TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming

Stem Cells

Volumn 35, Issue 1, 2017, Pages 147-157

  Miles, Denise Catherine ^a,c   de Vries, Nienke Alexandra ^a   Gisler, Santiago ^a   Lieftink, Cor ^a   Akhtar, Waseem ^a   Gogola, Ewa ^a   Pawlitzky, Inka ^a   Hulsman, Danielle ^a   Tanger, Ellen ^a   Koppens, Martijn ^a   Beijersbergen, Roderick Leonardus ^a   van Lohuizen, Maarten ^a,b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b Cancer Genomics Center (CGCnl)   (Netherlands)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Epigenetics; Induced pluripotent stem cells; Reprogramming; Trim28

Indexed keywords

PEPTIDES AND PROTEINS; SHORT HAIRPIN RNA; TRIPARTITE MOTIF CONTAINING 28 PROTEIN; UNCLASSIFIED DRUG; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; SETDB1 PROTEIN, MOUSE; SMALL INTERFERING RNA; TRANSCRIPTION INTERMEDIARY FACTOR 1 BETA; TRIM28 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; ENDOGENOUS RETROVIRUS; EPIGENETICS; FIBROBLAST; GENE REPRESSION; GENE SILENCING; IMMORTALIZED CELL LINE; INDUCED PLURIPOTENT STEM CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PROTEIN FUNCTION; SOMATIC CELL; ANIMAL; BIOLOGICAL MODEL; CELL PROLIFERATION; CHROMATIN; CYTOLOGY; GENETIC EPIGENESIS; GENETICS; METABOLISM; METHYLATION; PLURIPOTENT STEM CELL; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CELLULAR REPROGRAMMING; CHROMATIN; ENDOGENOUS RETROVIRUSES; EPIGENESIS, GENETIC; GENE KNOCKDOWN TECHNIQUES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LYSINE; METHYLATION; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PLURIPOTENT STEM CELLS; RNA, SMALL INTERFERING; TRIPARTITE MOTIF-CONTAINING PROTEIN 28; UP-REGULATION;

EID: 84978946303     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2453     Document Type: Article

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