Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 37, 2018, Pages E8688-E8697

  Ene, Iuliana V ^a   Farrer, Rhys A ^b   Hirakawa, Matthew P ^a   Agwamba, Kennedy ^b   Cuomo, Christina A ^b   Bennett, Richard J ^a  

^a BROWN UNIVERSITY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

Aneuploidy; Candida albicans; Diploid species; LOH; Microevolution

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CHROMOSOME 7; CONTROLLED STUDY; DIPLOIDY; EVOLUTION; FEMALE; FUNGAL GENOME; FUNGAL VIRULENCE; FUNGUS ISOLATION; GENETIC ASSOCIATION; HETEROZYGOSITY LOSS; IN VITRO STUDY; IN VIVO STUDY; MICROEVOLUTION; MOUSE; MUTAGENESIS; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; REPRODUCTIVE FITNESS; SINGLE NUCLEOTIDE POLYMORPHISM; SUPERNUMERARY CHROMOSOME; TRISOMY; WHOLE GENOME SEQUENCING; CHROMOSOME; GENETIC SELECTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HETEROZYGOTE; HUMAN; MICROBIOLOGY; MOLECULAR EVOLUTION; MUTATION;

CANDIDA ALBICANS; CANDIDIASIS; CHROMOSOMES, FUNGAL; DIPLOIDY; EVOLUTION, MOLECULAR; GENOME, FUNGAL; HETEROZYGOTE; HUMANS; LOSS OF HETEROZYGOSITY; MUTATION; SELECTION, GENETIC;

EID: 85053053599     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1806002115     Document Type: Article

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