Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

Frontiers in Immunology

Volumn 9, Issue , 2018, Pages

  Krischuns, Tim ^a   Günl, Franziska ^a   Henschel, Lea ^a   Binder, Marco ^b   Willemsen, Joschka ^b   Schloer, Sebastian ^a   Rescher, Ursula ^a   Gerlt, Vanessa ^a   Zimmer, Gert ^c,d   Nordhoff, Carolin ^a   Ludwig, Stephan ^a   Brunotte, Linda ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (Switzerland)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

IFN ; influenza; innate immunity; KAP1; PKR; RIG I; TIF1 beta; TRIM28

Indexed keywords

BETA INTERFERON; DDX58 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN AND STRESS-ACTIVATED PROTEIN KINASE 1; RETINOIC ACID INDUCIBLE PROTEIN I; S6 KINASE; TRANSCRIPTION INTERMEDIARY FACTOR 1 BETA; TRIM28 PROTEIN, HUMAN;

A-549 CELL LINE; ANALYSIS OF VARIANCE; ANIMAL; CHLOROCEBUS AETHIOPS; CRISPR CAS SYSTEM; EPITHELIUM CELL; GENE KNOCKDOWN; GENE TRANSFER; GENETICS; HEK293 CELL LINE; HUMAN; INFLUENZA; INFLUENZA A VIRUS; LUNG; METABOLISM; PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL; VIROLOGY;

A549 CELLS; ANALYSIS OF VARIANCE; ANIMALS; CERCOPITHECUS AETHIOPS; CRISPR-CAS SYSTEMS; DEAD BOX PROTEIN 58; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; INTERFERON-BETA; LUNG; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; TRIPARTITE MOTIF-CONTAINING PROTEIN 28;

EID: 85054893218     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2018.02229     Document Type: Article

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