Apoptotic mechanisms for neuronal cells in early brain injury after subarachnoid hemorrhage

Acta Neurochirurgica, Supplementum

Volumn 110, Issue , 2011, Pages 43-48

  Hasegawa, Yu ^a   Suzuki, Hidenori ^a   Sozen, Takumi ^a   Altay, Orhan ^a   Zhang, John H ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Cerebral blood flow; Early brain injury; Intracranial pressure; Subarachnoid hemorrhage

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; GLYCOGEN SYNTHASE KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; BLOOD CLOT; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN INJURY; BRAIN VASOSPASM; CONFERENCE PAPER; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; ENZYME ACTIVATION; HIPPOCAMPUS; HUMAN; INTRACRANIAL PRESSURE; LIPID PEROXIDATION; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; SUBARACHNOID HEMORRHAGE; SUBARACHNOID SPACE; SYSTEMATIC REVIEW; TUMOR SUPPRESSOR GENE;

EID: 85052609130     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0353-1_8     Document Type: Conference Paper

References (74)

1. Huang J, van Gelder JM. The probability of sudden death from rupture of intracranial aneurysms: A meta-analysis. Neurosurgery 2002;51:1101-5.
2. O'Hare TH. Subarachnoid hemorrhage: A review. J Emerg Med. 1987;5:135-44
3. Tseng MY, Czosnyka M, Richards H, Pickard JD, Kirkpatrick PJ. Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: A phase II randomized placebo-controlled trial. Stroke 2005;36:1627-32.
4. Schievink WI, Riedinger M, Jhutty TK, Simon P. Racial disparities in subarachnoid hemorrhage mortality: Los Angeles County, California, 1985-1998. Neuroepidemiology 2004;23:299-305.
5. Nau R, Haase S, Bunkowski S, Brück W. Neuronal apoptosis in the dentate gyrus in humans with subarachnoid hemorrhage and cerebral hypoxia. Brain Pathol. 2002;12:329-36.
6. Prunell GF, Mathiesen T, Diemer NH, Svendgaard NA. Experimental subarachnoid hemorrhage: Subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models. Neurosurgery 2003;52:165-75.
7. Bederson JB, Germano IM, Guarino L. Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat. Stroke 1995;26:1086-91.
8. Schwartz AY, Masago A, Sehba FA, Bederson JB. Experimental models of subarachnoid hemorrhage in the rat: A refinement of the endovascular filament model. J Neurosci Methods. 2000;96:161-7.
9. Veelken JA, Laing RJ, Jakubowski J. The Sheffield model of subarachnoid hemorrhage in rats. Stroke 1995;26:1279-833
10. Török E, Klopotowski M, Trabold R, Thal SC, Plesnila N, Schöller K. Mild hypothermia (33 degrees C) reduces intracranial hypertension and improves functional outcome after subarachnoid hemorrhage in rats. Neurosurgery 2009;65:352-9.
11. Bederson JB, Levy AL, Ding WH, Kahn R, DiPerna CA, Jenkins AL III et al. Acute vasoconstriction after subarachnoid hemorrhage. Neurosurgery 1998;42:352-62.
12. Park S, Yamaguchi M, Zhou C, Calvert JW, Tang J, Zhang JH. Neurovascular protection reduces early brain injury after subarachnoid hemorrhage. Stroke 2004;35:2412-7.
13. Matz PG, Copin JC, Chan PH. Cell death after exposure to subarachnoid hemolysate correlates inversely with expression of CuZn-superoxide dismutase. Stroke 2000;31:2450-9.
14. Endo H, Nito C, Kamada H, Yu F, Chan PH. Akt/GSK3beta survival signaling is involved in acute brain injury after subarachnoid hemorrhage in rats. Stroke 2006;37:2140-6.
15. Xi G, Keep RF, Hoff JT. Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J Neurosurg. 1998;89:991-6.
16. Matz PG, Fujimura M, Chan PH. Subarachnoid hemolysate produces DNA fragmentation in a pattern similar to apoptosis in mouse brain. Brain Res. 2000;858:312-9.
17. Matz PG, Fujimura M, Lewen A, Morita-Fujimura Y, Chan PH. Increased cytochrome c-mediated DNA fragmentation and cell death in manganese-superoxide dismutase-deficient mice after exposure to subarachnoid hemolysate. Stroke 2001;32:506-15.
18. Kimura H, Gules I, Meguro T, Zhang JH. Cytotoxicity of cytokines in cerebral microvascular endothelial cell. Brain Res. 2003; 990:148-56.
19. Meguro T, Klett CP, Chen B, Parent AD, Zhang JH. Role of calcium channels in oxyhemoglobin-induced apoptosis in endothelial cells. J Neurosurg. 2000;93:640-6.
20. Ogihara K, Zubkov AY, Bernanke DH, Lewis AI, Parent AD, Zhang JH. Oxyhemoglobin-induced apoptosis in cultured endothelial cells. J Neurosurg. 1999;91:459-65.
21. Bazán NG, Rodríguez de Turco EB. Membrane lipids in the pathogenesis of brain edema: phospholipids and arachidonic acid, the earliest membrane components changed at the onset of ischemia. Adv Neurol. 1980;28:197-205.
22. Gules I, Satoh M, Nanda A, Zhang JH. Apoptosis, blood-brain barrier, and subarachnoid hemorrhage. Acta Neurochir Suppl. 2003;86:483-7.
23. Chan PH. Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia. Neurochem Res. 2004;29:1943-9.
24. Cheng G, Wei L, Zhi-Dan S, Shi-Guang Z, Xiang-Zhen L. Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway. BMC Neurosci. 2009; doi:10,1186/14712202107.
25. Yan J, Chen C, Hu Q, Yang X, Lei J, Yang Let al., The role of p53 in brain edema after 24 h of experimental subarachnoid hemorrhage in a rat model. Exp Neurol. 2008;214:37-46.
26. Zhang F, Yin W, Chen J. Apoptosis in cerebral ischemia: Executional and regulatory signaling mechanisms. Neurol Res. 2004; 26:835-45.
27. Hemmings BA. Akt signaling: Linking membrane events to life and death decisions. Science 1997;275:628-30.
28. Pugazhenthi S, Nesterova A, Sable C, Heidenreich KA, Boxer LM, Heasley LE et al. Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. J Biol Chem. 2000;275:10761-6.
29. Hasegawa Y, Hamada J, Morioka M, Yano S, Kawano T, Kai Yet al., Neuroprotective effect of postischemic administration of sodium orthovanadate in rats with transient middle cerebral artery occlusion. J Cereb Blood Flow Metab. 2003;23:1040-51.
30. Hasegawa Y, Morioka M, Hasegawa S, Matsumoto J, Kawano T, Kai Y et al. Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats. J Pharmacol Exp Ther. 2006;317:875-81.
31. Shioda N, Ishigami T, Han F, Moriguchi S, Shibuya M, Iwabuchi Y et al. Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia. Neuroscience 2007;148:221-9.
32. Endo H, Nito C, Kamada H, Yu F, Chan PH. Reduction in oxidative stress by superoxide dismutase overexpression attenuates acute brain injury after subarachnoid hemorrhage via activation of Akt/glycogen synthase kinase-3beta survival signaling. J Cereb Blood Flow Metab. 2007;27:975-82.
33. Kusaka G, Ishikawa M, Nanda A, Granger DN, Zhang JH. Signaling pathways for early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2004;24:916-25.
34. Irving EA, Bamford M. Role of mitogen- and stress-activated kinases in ischemic injury. J Cereb Blood Flow Metab. 2002; 22:631-47.
35. Chakraborti S, Chakraborti T. Oxidant-mediated activation of mitogen-activated protein kinases and nuclear transcription factors in the cardiovascular system: A brief overview. Cell Signal. 1988;10:675-83.
36. Chow J, Ogunshola O, Fan SY, Li Y, Ment LR, Madri JA. Astrocyte-derived VEGF mediates survival and tube stabilization of hypoxic brain microvascular endothelial cells in vitro. Brain Res Dev Brain Res. 2001;130:123-32.
37. Parker LC, Luheshi GN, Rothwell NJ, Pinteaux E. IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice. Br J Pharmacol. 2002;136:312-20.
38. Sugden PH, Clerk A. ''Stress-responsive'' mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res. 1998;83:345-52.
39. Sozen T, Tsuchiyama R, Hasegawa Y, Suzuki H, Jadhav V, Nishizawa Set al., Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice. Stroke 2009;40:2519-25.
40. Yatsushige H, Ostrowski RP, Tsubokawa T, Colohan A, Zhang JH. Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage. J Neurosci Res. 2007;85:1436-48.
41. Sawe N, Steinberg G, Zhao H. Dual roles of theMAPK/ERK1/2 cell signaling pathway after stroke. J Neurosci Res. 2008;86:1659-69.
42. Fassbender K, Hodapp B, Rossol S, Bertsch T, Schmeck J, Schütt Set al., Inflammatory cytokines in subarachnoid haemorrhage: Association with abnormal blood flow velocities in basal cerebral arteries. J Neurol Neurosurg Psychiatry. 2001;70:534-7.
43. Hirashima Y, Nakamura S, Endo S, Kuwayama N, Naruse Y, Takaku A. Elevation of platelet activating factor, inflammatory cytokines, and coagulation factors in the internal jugular vein of patients with subarachnoid hemorrhage. Neurochem Res. 1997;22:1249-55.
44. Kuan CY, Whitmarsh AJ, Yang DD, Liao G, Schloemer AJ, Dong Cet al., A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci USA. 2003;100:15184-9.
45. Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000;407:802-9.
46. Harada S, Kamiya K, Masago A, Iwata A, Yamada K. Subarachnoid hemorrhage induces c-fos, c-jun and hsp70 mRNA expression in rat brain. Neuroreport 1997;8:3399-404.
47. Kawamura Y, Yamada K, Masago A, Katano H, Matsumoto T, Mase M. Hypothermia modulates induction of hsp70 and c-jun mRNA in the rat brain after subarachnoid hemorrhage. J Neurotrauma. 2000;17:243-50.
48. Cheng A, Chan SL, Milhavet O, Wang S, Mattson MP. p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells. J Biol Chem. 2001;276:43320-7.
49. Nito C, Kamada H, Endo H, Niizuma K, Myer DJ, Chan PH. Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion. J Cereb Blood Flow Metab. 2008;28:1686-96.
50. Elmore S. Apoptosis: A review of programmed cell death. Toxicol Pathol. 2007;35:495-516.
51. Cho BB, Toledo-Pereyra LH. Caspase-independent programmed cell death following ischemic stroke. J Invest Surg. 2008;21:141-7.
52. Li X, Nemoto M, Xu Z, Yu SW, Shimoji M, Andrabi SA, et al. Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus. Neuroscience 2007;144:56-65.
53. Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJet al., Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002;297:200-1.
54. Loh KP, Huang SH, De Silva R, Tan BK, Zhu YZ. Oxidative stress: Apoptosis in neuronal injury. Curr Alzheimer Res. 2006;3:327-37.
55. Sugawara T, Chan PH. Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia. Antioxid Redox Signal. 2003;5:597-607.
56. Ayer RE, Zhang JH. Oxidative stress in subarachnoid haemorrhage: Significance in acute brain injury and vasospasm. Acta Neurochir Suppl. 2008;104:33-41.
57. Asano T. Oxyhemoglobin as the principal cause of cerebral vasospasm: A holistic view of its actions. Crit Rev Neurosurg. 1999;9:303-18.
58. Gaetani P, Lombardi D. Brain damage following subarachnoid hemorrhage: The imbalance between anti-oxidant systems and lipid peroxidative processes. J Neurosurg Sci. 1992;36:1-10.
59. Kaynar MY, Tanriverdi T, Kemerdere R, Atukeren P, Gumustas K. Cerebrospinal fluid superoxide dismutase and serum malondialdehyde levels in patients with aneurysmal subarachnoid hemorrhage: preliminary results. Neurol Res. 2005;27:562-7.
60. Fridman JS, Lowe SW. Control of apoptosis by p53. Oncogene 2003;22:9030-40.
61. Culmsee C, Mattson MP. p53 in neuronal apoptosis. Biochem Biophys Res Commun. 2005;331:761-77.
62. Cahill J, Calvert JW, Marcantonio S, Zhang JH. p53 may play an orchestrating role in apoptotic cell death after experimental subarachnoid hemorrhage. Neurosurgery 2007;60:531-455
63. Gao C, Liu X, Liu W, Shi H, Zhao Z, Chen Het al., Antiapoptotic and neuroprotective effects of Tetramethylpyrazine following subarachnoid hemorrhage in rats. Auton Neurosci. 2008;141:22-30.
64. Martin-Villalba A, Herr I, Jeremias I, Hahne M, Brandt R, Vogel J et al. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factorrelated apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J Neurosci. 1999;19:3809-17.
65. Rosenbaum DM, Gupta G, D'Amore J, Singh M, Weidenheim K, Zhang Het al., Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia. J Neurosci Res. 2000;61: 686-92.
66. Yuan J, Horvitz HR. A first insight into the molecular mechanisms of apoptosis. Cell 2004;116(Suppl):53-66
67. Kawano T, Morioka M, Yano S, Hamada J, Ushio Y, Miyamoto E et al. Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus. J Cereb Blood Flow Metab. 2002;22:926-34.
68. Ma CX, Yin WN, Cai BW, He M, Wu J, Wang JY, et al. Activation of TLR4/NF-kappaB signaling pathway in early brain injury after subarachnoid hemorrhage. Neurol Res. doi:10,1179/016164109x12445616596283.
69. Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005;25:554-71.
70. Ostrowski RP, Tang J, Zhang JH. Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model. Stroke 2006;37:1314-8.
71. Sugawara T, Jadhav V, Ayer R, Chen W, Suzuki H, Zhang JH. Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. Stroke 2009;40:1530-2.
72. Ersahin M, Toklu HZ, Cetinel S, Yüksel M, Yegen BC, Sener G. Melatonin reduces experimental subarachnoid hemorrhage-induced oxidative brain damage and neurological symptoms. J Pineal Res. 2009;46:324-32.
73. Lu H, Zhang DM, Chen HL, Lin YX, Hang CH, Yin HX, et al. N-acetylcysteine suppresses oxidative stress in experimental rats with subarachnoid hemorrhage. J Clin Neurosci. 2009;16:684-8.
74. Lin CL, Dumont AS, Tsai YJ, Huang JH, Chang KP, Kwan AL, et al. 17beta-estradiol activates adenosine A(2a) receptor after subarachnoid hemorrhage. J Surg Res. doi:10,3171/20093JNS081660.