로고    scopus 로고
    • MicroRNA-144 dysregulates the transforming growth factor-β signaling cascade and contributes to the development of bronchiolitis obliterans syndrome after human lung transplantation
    • Xu Z, et al. MicroRNA-144 dysregulates the transforming growth factor-β signaling cascade and contributes to the development of bronchiolitis obliterans syndrome after human lung transplantation. J Heart Lung Transplant. 2015;34(9):1154–1162.
    • (2015) J Heart Lung Transplant , vol.34 , Issue.9 , pp. 1154-1162
    • Xu, Z1
  • 59
    • 84941762330 scopus 로고    scopus 로고
    • The anti-fibrotic effects and mechanisms of microRNA-486-5p in pulmonary fibrosis
    • Ji X, et al. The anti-fibrotic effects and mechanisms of microRNA-486-5p in pulmonary fibrosis. Sci Rep. 2015;5:14131.
    • (2015) Sci Rep , vol.5 , pp. 14131
    • Ji, X1
  • 60
    • 85008669389 scopus 로고    scopus 로고
    • miR-155 in the progression of lung fibrosis in systemic sclerosis
    • Christmann RB, et al. miR-155 in the progression of lung fibrosis in systemic sclerosis. Arthritis Res Ther. 2016;18(1):155.
    • (2016) Arthritis Res Ther , vol.18 , Issue.1 , pp. 155
    • Christmann, RB1
  • 61
    • 77955373730 scopus 로고    scopus 로고
    • miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
    • Liu G, et al. miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med. 2010;207(8):1589–1597.
    • (2010) J Exp Med , vol.207 , Issue.8 , pp. 1589-1597
    • Liu, G1
  • 62
    • 77955399498 scopus 로고    scopus 로고
    • Inhibition and role of let-7d in idiopathic pulmonary fibrosis
    • Pandit KV, et al. Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2010;182(2):220–229.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.2 , pp. 220-229
    • Pandit, KV1
  • 63
    • 84899741687 scopus 로고    scopus 로고
    • MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis
    • Das S, et al. MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2014;50(5):882–892.
    • (2014) Am J Respir Cell Mol Biol , vol.50 , Issue.5 , pp. 882-892
    • Das, S1
  • 64
    • 84873978112 scopus 로고    scopus 로고
    • Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis
    • Dakhlallah D, et al. Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med. 2013;187(4):397–405.
    • (2013) Am J Respir Crit Care Med , vol.187 , Issue.4 , pp. 397-405
    • Dakhlallah, D1
  • 65
    • 84906078197 scopus 로고    scopus 로고
    • miR-210 promotes IPF fibroblast proliferation in response to hypoxia
    • Bodempudi V, et al. miR-210 promotes IPF fibroblast proliferation in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2014;307(4):L283–L294.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , Issue.4 , pp. L283-L294
    • Bodempudi, V1
  • 66
    • 84977270999 scopus 로고    scopus 로고
    • miR-34 miRNAs regulate cellular senescence in type II alveolar epithelial cells of patients with idiopathic pulmonary fibrosis
    • Disayabutr S, et al. miR-34 miRNAs regulate cellular senescence in type II alveolar epithelial cells of patients with idiopathic pulmonary fibrosis. PLoS One. 2016;11(6):e0158367.
    • (2016) PLoS One , vol.11 , Issue.6 , pp. e0158367
    • Disayabutr, S1
  • 67
    • 84943279279 scopus 로고    scopus 로고
    • miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
    • Su S, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523.
    • (2015) Nat Commun , vol.6 , pp. 8523
    • Su, S1
  • 68
    • 84908087700 scopus 로고    scopus 로고
    • MicroRNA mimicry blocks pulmonary fibrosis
    • Montgomery RL, et al. MicroRNA mimicry blocks pulmonary fibrosis. EMBO Mol Med. 2014;6(10):1347–1356.
    • (2014) EMBO Mol Med , vol.6 , Issue.10 , pp. 1347-1356
    • Montgomery, RL1
  • 69
    • 84958610488 scopus 로고    scopus 로고
    • HDAC3-dependent epigenetic pathway controls lung alveolar epithelial cell remodeling and spreading via miR-17-92 and TGF-β signaling regulation
    • Wang Y, et al. HDAC3-dependent epigenetic pathway controls lung alveolar epithelial cell remodeling and spreading via miR-17-92 and TGF-β signaling regulation. Dev Cell. 2016;36(3):303–315.
    • (2016) Dev Cell , vol.36 , Issue.3 , pp. 303-315
    • Wang, Y1
  • 70
    • 85032719462 scopus 로고    scopus 로고
    • Acute cellular rejection elicits distinct microRNA signatures in airway epithelium of lung transplant patients
    • Gharib SA, Edelman JD, Ge L, Chen P. Acute cellular rejection elicits distinct microRNA signatures in airway epithelium of lung transplant patients. Transplant Direct. 2015;1(10).
    • (2015) Transplant Direct , vol.1 , Issue.10
    • Gharib, SA1    Edelman, JD2    Ge, L3    Chen, P.4
  • 71
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 2001;98(9):5116–5121.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.9 , pp. 5116-5121
    • Tusher, VG1    Tibshirani, R2    Chu, G.3
  • 72
    • 84880617636 scopus 로고    scopus 로고
    • WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
    • Wang J, Duncan D, Shi Z, Zhang B. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res. 2013;41(Web Server issue):W77–W83.
    • (2013) Nucleic Acids Res , vol.41 , Issue.Web Server issue , pp. W77-W83
    • Wang, J1    Duncan, D2    Shi, Z3    Zhang, B.4
  • 73
    • 79952788040 scopus 로고    scopus 로고
    • β-Arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix
    • Lovgren AK, et al. β-Arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. Sci Transl Med. 2011;3(74):74ra23.
    • (2011) Sci Transl Med , vol.3 , Issue.74 , pp. 74ra23
    • Lovgren, AK1
  • 74
    • 34247862243 scopus 로고    scopus 로고
    • Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice
    • Pierce EM, et al. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice. Am J Pathol. 2007;170(4):1152–1164.
    • (2007) Am J Pathol , vol.170 , Issue.4 , pp. 1152-1164
    • Pierce, EM1
  • 75
    • 84988980824 scopus 로고    scopus 로고
    • Syndecan-1 attenuates lung injury during influenza infection by potentiating c-met signaling to suppress epithelial apoptosis
    • Brauer R, et al. Syndecan-1 attenuates lung injury during influenza infection by potentiating c-met signaling to suppress epithelial apoptosis. Am J Respir Crit Care Med. 2016;194(3):333–344.
    • (2016) Am J Respir Crit Care Med , vol.194 , Issue.3 , pp. 333-344
    • Brauer, R1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.