Stanniocalcin-1 regulates Re-Epithelialization in human Keratinocytes

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Yeung, Bonnie H Y ^a   Wong, Chris K C ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; FOCAL ADHESION KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; HYPOCALCIN; IONOMYCIN; LITHIUM CHLORIDE; PROTEIN KINASE B; STANNIOCALCIN 1; STAUROSPORINE; UNCLASSIFIED DRUG; CALCIUM; ENZYME INHIBITOR; FIBRONECTIN; FOCAL ADHESION KINASE 1; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; GLYCOPROTEIN; SMALL INTERFERING RNA;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIZATION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; LAMELLIPODIUM; PROTEIN EXPRESSION; RE EPITHELIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STC1 GENE; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PSEUDOPODIUM; WOUND HEALING;

CALCIUM; CELL MOVEMENT; CELLS, CULTURED; ENZYME INHIBITORS; EPITHELIAL CELLS; FIBRONECTINS; FOCAL ADHESION KINASE 1; GLYCOGEN SYNTHASE KINASE 3; GLYCOPROTEINS; HUMANS; KERATINOCYTES; PHOSPHORYLATION; PSEUDOPODIA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAUROSPORINE; WOUND HEALING;

EID: 80055114454     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027094     Document Type: Article

References (53)

1. Varghese R, Wong CK, Deol H, Wagner GF, DiMattia GE, (1998) Comparative analysis of mammalian stanniocalcin genes. Endocrinology 139: 4714-4725.
2. De Niu P, Radman DP, Jaworski EM, Deol H, Gentz R, et al. (2000) Development of a human stanniocalcin radioimmunoassay: serum and tissue hormone levels and pharmacokinetics in the rat. Molecular and Cellular Endocrinology 162: 131-144.
3. Lai KP, Law AYS, Yeung HY, Lee LS, Wagner GF, et al. (2007) Induction of stanniocalcin-1 expression in apoptotic human nasopharyngeal cancer cells by p53. Biochemical and Biophysical Research Communications 356: 968-975.
4. Law AYS, Lai KP, Lui WC, Wan HT, Wong CKC, (2008) Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. Experimental Cell Research 314: 2975-2984.
5. Wu S, Yoshiko Y, De Luca F, (2006) Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. The Journal of biological chemistry 281: 5120-5127.
6. Chakraborty A, Brooks H, Zhang P, Smith W, McReynolds MR, et al. (2007) Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes. American Journal of Physiology-Renal Physiology 292: F895-F904.
7. Sheikh-Hamad D, (2010) Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. American Journal of Physiology-Renal Physiology 298: F248-F254.
8. Klein D, Demory A, Peyre F, Kroll J, Geraud C, et al. (2009) Wnt2 acts as an angiogenic growth factor for non-sinusoidal endothelial cells and inhibits expression of stanniocalcin-1. Angiogenesis 12: 251-265.
9. Zlot C, Ingle G, Hongo J, Yang S, Sheng Z, et al. (2003) Stanniocalcin 1 is an autocrine modulator of endothelial angiogenic responses to hepatocyte growth factor. Journal of Biological Chemistry 278: 47654-47659.
10. Paciga M, McCudden CR, Londos C, DiMattia GE, Wagner GF, (2003) Targeting of big stanniocalcin and its receptor to lipid storage droplets of ovarian steroidogenic cells. The Journal of biological chemistry 278: 49549-49554.
11. Chandran UR, Ma CQ, Dhir R, Bisceglia M, Lyons-Weiler M, et al. (2007) Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process. Bmc Cancer 7.
12. Chang AC, Jellinek DA, Reddel RR, (2003) Mammalian stanniocalcins and cancer. Endocr Relat Cancer 10: 359-373.
13. Joensuu K, Heikkila P, Andersson LC, (2008) Tumor dormancy: Elevated expression of stanniocalcins in late relapsing breast cancer. Cancer Letters 265: 76-83.
14. Liu G, Yang G, Chang B, Mercado-Uribe I, Huang M, et al. (2010) Stanniocalcin 1 and ovarian tumorigenesis. J Natl Cancer Inst 102: 812-827.
15. McCudden CR, Majewski A, Chakrabarti S, Wagner GF, (2004) Co-localization of stanniocalcin-1 ligand and receptor in human breast carcinomas. Molecular and Cellular Endocrinology 213: 167-172.
16. Salabat MR, Ding XZ, Ujiki MB, Wagner GF, DiMattia GE, et al. (2005) Upregulation of stanniocalcin-1 in pancreatic cancer. Gastroenterology 128: A532-A533.
17. Tamura S, Oshima T, Yoshihara K, Kanazawa A, Yamada T, et al. (2011) Clinical Significance of STC1 Gene Expression in Patients with Colorectal Cancer. Anticancer Res 31: 325-329.
18. Tohmiya Y, Koide Y, Fujimaki S, Harigae H, Funato T, et al. (2004) Stanniocalcin-1 as a novel marker to detect minimal residual disease of human leukemia. Tohoku Journal of Experimental Medicine 204: 125-133.
19. Wascher RA, Huynh KT, Giuliano AW, Hansen NM, Singer FR, et al. (2003) Stanniocalcin-1: A novel molecular blood and bone marrow marker for human breast cancer. Clinical Cancer Research 9: 1427-1435.
20. Schafer M, Werner S, (2008) Cancer as an overhealing wound: an old hypothesis revisited. Nature reviews Molecular cell biology 9: 628-638.
21. Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, et al. (2004) Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS biology 2: E7.
22. Rodero MP, Khosrotehrani K, (2010) Skin wound healing modulation by macrophages. Int J Clin Exp Pathol 3: 643-653.
23. Barbul A, Regan MC, (1995) Immune involvement in wound healing. Otolaryngologic clinics of North America 28: 955-968.
24. Rasouly D, Lazarovici P, (1994) Staurosporine induces tyrosine phosphorylation of a 145 kDa protein but does not activate gp140trk in PC12 cells. European journal of pharmacology 269: 255-264.
25. Sako T, Tauber AI, Jeng AY, Yuspa SH, Blumberg PM, (1988) Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells. Cancer research 48: 4646-4650.
26. Yoshimura M, Nishikawa A, Nishiura T, Ihara Y, Kanayama Y, et al. (1995) Cell spreading in Colo 201 by staurosporin is alpha 3 beta 1 integrin-mediated with tyrosine phosphorylation of Src and tensin. The Journal of biological chemistry 270: 2298-2304.
27. Koivisto L, Alavian K, Hakkinen L, Pelech S, McCulloch CA, et al. (2003) Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes. Journal of Cell Science 116: 3749-3760.
28. Hunt TK, Hopf H, Hussain Z, (2000) Physiology of wound healing. Adv Skin Wound Care 13: 6-11.
29. Schlaepfer DD, Hauck CR, Sieg DJ, (1999) Signaling through focal adhesion kinase. Progress in biophysics and molecular biology 71: 435-478.
30. Buttrick GJ, Wakefield JG, (2008) PI3-K and GSK-3: Akt-ing together with microtubules. Cell cycle 7: 2621-2625.
31. Basini G, Bussolati S, Santini SE, Grasselli F, (2009) Stanniocalcin, a potential ovarian angiogenesis regulator, does not affect endothelial cell apoptosis. Ann N Y Acad Sci 1171: 94-99.
32. Holmes DIR, Zachary IC, (2008) Vascular endothelial growth factor regulates Stanniocalcin-1 expression via Neuropilin-1-dependent regulation of KDR and synergism with fibroblast growth Factor-2. Cellular Signalling 20: 569-579.
33. Lal A, Peters H, St Croix B, Haroon ZA, Dewhirst MW, et al. (2001) Transcriptional response to hypoxia in human tumors. Journal of the National Cancer Institute 93: 1337-1343.
34. Law AYS, Ching LY, Lai KP, Wong CKC, (2010) Identification and characterization of the hypoxia-responsive element in human stanniocalcin-1 gene. Molecular and Cellular Endocrinology 314: 118-127.
35. Nguyen A, Chang ACM, Reddel RR, (2009) Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1/2 signaling pathway during oxidative stress. Oncogene 28: 1982-1992.
36. Wary KK, Thakker GD, Humtsoe JO, Yang J, (2003) Analysis of VEGF-responsive genes involved in the activation of endothelial cells. Molecular Cancer 2: 25.
37. Westberg JA, Serlachius M, Lankila P, Penkowa M, Hidalgo J, et al. (2007) Hypoxic preconditioning induces neuroprotective stanniocalcin-1 in brain via IL-6 signaling. Stroke 38: 1025-1030.
38. Yeung HY, Lai KP, Chan HY, Mak NK, Wagner GF, et al. (2005) Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells. Endocrinology 146: 4951-4960.
39. Jauhiainen S, Hakkinen SK, Toivanen PI, Heinonen SE, Jyrkkanen HK, et al. (2011) Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects. Arteriosclerosis, thrombosis, and vascular biology 31: 1617-1624.
40. Lauffenburger DA, Horwitz AF, (1996) Cell migration: a physically integrated molecular process. Cell 84: 359-369.
41. Kruman I, Guo Q, Mattson MP, (1998) Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J Neurosci Res 51: 293-308.
42. Lansdown AB, (2002) Calcium: a potential central regulator in wound healing in the skin. Wound repair and regeneration: official publication of the Wound Healing Society [and] the European Tissue Repair Society 10: 271-285.
43. Diaz-Velasquez CE, Castro-Munozledo F, Kuri-Harcuch W, (2008) Staurosporine rapidly commits 3T3-F442A cells to the formation of adipocytes by activation of GSK-3beta and mobilization of calcium. Journal of cellular biochemistry 105: 147-157.
44. Glading A, Lauffenburger DA, Wells A, (2002) Cutting to the chase: calpain proteases in cell motility. Trends in cell biology 12: 46-54.
45. Kanellis J, Bick R, Garcia G, Truong L, Tsao CC, et al. (2004) Stanniocalcin-1, an inhibitor of macrophage chemotaxis and chemokinesis. American Journal of Physiology-Renal Physiology 286: F356-F362.
46. Sheikh-Hamad D, Bick R, Wu GY, Christensen BM, Razeghi P, et al. (2003) Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure. American Journal of Physiology-Heart and Circulatory Physiology 285: H442-H448.
47. Wendelaar Bonga SE, Pang PK, (1991) Control of calcium regulating hormones in the vertebrates: parathyroid hormone, calcitonin, prolactin, and stanniocalcin. International review of cytology 128: 139-213.
48. Manning BD, Cantley LC, (2007) AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274.
49. Vaidya RJ, Ray RM, Johnson LR, (2006) Akt-mediated GSK-3beta inhibition prevents migration of polyamine-depleted intestinal epithelial cells via Rac1. Cellular and molecular life sciences: CMLS 63: 2871-2879.
50. Kane LP, Shapiro VS, Stokoe D, Weiss A, (1999) Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol 9: 601-604.
51. Yeung HY, Chan DK, Mak NK, Wagner GF, Wong CK, (2003) Identification of signal transduction pathways that modulate dibutyryl cyclic adenosine monophosphate activation of stanniocalcin gene expression in neuroblastoma cells. Endocrinology 144: 4446-4452.
52. Mayo LD, Donner DB, (2001) A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proceedings of the National Academy of Sciences of the United States of America 98: 11598-11603.
53. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, et al. (1988) Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. The Journal of cell biology 106: 761-771.