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Volumn 44, Issue 5, 2018, Pages 407-417

Daidzein, its effects on impaired glucose and lipid metabolism and vascular inflammation associated with type 2 diabetes

Author keywords

adjuvant therapeutic; daidzein; impaired glucose and lipid metabolism; type 2 diabetes; vascular inflammation

Indexed keywords

DAIDZEIN; GLUCOSE; LIPID; ANTIDIABETIC AGENT; ISOFLAVONE DERIVATIVE;

EID: 85052910881     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1439     Document Type: Review
Times cited : (91)

References (75)
  • 1
    • 33749160353 scopus 로고    scopus 로고
    • Estimated Asian adult soy protein and isoflavone intakes
    • Messina, M., Nagata, C., and Wu, A. H. (2006) Estimated Asian adult soy protein and isoflavone intakes. Nutr. Cancer. 55, 1–12
    • (2006) Nutr. Cancer. , vol.55 , pp. 1-12
    • Messina, M.1    Nagata, C.2    Wu, A.H.3
  • 2
    • 84881551200 scopus 로고    scopus 로고
    • Dietary flavonoid and lignan intake and mortality in a Spanish cohort
    • Zamora-Ros, R., Jimenez, C., Cleries, R., Agudo, A., Sanchez, M. J., et al. (2013) Dietary flavonoid and lignan intake and mortality in a Spanish cohort. Epidemiology. 24, 726–733
    • (2013) Epidemiology. , vol.24 , pp. 726-733
    • Zamora-Ros, R.1    Jimenez, C.2    Cleries, R.3    Agudo, A.4    Sanchez, M.J.5
  • 3
    • 13444292085 scopus 로고    scopus 로고
    • Prospective study on usual dietary phytoestrogen intake and cardiovascular disease risk in Western women
    • van der Schouw, Y. T., Kreijkamp-Kaspers, S., Peeters, P. H., Keinan-Boker, L., Rimm, E. B., et al. (2005) Prospective study on usual dietary phytoestrogen intake and cardiovascular disease risk in Western women. Circulation. 111, 465–471
    • (2005) Circulation. , vol.111 , pp. 465-471
    • van der Schouw, Y.T.1    Kreijkamp-Kaspers, S.2    Peeters, P.H.3    Keinan-Boker, L.4    Rimm, E.B.5
  • 4
    • 33847789892 scopus 로고    scopus 로고
    • Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women
    • Mink, P. J., Scrafford, C. G., Barraj, L. M., Harnack, L., Hong, C. P., et al. (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am. J. Clin. Nutr. 85, 895–909
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 895-909
    • Mink, P.J.1    Scrafford, C.G.2    Barraj, L.M.3    Harnack, L.4    Hong, C.P.5
  • 7
    • 74549197901 scopus 로고    scopus 로고
    • Antidiabetic effects of fermented soybean products on type 2 diabetes
    • Kwon, D. Y., Daily, J. W., 3rd, Kim, H. J., and Park, S. (2010) Antidiabetic effects of fermented soybean products on type 2 diabetes. Nutr. Res. 30, 1–13
    • (2010) Nutr. Res. , vol.30 , pp. 1-13
    • Kwon, D.Y.1    Daily, J.W.2    Kim, H.J.3    Park, S.4
  • 8
    • 0034114568 scopus 로고    scopus 로고
    • Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora
    • Rowland, I. R., Wiseman, H., Sanders, T. A., Adlercreutz, H., and Bowey, E. A. (2000) Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora. Nutr. Cancer. 36, 27–32
    • (2000) Nutr. Cancer. , vol.36 , pp. 27-32
    • Rowland, I.R.1    Wiseman, H.2    Sanders, T.A.3    Adlercreutz, H.4    Bowey, E.A.5
  • 9
    • 77955845051 scopus 로고    scopus 로고
    • Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity
    • Cho, K. W., Lee, O. H., Banz, W. J., Moustaid-Moussa, N., Shay, N. F., et al. (2010) Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity. J. Nutr. Biochem. 21, 841–847
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 841-847
    • Cho, K.W.1    Lee, O.H.2    Banz, W.J.3    Moustaid-Moussa, N.4    Shay, N.F.5
  • 10
    • 84893391990 scopus 로고    scopus 로고
    • Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes and ob/ob mice
    • Cheong, S. H., Furuhashi, K., Ito, K., Nagaoka, M., Yonezawa, T., et al. (2014) Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes and ob/ob mice. Mol. Nutr. Food Res. 58, 267–277
    • (2014) Mol. Nutr. Food Res. , vol.58 , pp. 267-277
    • Cheong, S.H.1    Furuhashi, K.2    Ito, K.3    Nagaoka, M.4    Yonezawa, T.5
  • 11
    • 0033951110 scopus 로고    scopus 로고
    • Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes
    • Jung, W., Yu, O., Lau, S. M., O'Keefe, D. P., Odell, J., et al. (2000) Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes. Nat. Biotechnol. 18, 208–212
    • (2000) Nat. Biotechnol. , vol.18 , pp. 208-212
    • Jung, W.1    Yu, O.2    Lau, S.M.3    O'Keefe, D.P.4    Odell, J.5
  • 14
    • 33751157555 scopus 로고
    • Isoflavones and their conjugates in soy foods: extraction conditions and analysis by HPLC-mass spectrometry
    • Barnes, S., Kirk, M., and Coward, L. (1994) Isoflavones and their conjugates in soy foods: extraction conditions and analysis by HPLC-mass spectrometry. J. Agric. Food Chem. 42, 2466–2474
    • (1994) J. Agric. Food Chem. , vol.42 , pp. 2466-2474
    • Barnes, S.1    Kirk, M.2    Coward, L.3
  • 15
    • 0036721557 scopus 로고    scopus 로고
    • Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage
    • Shelnutt, S. R., Cimino, C. O., Wiggins, P. A., Ronis, M. J., and Badger, T. M. (2002) Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage. Am. J. Clin. Nutr. 76, 588–594
    • (2002) Am. J. Clin. Nutr. , vol.76 , pp. 588-594
    • Shelnutt, S.R.1    Cimino, C.O.2    Wiggins, P.A.3    Ronis, M.J.4    Badger, T.M.5
  • 16
    • 0036895683 scopus 로고    scopus 로고
    • Beneficial role of dietary phytoestrogens in obesity and diabetes
    • Bhathena, S. J., and Velasquez, M. T. (2002) Beneficial role of dietary phytoestrogens in obesity and diabetes. Am. J. Clin. Nutr. 76, 1191–1201
    • (2002) Am. J. Clin. Nutr. , vol.76 , pp. 1191-1201
    • Bhathena, S.J.1    Velasquez, M.T.2
  • 17
    • 0011820975 scopus 로고    scopus 로고
    • U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Nutrient Data Laboratory, Beltsville, MD
    • USDA. (2007) USDA-Iowa State University database on the isoflavone content of foods. U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Nutrient Data Laboratory, Beltsville, MD
    • (2007) USDA-Iowa State University database on the isoflavone content of foods
  • 18
    • 33847411931 scopus 로고    scopus 로고
    • Role of dietary soy protein in obesity
    • Velasquez, M. T., and Bhathena, S. J. (2007) Role of dietary soy protein in obesity. Int. J. Med. Sci. 4, 72–82
    • (2007) Int. J. Med. Sci. , vol.4 , pp. 72-82
    • Velasquez, M.T.1    Bhathena, S.J.2
  • 19
    • 33751158078 scopus 로고
    • Isoflavone content in commercial soybean foods
    • Wang, H., and Murphy, P. A. (1994) Isoflavone content in commercial soybean foods. J. Agric. Food Chem. 42, 1666–1673
    • (1994) J. Agric. Food Chem. , vol.42 , pp. 1666-1673
    • Wang, H.1    Murphy, P.A.2
  • 20
    • 0027134712 scopus 로고
    • Genistein, daidzein, and their.beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets
    • Coward, L., Barnes, N. C., Setchell, K. D. R., and Barnes, S. (1993) Genistein, daidzein, and their.beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets. J. Agric. Food Chem. 41, 1961–1967
    • (1993) J. Agric. Food Chem. , vol.41 , pp. 1961-1967
    • Coward, L.1    Barnes, N.C.2    Setchell, K.D.R.3    Barnes, S.4
  • 21
    • 77953061998 scopus 로고    scopus 로고
    • Isoflavone conversion of black soybean by immobilized Rhizopus spp
    • Cheng, K.-C., Lin, J.-T., Wu, J.-Y., and Liu, W.-H. (2010) Isoflavone conversion of black soybean by immobilized Rhizopus spp. Food Biotechnol. 24, 312–331
    • (2010) Food Biotechnol. , vol.24 , pp. 312-331
    • Cheng, K.-C.1    Lin, J.-T.2    Wu, J.-Y.3    Liu, W.-H.4
  • 22
    • 67349255696 scopus 로고    scopus 로고
    • Improvement of isoflavone aglycones production using β-glucosidase secretory produced in recombinant Aspergillus oryzae
    • Horii, K., Adachi, T., Matsuda, T., Tanaka, T., Sahara, H., et al. (2009) Improvement of isoflavone aglycones production using β-glucosidase secretory produced in recombinant Aspergillus oryzae. J. Mol. Catal. B Enzym. 59, 297–301
    • (2009) J. Mol. Catal. B Enzym. , vol.59 , pp. 297-301
    • Horii, K.1    Adachi, T.2    Matsuda, T.3    Tanaka, T.4    Sahara, H.5
  • 23
    • 37249075104 scopus 로고    scopus 로고
    • Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto
    • Kuo, L. C., Cheng, W. Y., Wu, R. Y., Huang, C. J., and Lee, K. T. (2006) Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto. Appl. Microb. Biotechnol. 73, 314–320
    • (2006) Appl. Microb. Biotechnol. , vol.73 , pp. 314-320
    • Kuo, L.C.1    Cheng, W.Y.2    Wu, R.Y.3    Huang, C.J.4    Lee, K.T.5
  • 24
    • 33750687894 scopus 로고    scopus 로고
    • Analysis of isoflavones in foods and dietary supplements
    • Delmonte, P., and Rader, J. I. (2006) Analysis of isoflavones in foods and dietary supplements. J AOAC Int. 89, 1138–1146
    • (2006) J AOAC Int. , vol.89 , pp. 1138-1146
    • Delmonte, P.1    Rader, J.I.2
  • 25
    • 84862845344 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots
    • Jin, S. E., Son, Y. K., Min, B. S., Jung, H. A., and Choi, J. S. (2012) Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots. Arch. Pharm. Res. 35, 823–837
    • (2012) Arch. Pharm. Res. , vol.35 , pp. 823-837
    • Jin, S.E.1    Son, Y.K.2    Min, B.S.3    Jung, H.A.4    Choi, J.S.5
  • 26
    • 0037817324 scopus 로고    scopus 로고
    • Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry
    • Prasain, J. K., Jones, K., Kirk, M., Wilson, L., Smith-Johnson, M., et al. (2003) Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 51, 4213–4218
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 4213-4218
    • Prasain, J.K.1    Jones, K.2    Kirk, M.3    Wilson, L.4    Smith-Johnson, M.5
  • 27
    • 84908572968 scopus 로고    scopus 로고
    • Pueraria tuberosa: a review on its phytochemical and therapeutic potential
    • Maji, A. K., Pandit, S., Banerji, P., and Banerjee, D. (2014) Pueraria tuberosa: a review on its phytochemical and therapeutic potential. Nat. Prod. Res. 28, 2111–2127
    • (2014) Nat. Prod. Res. , vol.28 , pp. 2111-2127
    • Maji, A.K.1    Pandit, S.2    Banerji, P.3    Banerjee, D.4
  • 28
    • 0031741608 scopus 로고    scopus 로고
    • Chemical modification of isoflavones in soyfoods during cooking and processing
    • Coward, L., Smith, M., Kirk, M., and Barnes, S. (1998) Chemical modification of isoflavones in soyfoods during cooking and processing. Am. J. Clin. Nutr. 68, 1486S–1491S
    • (1998) Am. J. Clin. Nutr. , vol.68 , pp. 1486S-1491S
    • Coward, L.1    Smith, M.2    Kirk, M.3    Barnes, S.4
  • 29
    • 34848818763 scopus 로고    scopus 로고
    • Endogenous beta-glucosidase and beta-galactosidase activities from selected probiotic micro-organisms and their role in isoflavone biotransformation in soymilk
    • Otieno, D. O., and Shah, N. P. (2007) Endogenous beta-glucosidase and beta-galactosidase activities from selected probiotic micro-organisms and their role in isoflavone biotransformation in soymilk. J. Appl. Microbiol. 103, 910–917
    • (2007) J. Appl. Microbiol. , vol.103 , pp. 910-917
    • Otieno, D.O.1    Shah, N.P.2
  • 30
    • 0032566518 scopus 로고    scopus 로고
    • Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity
    • Day, A. J., DuPont, M. S., Ridley, S., Rhodes, M., Rhodes, M. J., et al. (1998) Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity. FEBS Lett. 436, 71–75
    • (1998) FEBS Lett. , vol.436 , pp. 71-75
    • Day, A.J.1    DuPont, M.S.2    Ridley, S.3    Rhodes, M.4    Rhodes, M.J.5
  • 32
    • 80052629054 scopus 로고    scopus 로고
    • Stereospecific microbial production of isoflavanones from isoflavones and isoflavone glucosides
    • Park, H. Y., Kim, M., and Han, J. (2011) Stereospecific microbial production of isoflavanones from isoflavones and isoflavone glucosides. Appl. Microbiol. Biotechnol. 91, 1173–1181
    • (2011) Appl. Microbiol. Biotechnol. , vol.91 , pp. 1173-1181
    • Park, H.Y.1    Kim, M.2    Han, J.3
  • 33
    • 33847056543 scopus 로고    scopus 로고
    • Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces
    • Tamura, M., Tsushida, T., and Shinohara, K. (2007) Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces. Anaerobe. 13, 32–35
    • (2007) Anaerobe. , vol.13 , pp. 32-35
    • Tamura, M.1    Tsushida, T.2    Shinohara, K.3
  • 35
    • 0036278213 scopus 로고    scopus 로고
    • Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein
    • Hur, H. G., Beger, R. D., Heinze, T. M., Lay, J. O., Jr., Freeman, J. P., et al. (2002) Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein. Arch. Microbiol. 178, 8–12
    • (2002) Arch. Microbiol. , vol.178 , pp. 8-12
    • Hur, H.G.1    Beger, R.D.2    Heinze, T.M.3    Lay, J.O.4    Freeman, J.P.5
  • 36
    • 76749089496 scopus 로고    scopus 로고
    • Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces
    • Yokoyama, S., Niwa, T., Osawa, T., and Suzuki, T. (2010) Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Arch. Microbiol. 192, 15–22
    • (2010) Arch. Microbiol. , vol.192 , pp. 15-22
    • Yokoyama, S.1    Niwa, T.2    Osawa, T.3    Suzuki, T.4
  • 37
    • 0037022964 scopus 로고    scopus 로고
    • Anaerobic C-ring cleavage of genistein and daidzein by Eubacterium ramulus
    • Schoefer, L., Mohan, R., Braune, A., Birringer, M., and Blaut, M. (2002) Anaerobic C-ring cleavage of genistein and daidzein by Eubacterium ramulus. FEMS Microbiol. Lett. 208, 197–202
    • (2002) FEMS Microbiol. Lett. , vol.208 , pp. 197-202
    • Schoefer, L.1    Mohan, R.2    Braune, A.3    Birringer, M.4    Blaut, M.5
  • 38
    • 62149133476 scopus 로고    scopus 로고
    • Isolation of a human intestinal bacterium capable of daidzein and genistein conversion
    • Matthies, A., Blaut, M., and Braune, A. (2009) Isolation of a human intestinal bacterium capable of daidzein and genistein conversion. Appl. Environ. Microbiol. 75, 1740–1744
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 1740-1744
    • Matthies, A.1    Blaut, M.2    Braune, A.3
  • 39
    • 77952096064 scopus 로고    scopus 로고
    • Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS
    • Tsuji, H., Moriyama, K., Nomoto, K., Miyanaga, N., and Akaza, H. (2010) Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS. Arch Microbiol. 192, 279–287
    • (2010) Arch Microbiol. , vol.192 , pp. 279-287
    • Tsuji, H.1    Moriyama, K.2    Nomoto, K.3    Miyanaga, N.4    Akaza, H.5
  • 40
    • 49449095071 scopus 로고    scopus 로고
    • Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine
    • Matthies, A., Clavel, T., Gutschow, M., Engst, W., Haller, D., et al. (2008) Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine. Appl. Environ. Microbiol. 74, 4847–4852
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 4847-4852
    • Matthies, A.1    Clavel, T.2    Gutschow, M.3    Engst, W.4    Haller, D.5
  • 41
    • 2942590320 scopus 로고    scopus 로고
    • Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry
    • Prasain, J. K., Jones, K., Brissie, N., Moore, R., Wyss, J. M., et al. (2004) Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 52, 3708–3712
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 3708-3712
    • Prasain, J.K.1    Jones, K.2    Brissie, N.3    Moore, R.4    Wyss, J.M.5
  • 42
    • 84960088268 scopus 로고    scopus 로고
    • Pharmacokinetic profiles of the five isoflavonoids from Pueraria lobata roots in the CSF and plasma of rats
    • Xiao, B. X., Feng, L., Cao, F. R., Pan, R. L., Liao, Y. H., et al. (2016) Pharmacokinetic profiles of the five isoflavonoids from Pueraria lobata roots in the CSF and plasma of rats. J. Ethnopharmacol. 184, 22–29
    • (2016) J. Ethnopharmacol. , vol.184 , pp. 22-29
    • Xiao, B.X.1    Feng, L.2    Cao, F.R.3    Pan, R.L.4    Liao, Y.H.5
  • 43
    • 84963642512 scopus 로고    scopus 로고
    • Liquid chromatography with tandem mass spectrometry: a sensitive method for the determination of dehydrodiisoeugenol in rat cerebral nuclei
    • Zhang, Y. B., Yang, X. B., Yang, X. W., Xu, W., Li, F., et al. (2016) Liquid chromatography with tandem mass spectrometry: a sensitive method for the determination of dehydrodiisoeugenol in rat cerebral nuclei. Molecules. 21, 321
    • (2016) Molecules. , vol.21 , pp. 321
    • Zhang, Y.B.1    Yang, X.B.2    Yang, X.W.3    Xu, W.4    Li, F.5
  • 44
    • 35148862578 scopus 로고    scopus 로고
    • Isoflavones from soya foods are more bioavailable in children than adults
    • Halm, B. M., Ashburn, L. A., and Franke, A. A. (2007) Isoflavones from soya foods are more bioavailable in children than adults. Br. J. Nutr. 98, 998–1005
    • (2007) Br. J. Nutr. , vol.98 , pp. 998-1005
    • Halm, B.M.1    Ashburn, L.A.2    Franke, A.A.3
  • 45
    • 48049098727 scopus 로고    scopus 로고
    • Isoflavones in children and adults consuming soy
    • Franke, A. A., Halm, B. M., and Ashburn, L. A. (2008) Isoflavones in children and adults consuming soy. Arch. Biochem. Biophys. 476, 161–170
    • (2008) Arch. Biochem. Biophys. , vol.476 , pp. 161-170
    • Franke, A.A.1    Halm, B.M.2    Ashburn, L.A.3
  • 46
    • 84892558969 scopus 로고    scopus 로고
    • Daidzein promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and improves glucose homeostasis in Type 2 diabetic model mice
    • Cheong, S. H., Furuhashi, K., Ito, K., Nagaoka, M., Yonezawa, T., et al. (2014) Daidzein promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and improves glucose homeostasis in Type 2 diabetic model mice. J. Nutr. Biochem. 25, 136–143
    • (2014) J. Nutr. Biochem. , vol.25 , pp. 136-143
    • Cheong, S.H.1    Furuhashi, K.2    Ito, K.3    Nagaoka, M.4    Yonezawa, T.5
  • 47
    • 84878216551 scopus 로고    scopus 로고
    • Daidzein inhibits carbohydrate digestive enzymes in vitro and alleviates postprandial hyperglycemia in diabetic mice
    • Park, M. H., Ju, J. W., Park, M. J., and Han, J. S. (2013) Daidzein inhibits carbohydrate digestive enzymes in vitro and alleviates postprandial hyperglycemia in diabetic mice. Eur. J. Pharmacol. 712, 48–52
    • (2013) Eur. J. Pharmacol. , vol.712 , pp. 48-52
    • Park, M.H.1    Ju, J.W.2    Park, M.J.3    Han, J.S.4
  • 48
    • 84960532923 scopus 로고    scopus 로고
    • The dietary isoflavone daidzein reduces expression of pro-inflammatory genes through PPARalpha/gamma and JNK pathways in adipocyte and macrophage co-cultures
    • Sakamoto, Y., Kanatsu, J., Toh, M., Naka, A., Kondo, K., et al. (2016) The dietary isoflavone daidzein reduces expression of pro-inflammatory genes through PPARalpha/gamma and JNK pathways in adipocyte and macrophage co-cultures. PLoS One. 11, e0149676
    • (2016) PLoS One. , vol.11
    • Sakamoto, Y.1    Kanatsu, J.2    Toh, M.3    Naka, A.4    Kondo, K.5
  • 49
    • 84898753974 scopus 로고    scopus 로고
    • Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-alpha-stimulated murine lung epithelial cells via depressing PARP-1 activity
    • Li, H. Y., Pan, L., Ke, Y. S., Batnasan, E., Jin, X. Q., et al. (2014) Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-alpha-stimulated murine lung epithelial cells via depressing PARP-1 activity. Acta Pharmacol. Sin. 35, 496–503
    • (2014) Acta Pharmacol. Sin. , vol.35 , pp. 496-503
    • Li, H.Y.1    Pan, L.2    Ke, Y.S.3    Batnasan, E.4    Jin, X.Q.5
  • 50
    • 38749085618 scopus 로고    scopus 로고
    • Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice
    • Choi, M. S., Jung, U. J., Yeo, J., Kim, M. J., and Lee, M. K. (2008) Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice. Diabetes Metab. Res. Rev. 24, 74–81
    • (2008) Diabetes Metab. Res. Rev. , vol.24 , pp. 74-81
    • Choi, M.S.1    Jung, U.J.2    Yeo, J.3    Kim, M.J.4    Lee, M.K.5
  • 51
    • 33746591715 scopus 로고    scopus 로고
    • Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db mice
    • Ae Park, S., Choi, M. S., Cho, S. Y., Seo, J. S., Jung, U. J., et al. (2006) Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db mice. Life Sci. 79, 1207–1213
    • (2006) Life Sci. , vol.79 , pp. 1207-1213
    • Ae Park, S.1    Choi, M.S.2    Cho, S.Y.3    Seo, J.S.4    Jung, U.J.5
  • 52
    • 84872458311 scopus 로고    scopus 로고
    • Daidzein improves insulin resistance in ovariectomized rats
    • Cao, Y. K., Zhang, S. F., Zou, S. E., and Xia, X. (2013) Daidzein improves insulin resistance in ovariectomized rats. Climacteric. 16, 111–116
    • (2013) Climacteric. , vol.16 , pp. 111-116
    • Cao, Y.K.1    Zhang, S.F.2    Zou, S.E.3    Xia, X.4
  • 53
    • 84924529240 scopus 로고    scopus 로고
    • Anti-obese and anti-diabetic effects of a mixture of daidzin and glycitin on C57BL/6J mice fed with a high-fat diet
    • Zang, Y., Igarashi, K., and Yu, C. (2015) Anti-obese and anti-diabetic effects of a mixture of daidzin and glycitin on C57BL/6J mice fed with a high-fat diet. Biosci. Biotechnol. Biochem. 79, 117–123
    • (2015) Biosci. Biotechnol. Biochem. , vol.79 , pp. 117-123
    • Zang, Y.1    Igarashi, K.2    Yu, C.3
  • 54
    • 27744536731 scopus 로고    scopus 로고
    • Contrasting effects of puerarin and daidzin on glucose homeostasis in mice
    • Meezan, E., Meezan, E. M., Jones, K., Moore, R., Barnes, S., et al. (2005) Contrasting effects of puerarin and daidzin on glucose homeostasis in mice. J. Agric. Food Chem. 53, 8760–8767
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 8760-8767
    • Meezan, E.1    Meezan, E.M.2    Jones, K.3    Moore, R.4    Barnes, S.5
  • 55
    • 84872903377 scopus 로고    scopus 로고
    • Effects of natural S-equol supplements on overweight or obesity and metabolic syndrome in the Japanese, based on sex and equol status
    • Usui, T., Tochiya, M., Sasaki, Y., Muranaka, K., Yamakage, H., et al. (2013) Effects of natural S-equol supplements on overweight or obesity and metabolic syndrome in the Japanese, based on sex and equol status. Clin. Endocrinol (Oxf). 78, 365–372
    • (2013) Clin. Endocrinol (Oxf). , vol.78 , pp. 365-372
    • Usui, T.1    Tochiya, M.2    Sasaki, Y.3    Muranaka, K.4    Yamakage, H.5
  • 56
    • 84894245720 scopus 로고    scopus 로고
    • Urinary isoflavone concentrations are inversely associated with cardiometabolic risk markers in pregnant U.S. women
    • Shi, L., Ryan, H. H., Jones, E., Simas, T. A., Lichtenstein, A. H., et al. (2014) Urinary isoflavone concentrations are inversely associated with cardiometabolic risk markers in pregnant U.S. women. J. Nutr. 144, 344–351
    • (2014) J. Nutr. , vol.144 , pp. 344-351
    • Shi, L.1    Ryan, H.H.2    Jones, E.3    Simas, T.A.4    Lichtenstein, A.H.5
  • 57
    • 84860800470 scopus 로고    scopus 로고
    • Novel soy germ pasta improves endothelial function, blood pressure, and oxidative stress in patients with type 2 diabetes
    • Clerici, C., Nardi, E., Battezzati, P. M., Asciutti, S., Castellani, D., et al. (2011) Novel soy germ pasta improves endothelial function, blood pressure, and oxidative stress in patients with type 2 diabetes. Diabetes Care. 34, 1946–1948
    • (2011) Diabetes Care. , vol.34 , pp. 1946-1948
    • Clerici, C.1    Nardi, E.2    Battezzati, P.M.3    Asciutti, S.4    Castellani, D.5
  • 58
    • 0031771536 scopus 로고    scopus 로고
    • Effects of soy protein on renal function and proteinuria in patients with type 2 diabetes
    • Anderson, J. W., Blake, J. E., Turner, J., and Smith, B. M. (1998) Effects of soy protein on renal function and proteinuria in patients with type 2 diabetes. Am. J. Clin. Nutr. 68, 1347S–1353S
    • (1998) Am. J. Clin. Nutr. , vol.68 , pp. 1347S-1353S
    • Anderson, J.W.1    Blake, J.E.2    Turner, J.3    Smith, B.M.4
  • 59
    • 48649098937 scopus 로고    scopus 로고
    • Soy protein intake, cardiorenal indices, and C-reactive protein in type 2 diabetes with nephropathy: a longitudinal randomized clinical trial
    • Azadbakht, L., Atabak, S., and Esmaillzadeh, A. (2008) Soy protein intake, cardiorenal indices, and C-reactive protein in type 2 diabetes with nephropathy: a longitudinal randomized clinical trial. Diabetes Care. 31, 648–654
    • (2008) Diabetes Care. , vol.31 , pp. 648-654
    • Azadbakht, L.1    Atabak, S.2    Esmaillzadeh, A.3
  • 60
    • 3543140665 scopus 로고    scopus 로고
    • Isolated soy protein consumption reduces urinary albumin excretion and improves the serum lipid profile in men with type 2 diabetes mellitus and nephropathy
    • Teixeira, S. R., Tappenden, K. A., Carson, L., Jones, R., Prabhudesai, M., et al. (2004) Isolated soy protein consumption reduces urinary albumin excretion and improves the serum lipid profile in men with type 2 diabetes mellitus and nephropathy. J. Nutr. 134, 1874–1880
    • (2004) J. Nutr. , vol.134 , pp. 1874-1880
    • Teixeira, S.R.1    Tappenden, K.A.2    Carson, L.3    Jones, R.4    Prabhudesai, M.5
  • 61
    • 69549086427 scopus 로고    scopus 로고
    • Soy protein reduces serum LDL cholesterol and the LDL cholesterol:HDL cholesterol and apolipoprotein B:apolipoprotein A-I ratios in adults with type 2 diabetes
    • Pipe, E. A., Gobert, C. P., Capes, S. E., Darlington, G. A., Lampe, J. W., et al. (2009) Soy protein reduces serum LDL cholesterol and the LDL cholesterol:HDL cholesterol and apolipoprotein B:apolipoprotein A-I ratios in adults with type 2 diabetes. J. Nutr. 139, 1700–1706
    • (2009) J. Nutr. , vol.139 , pp. 1700-1706
    • Pipe, E.A.1    Gobert, C.P.2    Capes, S.E.3    Darlington, G.A.4    Lampe, J.W.5
  • 62
    • 85030653116 scopus 로고    scopus 로고
    • Soyfood and isoflavone intake and risk of type 2 diabetes in Vietnamese adults
    • Nguyen, C. T., Pham, N. M., Do, V. V., Binns, C. W., Hoang, V. M., et al. (2017) Soyfood and isoflavone intake and risk of type 2 diabetes in Vietnamese adults. Eur. J. Clin. Nutr. 71, 1186–1192
    • (2017) Eur. J. Clin. Nutr. , vol.71 , pp. 1186-1192
    • Nguyen, C.T.1    Pham, N.M.2    Do, V.V.3    Binns, C.W.4    Hoang, V.M.5
  • 63
    • 34948816560 scopus 로고    scopus 로고
    • Soy isoflavone supplementation and fasting serum glucose and lipid profile among postmenopausal Chinese women: a double-blind, randomized, placebo-controlled trial
    • Ho, S. C., Chen, Y. M., Ho, S. S., and Woo, J. L. (2007) Soy isoflavone supplementation and fasting serum glucose and lipid profile among postmenopausal Chinese women: a double-blind, randomized, placebo-controlled trial. Menopause. 14, 905–912
    • (2007) Menopause. , vol.14 , pp. 905-912
    • Ho, S.C.1    Chen, Y.M.2    Ho, S.S.3    Woo, J.L.4
  • 64
    • 38149077344 scopus 로고    scopus 로고
    • Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study
    • Villegas, R., Gao, Y. T., Yang, G., Li, H. L., Elasy, T. A., et al. (2008) Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study. Am. J. Clin. Nutr. 87, 162–167
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 162-167
    • Villegas, R.1    Gao, Y.T.2    Yang, G.3    Li, H.L.4    Elasy, T.A.5
  • 65
    • 84922706350 scopus 로고    scopus 로고
    • Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: a double-blind, randomized, placebo-controlled trial
    • Ye, Y. B., Chen, A. L., Lu, W., Zhuo, S. Y., Liu, J., et al. (2015) Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: a double-blind, randomized, placebo-controlled trial. Mol. Nutr. Food Res. 59, 240–249
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 240-249
    • Ye, Y.B.1    Chen, A.L.2    Lu, W.3    Zhuo, S.Y.4    Liu, J.5
  • 66
    • 80052994194 scopus 로고    scopus 로고
    • Effects of soya isoflavones and exercise on body composition and clinical risk factors of cardiovascular diseases in overweight postmenopausal women: a 6-month double-blind controlled trial
    • Choquette, S., Riesco, E., Cormier, E., Dion, T., Aubertin-Leheudre, M., et al. (2011) Effects of soya isoflavones and exercise on body composition and clinical risk factors of cardiovascular diseases in overweight postmenopausal women: a 6-month double-blind controlled trial. Br. J. Nutr. 105, 1199–1209
    • (2011) Br. J. Nutr. , vol.105 , pp. 1199-1209
    • Choquette, S.1    Riesco, E.2    Cormier, E.3    Dion, T.4    Aubertin-Leheudre, M.5
  • 68
    • 0037732481 scopus 로고    scopus 로고
    • The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones
    • Arner, P. (2003) The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones. Trends Endocrinol. Metab. 14, 137–145
    • (2003) Trends Endocrinol. Metab. , vol.14 , pp. 137-145
    • Arner, P.1
  • 69
    • 84976902195 scopus 로고    scopus 로고
    • Lipid profile abnormalities seen in T2DM patients in primary healthcare in Turkey: a cross-sectional study
    • Ozder, A. (2014) Lipid profile abnormalities seen in T2DM patients in primary healthcare in Turkey: a cross-sectional study. Lipids Health Dis. 13, 183
    • (2014) Lipids Health Dis. , vol.13 , pp. 183
    • Ozder, A.1
  • 70
    • 85055459409 scopus 로고    scopus 로고
    • Alteration by dietary soy isoflavone of SERBP-1-dependent genes in the liver of rats fed a high saturated-fat diet
    • Yoko Takahashi, T. I. (2007) Alteration by dietary soy isoflavone of SERBP-1-dependent genes in the liver of rats fed a high saturated-fat diet. Rep. Nat'l. Food Res. Inst. 71, 7–13
    • (2007) Rep. Nat'l. Food Res. Inst. , vol.71 , pp. 7-13
    • Yoko Takahashi, T.I.1
  • 71
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • Shoelson, S. E., Lee, J., and Goldfine, A. B. (2006) Inflammation and insulin resistance. J. Clin. Invest. 116, 1793–1801
    • (2006) J. Clin. Invest. , vol.116 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 72
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • Wellen, K. E., and Hotamisligil, G. S. (2003) Obesity-induced inflammatory changes in adipose tissue. J. Clin. Invest. 112, 1785–1788
    • (2003) J. Clin. Invest. , vol.112 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 73
    • 84969296935 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease: epidemiology, biological mechanisms, treatment recommendations and future research
    • Leon, B. M., and Maddox, T. M. (2015) Diabetes and cardiovascular disease: epidemiology, biological mechanisms, treatment recommendations and future research. World J. Diabetes. 6, 1246–1258
    • (2015) World J. Diabetes. , vol.6 , pp. 1246-1258
    • Leon, B.M.1    Maddox, T.M.2
  • 74
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
    • Hotamisligil, G. S., Shargill, N. S., and Spiegelman, B. M. (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 259, 87–91
    • (1993) Science. , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 75
    • 84897100850 scopus 로고    scopus 로고
    • Daidzein regulates proinflammatory adipokines thereby improving obesity-related inflammation through PPARgamma
    • Sakamoto, Y., Naka, A., Ohara, N., Kondo, K., and Iida, K. (2014) Daidzein regulates proinflammatory adipokines thereby improving obesity-related inflammation through PPARgamma. Mol. Nutr. Food Res. 58, 718–726
    • (2014) Mol. Nutr. Food Res. , vol.58 , pp. 718-726
    • Sakamoto, Y.1    Naka, A.2    Ohara, N.3    Kondo, K.4    Iida, K.5


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