Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats

Stroke

Volumn 40, Issue 4, 2009, Pages 1530-1532

  Sugawara, Takashi ^a,c   Jadhav, Vikram ^a   Ayer, Robert ^a   Chen, Wanqiu ^a   Suzuki, Hidenori ^a   Zhang, John H ^a,b,d  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

^c Section of Neurosurgery   (Japan)

^d LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Argatroban; Brain edema; Early brain injury; Subarachnoid hemorrhage; Thrombin

Indexed keywords

ARGATROBAN; THROMBIN; ANTICOAGULANT AGENT; PIPECOLIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURY; CONTROLLED STUDY; DRUG DOSE COMPARISON; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBARACHNOID HEMORRHAGE; ANIMAL; BLOOD; CELL DEATH; CONVALESCENCE; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; MOTOR ACTIVITY; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTICOAGULANTS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CELL DEATH; DISEASE MODELS, ANIMAL; MALE; MOTOR ACTIVITY; PIPECOLIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SUBARACHNOID HEMORRHAGE; THROMBIN;

EID: 65249125759     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.531699     Document Type: Article

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