Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity

Acta Pharmacologica Sinica

Volumn 35, Issue 4, 2014, Pages 496-503

  Li, Hai Yan ^a,c   Pan, Lang ^b   Ke, Yue Shuang ^b   Batnasan, Enkhzaya ^b   Jin, Xiang Qun ^a   Liu, Zhong Ying ^a   Ba, Xue Qing ^b  

^a JILIN UNIVERSITY   (China)

^b NORTHEAST NORMAL UNIVERSITY   (China)

^c CHANGCHUN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Chemokine; Cxcl2; Daidzein; Inflammation; Isoflavone; Lung; NF B; PARP 1; Poly adenosine diphosphate ribosylation; TNF

Indexed keywords

CXCL2 CHEMOKINE; DAIDZEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CXCL2 PROTEIN, MOUSE; ENZYME INHIBITOR; ISOFLAVONE DERIVATIVE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; RELA PROTEIN, MOUSE; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASSAY; DRUG MECHANISM; DUAL REPORTER ASSAY; LUNG ALVEOLUS EPITHELIUM; MALE; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; DISEASE MODEL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; EPITHELIUM CELL; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; REPORTER GENE; SIGNAL TRANSDUCTION; TIME;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CHEMOKINE CXCL2; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; EPITHELIAL CELLS; GENES, REPORTER; ISOFLAVONES; LUNG; MALE; MICE, INBRED C57BL; PNEUMONIA; POLY(ADP-RIBOSE) POLYMERASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84898753974     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.191     Document Type: Article

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