Advances in experimental subarachnoid hemorrhage

Acta Neurochirurgica, Supplementum

Volumn 110, Issue , 2011, Pages 15-21

  Zhou, Yilin ^a   Martin, Robert D ^a   Zhang, John H ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral vasospasm (CVS); Early brain injury (EBI); Subarachnoid hemorrhage (SAH)

Indexed keywords

ARGATROBAN; CYCLIC GMP; ENDOTHELIN; ESTRADIOL BENZOATE; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; HYPOXIA INDUCIBLE FACTOR 1; JANUS KINASE 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; STAT3 PROTEIN; STATIN (PROTEIN); THROMBIN;

APOPTOSIS; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN VASOSPASM; CONFERENCE PAPER; ENDOTHELIUM; ENZYME ACTIVITY; HUMAN; INFLAMMATION; MEDICAL RESEARCH; MORBIDITY; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; UPREGULATION; VASODILATATION;

EID: 85052608852     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0353-1_3     Document Type: Conference Paper

References (76)

1. Ansar S, Vikman P, Nielsen M, Edvinsson L. Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage. Am J Physiol Heart Circ Physiol. 2007;293(6):H3750-8.
2. Ayer RE, Zhang JH. Oxidative stress in subarachnoid haemorrhage: Significance in acute brain injury and vasospasm. Acta Neurochir Suppl. 2008;104:33-41.
3. Baranova O, Miranda LF, Pichiule P, Dragatsis I, Johnson RS, Chavez JC. Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J Neurosci. 2007;27:6320-32.
4. Barbosa MD, Arthur AS, Louis RH, MacDonald T, Polin RS, Gazak C, et al. The novel 5-lipoxygenase inhibitor ABT-761 attenuates cerebral vasospasm in a rabbit model of subarachnoid hemorrhage. Neurosurgery 2001;49:1205-12.
5. Bederson JB, Germano IM, Guarino L. Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat. Stroke 1995; 26:1086-91.
6. Bowman G, Bonneau RH, Chinchilli VM, Tracey KJ, Cockroft KM. A novel inhibitor of inflammatory production (CNI-1493) reduces rodent post-hemorrhagic vasospasm. Neurocrit Care. 2006;5(3): 22209.
7. Broderick JP, Brott TJ, Duldner JE, Tomsick T, Leach A. Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 1994;25:1342-7.
8. Cahill J, Zhang JH. Subarachnoid hemorrhage: Is it time for a new direction? Stroke 2009;40(suppl 1):S86-7.
9. Cahill J, Calvert JW, Solaroglu I, Zhang JH. Vasospasm and p53-induced apoptosis in an experimental model of subarachnoid hemorrhage. Stroke 2006;37(7):1868-74.
10. Cahill WJ, Calvert JH, Zhang JH. Mechanisms of early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2006;26:1341-53.
11. Che X, Ye W, Panga L, Wu DC, Yang GY. Monocyte chemoattractant protein-1 expressed in neurons and astrocytes during focal ischemia in mice. Brain Res. 2001;902(2):171-7.
12. Chen G, Wu J, Sun C, Qi M, Hang C, Gong Y, et al. Potential role of JAK2 in cerebral vasospasm after experimental subarachnoid hemorrhage. Brain Res. 2008;1214:136-44.
13. Chen G, Zhang S, Shi J, Ai J, Hang C. Effects of recombinant human erythropoietin (rhEPO) on the JAK2/STAT3 pathway and endothelial apoptosis in the rabbit basilar artery after subarachnoid hemorrhage. Cytokine 2009;45(3):162-8.
14. Chen W, Ostrowski RP, Obenaus A, Zhang JH. Prodeath or prosurvival: Two facets of hypoxia inducible factor-1 in perinatal brain injury. Exp Neurol. 2009;216(1):7-15.
15. Cheng G, Wei L, Zhi-Dan S, Shi-Guang Z, Xiang-Zhen L. Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway. BMC Neurosci. 2009;10:7.
16. Dietrich HH, Dacey RG Jr. Molecular keys to the problems of cerebral vasospasm. Neurosurgery 2000;46(3):517-30.
17. Dorsch NW. Cerebral arterial spasm-a clinical review. Br J Neurosurg. 1995;9:403-12.
18. Dumont AS, Dumont RJ, Chow MM, Lin CL, Calisaneller T, Ley KF, et al. Cerebral vasospasm after subarachnoid hemorrhage: putative role of inflammation. Neurosurgery 2003;53(1):123-33.
19. Endo H, Nito C, Kamada H, Yu F, Chan PH. Reduction in oxidative stress by superoxide dismutase overexpression attenuates acute brain injury after subarachnoid hemorrhage via activation of Akt/glycogen synthase kinase-3beta survival signaling. J Cereb Blood Flow Metab. 2007;27(5):975-82.
20. Ersahin M, Toklu HZ, Cetinel S, Yuksel M, Yegen BC, Sener G. Melatonin reduces experimental subarachnoid hemorrhage-induced oxidative brain damage and neurological symptoms. J Pineal Res. 2009;46(3):324-32.
21. Frykholm P, Andersson JL, Langstrom B, Persson L, Enbald P. Haemodynamic and metabolic disturbances in the acute stage of subarachnoid haemorrhage demonstrated by PET. Acta Neural Scand. 2004;109:25-32.
22. Helton R, Cui J, Scheele JR, Ellison JA, Ames C, Gibson C, et al. Brain-specific knock-out of hypoxia-inducible factor-1 alpha reduces rather than increases hypoxic-ischemic damage. J Neurosci. 2005;25:4099-107.
23. Hijdra A, Braakman R, van Gijn J, Vermeulen M, van Crevel H. Aneurysmal subarachnoid hemorrhage. Complications and outcome in a hospital population. Stroke 1987;18(6):1061-7.
24. Hirano K, Kanaide H. Role of proteinase-activated receptors in the vascular system. J Atheroscler Thromb. 2003;10:211-25.
25. Hishikawa T, Ono S, Ogawa T, Tokunage K, Sugiu K, Date I. Effects of deferoxamine-activated hypoxia-inducible factor-1 on the brainstem after subarachnoid hemorrhage in rats. Neurosurgery 2008;62(1):232-40.
26. Horky LL, Pluta RM, Boock RJ, Oldfield EH. Role of ferrous iron chelator 2,2'-dipyridyl in preventing delayed vasospasm in a primate model of subarachnoid hemorrhage. J Neurosurg. 1998; 88:298-303.
27. Iseda K, Ono S, Onoda K, Satoh M, Manabe H, Nishiguchi M, et al. Antivasospastic and antiinflammatory effects of caspase inhibitor in experimental subarachnoid hemorrhage. J Neurosurg. 2007;107 (1):128-35.
28. Jiang Y, Wu J, Keep RF, Hua Y, Hoff JT, Xi G. Hypoxiainducible factor-1a accumulation in the brain after experimental intracerebral hemorrhage. J Cereb Blood Flow Metab. 2002;22: L689-96.
29. Kai Y, Hirano K, Maeda Y, Nishimura J, Sasaki T, Kanaide H. Prevention of the hypercontractile to thrombin by proteinase-activated receptor 1 antagonist in subarachnoid hemorrhage. Stroke 2007;38:3259-65.
30. Karaoglan A, Akdemir O, Barut S, Kokturk S, Uzun H, Tasyurekli M, et al. The effect of resveratrol on vasospasm after experimental subarachnoid hemorrhage in rats. Surg Neurol. 2008;70(4):337-43.
31. Kasuya H, Shimizu T, Takakura K. Thrombin activity in CSF after SAH is correlated with the degree of SAH the persistence of subarachnoid clot and the development vasospasm. Acta Neurochir (Wien). 1998;140(6):579-84.
32. Kitaoka T, Hua Y, Xi G, Hoff JT, Keep RF. Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage. Stroke 2002;33(12):3012-8.
33. Kreiter KT, Copeland D, Bernardini GL, Bates JE, Peery S, Claassen J, et al. Predictors of cognitive dysfunction after subarachnoid hemorrhage. Stroke 2002;33:200-8.
34. Kumagai N, Chiba Y, Hosono M, Fujii M, Kawamura N, Keino H, et al. Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse. Brain Res. 2007;1185:75-85.
35. Kusaka G, Ishikawa M, Nanda A, Granger DN, Zhang JH. Signaling pathways for early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2004;24:916-25.
36. Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Bio Chem. 1998;273(37):24266-71.
37. Lewen A, Matz P, Chan PH. Free radical pathways in CNS injury. J Neurotrauma. 2000;17:871-90.
38. Lin CL, Shih HC, Dumont AS, Kassell NF, Lieu AS, Su YF, et al. The effect of 17beta-estradiol in attenuating experimental subarachnoid hemorrhage-induced cerebral vasospasm. J Neurosurg. 2006; 104(2):298-304.
39. Linn FH, Rinkel GJ, Algra A, Van Gijn J. Incidence of subarachnoid hemorrhage: Role of region, year, and rate of computed tomography: A meta-analysis. Stroke 1996;27(4):625-9.
40. Lo EH. A new penumbra: Transitioning from injury into repair after stroke. Nat Med. 2008;14(5):497-500.
41. Lu H, Shi JX, Chen HL, Hang CH, Wang HD, Yin HX. Expression of monocyte chemoattractant protein-1 inthe cerebral artery after experimental subarachnoid hemmorrhage. Brain Res. 2009;1262: 73-80.
42. Matz PG, Copin JC, Chan PH. Cell death after exposure to subarachnoid hemolysate correlates inversely with expression of CuZn-superoxide dismutase. Stroke 2000;31:2450-59.
43. McGirtMJ, Blessing R, AlexanderMJ, Nimjee SM, Woodworth GF, Friedman AH, et al. Risk of cerebral vasospasm after subarachnoid hemorrhage reduced by statin therapy: A multivariate analysis of an institutional experience. J Neurosurg. 2006;105:671-74.
44. McGirt MJ, Lynch JR, Parra A, Sheng H, Pearlstein RD, Laskowitz DT, et al. Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage. Stroke 2002;33:2950-56.
45. McGirt MJ, Parra A, Sheng H, Higuchi Y, Oury TD, Laskowitz DT, et al. Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. Stroke 2002;33:2317-23.
46. McGirt MJ, Pradilla G, Legnani FG, Thai QA, Recinos PF, Tamargo RJ, et al. Systemic administration of simavastatin after the onset of experimental subarachnoid hemorrhage attenuates cerebral vasospasm. Neurosurgery 2006;58(5):945-51.
47. Mori T, Nagata K, Town T, Tan J, Matsui T, Asano T. Intracisternal increase of superoxide anion production in a canine subarachnoid hemorrhage model. Stroke 2001;32:636-42.
48. Nishihashi T, Trandafir CC,Wang A, Ji X, Shimizu Y, Kurahashi K. Hypersensitivity to hydroxyl radicals in rat basilar artery after subarachnoid hemorrhage. J Pharmacol Sci. 2006;100(3):234-6.
49. O'Driscoll G, Green D, Taylor RR. Simvastatin, an HMGcoenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997;95:1126-31.
50. Ohyama H, Hosomi N, Takahashi T, Mizushige K, Kohno M. Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia. Brain Res. 2001;902(2):264-71.
51. Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005;25:554-71.
52. Osuka K, Watanabe Y, Usuda N, Atsuzawa K, Yoshida J, Takayasu M. Modification of endothelial nitric oxide synthase through AMPK after experimental subarachnoid hemorrhage. J Neurotrauma. 2009;26(7):1157-65.
53. Pluta RM. Delayed cerebral vasospasm and nitric oxide: Review, new hypothesis, and proposed treatment. Pharmacol Ther. 2005;105(1):23-56.
54. Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: Role of the HIF system. Nat Med. 2003;9:677-84.
55. Rubanyi GM, Polokoff MA. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev. 1994;46:325-415.
56. Santhanam AV, Smith LA, Akiyama M, Rosales AG, Bailey KR, Katusic ZS. Role of endothelial NO synthase phosphorylation in cerebrovascular protective effect of recombinant erythropoietin during subarachnoid hemorrhage-induced cerebral vasospasm. Stroke 2005;36(12):2731-7.
57. Schievink WI. Intracranial aneurysms. N Engl J Med. 1997;336: 28-40.
58. Schubert GA, Schilling L, Thome C. Clazosentan, an endothelin receptor antagonist, prevents early hypoperfusion during the acute phase of massive experimental subarachnoid hemorrhage: A laser doppler flowmetry study in rats. J Neurosurg. 2008;109(6):1134-40.
59. Semenza GL. Signal transduction to hypoxia inducible factor 1. Biochem Pharmacol. 2002;64:993-8.
60. Sen O, Caner H, Aydin MV, Ozem O, Atalay B, Altinors N, et al. The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. Neurol Res. 2006;28:859-63.
61. Shih HC, Lin CL, Lee TY, Lee WS, Hsu C. 17beta-estradiol inhibits subarachnoid hemorrhage-induced inducible nitric oxide synthase gene expression by interfering with the nuclear factor kappa B transsaction. Stroke 2006;37(12):3025-31.
62. Shih HC, Lin CL, Wu SC, Kwan AL, Hong YR, Howng SL. Upregulation of estrogen receptor alpha and mediation of 17betaestradiol vasoprotective effects via estrogen receptor alpha in basilar arteries in rats after experimental subarachnoid hemorrhage. J Neurosurg. 2008;109(1):92-9.
63. Sugawara T, Ayer R, Jadhav V, Chen W, Tsubokawa T, Zhang JH. Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase. J Neurosci Res. 2008;86(16):3635-43.
64. Sugawara T, Jadhav V, Ayer R, Chen W, Suzuki H, Zhang JH. Thrombin inhibition by argatroban ameliorate early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. Stroke 2009;40:1530-32.
65. Tsurutani H, Ohkuma H, Suzuki S. Effects of thrombin inhibitor on thrombin-related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. Stroke 2003;34(6): 1497-500.
66. Vatter H, Weidauer S, Dias S, Preibisch C, Ngone S, Raabe A, et al. Persistence of the nitric oxide-dependent vasodilator pathway of cerebral vessels after experimental subarachnoid hemorrhage. Neurosurgery 2007;60(1):179-87.
67. Vatter H, Konczalla J, Weidauer S, Preibisch C, Raabe A, Zimmermann M, et al. Characterization of the endothelin-B receptor expression and vasomotor function during experimental cerebral vasospasm. Neurosurgery 2007;60(6):1100-8.
68. Voldby B, Enevoldsen EM. Intracranial pressure changes following aneurysm rupture. Part 1: Clinical and angiographic correlations. J Neurosurg. 1982;56:186-96.
69. Wardlaw JM, White PM. The detection and management of unruptured intracranial aneurysms. Brain 2000;123:205-21.
70. Wilkins RH. Cerebral vasospasm. Crit RevNeurobiol. 1990;6:51-77.
71. Yamaji T, Johshita H, Ishibashi M. Endothelin family in human plasma and cerebrospinal fluid. J Clin Endocrinol Metab. 1990;71:1611-15.
72. Yan J, Chen C, Lei J, Yang L, Wang K, Liu J, et al. 2-methoxyestradiol reduces cerebral vasospasm after 48 hours of experimental subarachnoid hemorrhage in rats. Exp Neurol. 2006;202 (2):348-56.
73. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. Novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332(6163):411-5.
74. Zhou C, Yamaguchi M, Kusaka G, Schonholz C, Nanda A, Zhang JH. Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2004;24:419-31.
75. Zhou ML, Shi JX, Hang CH, Cheng HL, Qi XP, Mao L, et al. Potential contribution of nuclear factor-kappaB to cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits. J Cereb Blood Flow Metab. 2007;27(9):1583-92.
76. Zimmermann M, Seifer V. Endothelin and subarachnoid hemorrhage: An overview. Neurosurgery 1998;43(4):863-75.