Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 8, 2014, Pages

  Madala, Satish K ^a   Korfhagen, Thomas R ^a   Schmidt, Stephanie ^a   Davidson, Cynthia ^a   Edukulla, Ramakrishna ^a   Ikegami, Machiko ^a   Violette, Shelia M ^b   Weinreb, Paul H ^b   Sheppard, Dean ^c   Hardie, William D ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b BIOGEN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Epidermal growth factor receptor; Integrin; Pleural fibrosis; Pulmonary fibrosis; TGF

Indexed keywords

ALPHAVBETA6 INTEGRIN; BETA6 INTEGRIN; DOXYCYCLINE; RECEPTOR ANTIBODY; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HISTOPATHOLOGY; LUNG FIBROSIS; LUNG MECHANICS; MOUSE; NONHUMAN; PHYSIOLOGICAL PROCESS; PLEURA THICKENING; PRIORITY JOURNAL;

EPIDERMAL GROWTH FACTOR RECEPTOR; INTEGRIN; PLEURAL FIBROSIS; PULMONARY FIBROSIS; TGF-Β;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, NEUTRALIZING; ANTIGENS, NEOPLASM; BRONCHOALVEOLAR LAVAGE; COLLAGEN; DOXYCYCLINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INTEGRINS; MALE; MICE; MICE, TRANSGENIC; PULMONARY FIBROSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; UTEROGLOBIN;

EID: 84900556191     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00357.2013     Document Type: Article

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