Molecular keys to the problems of cerebral vasospasm

Neurosurgery

Volumn 46, Issue 3, 2000, Pages 517-530

  Dietrich, Hans H ^a   Dacey Jr , Ralph G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral macrocirculation; Cerebral microcirculation; Cerebrovascular regulation; Molecular mechanisms; Subarachnoid hemorrhage

Indexed keywords

ENDOTHELIUM DERIVED CONSTRICTING FACTOR; ENDOTHELIUM DERIVED RELAXING FACTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ARTICLE; AUTOREGULATION; BLOOD COMPONENT; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; CEREBROSPINAL FLUID; ENDOTHELIUM CELL; GENE ACTIVATION; GENE THERAPY; IMMEDIATE EARLY GENE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE TONE; SUBARACHNOID HEMORRHAGE; VASCULAR SMOOTH MUSCLE; VASOSPASM;

EID: 0034021806     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-200003000-00001     Document Type: Article

References (160)

1. Akopov S, Sercombe R, Seylaz J: Cerebrovascular reactivity: Role of endothelium/platelet/leukocyte interactions. Cerebrovasc Brain Metab Rev 8:11-94, 1996.
2. Alabadi JA, Torregrosa G, Miranda FJ, Salom JB, Centeno JM, Alborch E: Impairment of the modulatory role of nitric oxide on the endothelin-1-elicited contraction of cerebral arteries: A pathogenetic factor in cerebral vasospasm after subarachnoid hemorrhage? Neurosurgery 41:245-253, 1997.
3. Ames A III, Wright RL, Kowada M, Thurston JM, Majno G: Cerebral ischemia: Part II - The no-reflow phenomenon. Am J Pathol 52:437-453, 1968.
4. Aoki T, Takenaka K, Suzuki S, Kassell NF, Sagher O, Lee KS: The role of hemolysate in the facilitation of oxyhemoglobin-induced contraction in rabbit basilar arteries. J Neurosurg 81:261-266, 1994.
5. Armstead WM, Leffler CW: Neurohumoral regulation of the cerebral circulation. Proc Soc Exp Biol Med 199:149-157, 1992.
6. Asano T, Sano K: Pathogenetic role of no-reflow phenomenon in experimental subarachnoid hemorrhage in dogs. J Neurosurg 46:454-466, 1977.
7. Bayliss WM: On the local reactions of the arterial wall to changes in internal pressure. J Physiol (Lond) 28:220-231, 1902.
8. Bederson JB, Levy AL, Ding WH, Kahn R, DiPerna CA, Jenkins AL III, Vallabhajosyula P: Acute vasoconstriction after subarachnoid hemorrhage. Neurosurgery 42:352-360, 1998.
9. Bevan JA: Sites of transition between functional systemic and cerebral arteries of rabbits occur at embryological junctional sites. Science 204:635-637, 1979.
10. Bodin P, Burnstock G: ATP-stimulated release of ATP by human endothelial cells. J Cardiovasc Pharmacol 27:872-875, 1996.
11. Bolton TB, Lang RJ, Takewaki T: Mechanisms of action of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery. J Physiol (Lond) 351:549-572, 1984.
12. Broderick JP, Brott TG, Duldner JE, Tomsick T, Leach A: Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 25:1342-1347, 1994.
13. Burnstock G: Local control of blood pressure by purines. Blood Vessels 24:156-160, 1987.
14. Busch E, Beaulieu C, de Crespigny A, Moseley ME: Diffusion MR imaging during acute subarachnoid hemorrhage in rats. Stroke 29:2155-2161, 1998.
15. Butler WE, Peterson JW, Zervas NT, Morgan KG: Intracellular calcium, myosin light chain phosphorylation, and contractile force in experimental cerebral vasospasm. Neurosurgery 38:781-788, 1996.
16. Chen G, Suzuki H, Weston AH: Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol 95:1165-1174, 1988.
17. Clozel M, Watanabe H: BQ-123, a peptidic endothelin ETa receptor antagonist, prevents the early cerebral vasospasm following subarachnoid hemorrhage after intracisternal but not intravenous injection. Life Sci 52:825-834, 1992.
18. i. Am J Physiol 262:H754-H762, 1992.
19. Cook DA: Mechanisms of cerebral vasospasm in subarachnoid haemorrhage. Pharmacol Ther 66:259-284, 1995.
20. Corr L, Burnstock G: Analysis of P2-purinoceptor subtypes on the smooth muscle and endothelium of rabbit coronary artery. J Cardiovasc Pharmacol 23:709-715, 1994.
21. Cosentino F, Katusic ZS: Does endothelin-1 play a role in the pathogenesis of cerebral vasospasm? Stroke 25:904-908, 1994.
22. Cox SB, Woolsey TA, Rovainen CM: Localized dynamic changes in cortical blood flow with whisker stimulation corresponds to matched vascular and neuronal architecture of rat barrels. J Cereb Blood Flow Metab 13:899-913, 1993.
23. Dacey RG Jr, Duling BR: A study of rat intracerebral arterioles: Methods, morphology, and reactivity. Am J Physiol 243:H598-H606, 1982.
24. Dacey RG Jr, Duling BR: Effect of norepinephrine on penetrating arterioles of rat cerebral cortex. Am J Physiol 246:H380-H385, 1984.
25. Davies PF, Barbee KA, Volin MV, Robotewskyj A, Chen J, Joseph L, Griem ML, Wernick MN, Jacobs E, Polacek DC, DePaola N, Barakat AI: Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annu Rev Physiol 59:527-549, 1997.
26. del Zoppo GJ: Microvascular changes during cerebral ischemia and reperfusion. Cerebrovasc Brain Metab Rev 6:47-96, 1994.
27. Dietrich HH, Kajita Y, Dacey RG Jr: Local and conducted vasomotor responses in isolated rat cerebral arterioles. Am J Physiol 271:H1109-H1116, 1996.
28. Dietrich HH, Kimura M, Dacey RG Jr: N-omega-L-arginine constricts cerebral arterioles without increasing intracellular calcium levels. Am J Physiol 266:H1681-H1686, 1994.
29. Doi M, Kasuya H, Weir B, Cook DA, Ogawa A: Reduced expression of calponin in canine basilar artery after subarachnoid haemorrhage. Acta Neurochir (Wien) 139:77-81, 1997.
30. Dreier JP, Korner K, Ebert N, Gorner A, Rubin I, Back T, Lindauer U, Wolf T, Villringer A, Einhaupl KM, Lauritzen M, Dirnagl U: Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space. J Cereb Blood Flow Metab 18:978-990, 1998.
31. Duling BR, Berne RM: Propagated vasodilation in the microcirculation of the hamster cheek pouch. Circ Res 26:163-170, 1970.
32. Ecker A, Riemenschneider PA: Arteriographic demonstration of spasm of the intracranial arteries. J Neurosurg 8:660-667, 1951.
33. Edwards DH, Byrne JV, Griffith TM: The effect of chronic subarachnoid hemorrhage on basal endothelium-derived relaxing factor activity in intrathecal cerebral arteries. J Neurosurg 76: 830-837, 1992.
34. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396:269-272, 1998.
35. Eichstaedt E, Cordes M, Reyes R, Danne O: Quantification of regional blood flow with HMPAO-SPECT after subarachnoid bleeding and vasospasm. Can J Neurol Sci 20[Suppl 1]:S6, 1993 (abstr).
36. Fadel MM, Foley PL, Kassell NF, Lee KS: Histidine attenuates cerebral vasospasm in a rabbit model of subarachnoid hemorrhage. Surg Neurol 43:52-58, 1995.
37. Faraci FM: Role of nitric oxide in regulation of basilar artery tone in vivo. Am J Physiol 259:H1216-H1221, 1990.
38. Faraci FM, Brian JE Jr: Nitric oxide and the cerebral circulation. Stroke 25:692-703, 1994.
39. Faraci FM, Heistad DD: Regulation of the cerebral circulation: Role of endothelium and potassium channels. Physiol Rev 78: 53-97, 1998.
40. Faraci FM, Sobey CG: Role of potassium channels in regulation of cerebral vascular tone. J Cereb Blood Flow Metab 18:1047-1063, 1998.
41. Feigin VL, Rinkel GJ, Algra A, Vermeulen M, van Gijn J: Calcium antagonists in patients with aneurysmal subarachnoid hemorrhage: A systematic review. Neurology 50:876-883, 1998.
42. Fleisch A: Les réflexes nutritifs ascendant producteurs de dilation artérielle. Arch Int Physiol 41:141-167, 1935.
43. Fleming I, Bauersachs J, Busse R: Paracrine functions of the coronary vascular endothelium. Mol Cell Biochem 157:137-145, 1996.
44. Fox JL: Intracranial vasospasm: A study with iron compounds. Surg Neurol 11:363-368, 1979.
45. Gaetani P, Cafe C, Rodriguez Y, Baena R, Tancioni F, Torri C, Tartara F, Marzatico F: Superoxide dismutase activity in asternal cerebrospinal fluid after aneurysmal subarachnoid haemorrhage. Acta Neurochir (Wien) 139:1033-1037, 1997.
46. Garcia-Roldan JL, Bevan JA: Flow-induced constriction and dilation of cerebral resistance arteries. Circ Res 66:1445-1448, 1990.
47. Géraud G, Tremoulet M, Guell A, Bes A: The prognostic value of noninvasive CBF measurement in subarachnoid hemorrhage. Stroke 15:301-305, 1984.
48. Gibson QH, Roughton FJW: The kinetics and equilibria of the reactions of nitric oxide with sheep haemoglobin. J Physiol (Lond) 136:507-526, 1957.
49. Golding EM, Robertson CS, Bryan RM Jr: Comparison of the myogenic response in rat cerebral arteries of different calibers. Brain Res 785:293-298, 1998.
50. Haley EC Jr, Kassell NF, Alves WM, Weir BK, Hansen CA: Phase II trial of tirilazad in aneurysmal subarachnoid hemorrhage: A report of the Cooperative Aneurysm Study. J Neurosurg 82:786-790, 1995.
51. Harder DR, Dernbach P, Waters A: Possible cellular mechanism for cerebral vasospasm after experimental subarachnoid hemorrhage in the dog. J Clin Invest 80:875-880, 1987.
52. Heistad DD, Kontos HA: Cerebral circulation, in Shepherd JT, Abboud FM (eds): Handbook of Physiology. Section 2: Circulation. Bethesda, American Physiological Society, 1983, vol 3, pp 137-182.
53. Herrera DG, Robertson HA: Activation of c-fos in the brain. Prog Neurobiol 50:83-107, 1996.
54. Herz DA, Baez S, Shulman K: Pial microcirculation in subarachnoid hemorrhage. Stroke 6:417-424, 1975.
55. Hino A, Tokuyama Y, Kobayashi M, Yano M, Weir B, Takeda J, Wang X, Bell GI, Macdonald RL: Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys. J Cereb Blood Flow Metab 16:688-697, 1996.
56. Hino A, Tokuyama Y, Weir B, Takeda J, Yano H, Bell GI, Macdonald RL: Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. Neurosurgery 39:562-568, 1996.
57. Hongo K, Ogawa H, Kassell NF, Nakagomi T, Saski T, Tsukahara T, Lehman RM: Comparison of intraluminal and extraluminal inhibitory effects of hemoglobin on endothelium-dependent relaxation of rabbit basilar artery. Stroke 19:1550-1555, 1988.
58. Ignarro LJ: Biosynthesis and metabolism of endothelium-derived nitric oxide. Annu Rev Pharmacol Toxicol 30:535-560, 1990.
59. Ignarro LJ, Byrns RE, Buga GM, Wood KS: Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ Res 61:866-879, 1987.
60. Ingall TJ, Whisnant JP: Epidemiology of subarachnoid hemorrhage, in Yanagihara T, Piepgras DG, Atkinson JLD (eds): Subarachnoid Hemorrhage. New York, Marcel Dekker, Inc., 1998, pp 63-78.
61. Inoue K, Koizumi S, Ueno S: Implication of ATP receptors in brain functions. Prog Neurobiol 50:483-485, 1996.
62. Inscho EW, Mitchell KD, Navar LG: Extracellular ATP in the regulation of renal microvascular function. FASEB J 8:319-328, 1994.
63. Janigro D, Nguyen TS, Meno J, West GA, Winn HR: Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP. Am J Physiol 273:H878-H885, 1997.
64. Kajita Y, Dietrich HH, Dacey RG Jr: Effects of oxyhemoglobin on local and propagated vasodilatory responses induced by adenosine, adenosine diphosphate, and adenosine triphosphate in rat cerebral arterioles. J Neurosurg 85:908-916, 1996.
65. Kasuya H, Weir BK, Nakane M, Pollock JS, Johns L, Marton LS, Stefansson K: Nitric oxide synthase and guanylate cyclase levels in canine basilar artery after subarachnoid hemorrhage. J Neurosurg 82:250-255, 1995.
66. Katusic ZS, Shepherd JT: Endothelium-derived vasoactive factors: Part II - Endothelium-dependent contraction. Hypertension 18:III86-III92, 1991.
67. Kawamata T, Peterson JW, Bun T, Zervas NT: Augmentation of both hemolysate-induced contraction and activation of protein kinase C by submaximum activation in canine cerebral arteries in vitro. J Neurosurg 87:908-915, 1997.
68. Kawamura S, Sayama I, Yasui N, Uemura K: Sequential changes in cerebral blood flow and metabolism in patients with subarachnoid haemorrhage. Acta Neurochir (Wien) 114:12-15, 1992.
69. Kim P: Animal models of subarachnoid hemorrhage and vasospasm, in Yanagihara T, Piepgras DG, Atkinson JLD (eds): Subarachnoid Hemorrhage. New York, Marcel Dekker, Inc., 1998, pp 11-27.
70. Kim P: Pharmacological modification of experimental vasospasm, in Yanagihara T, Piepgras DG, Atkinson JLD (eds): Subarachnoid Hemorrhage. New York, Marcel Dekker, Inc., 1998, pp 29-61.
71. Kim P, Lorenz RR, Sundt TM Jr, Vanhoutte PM: Release of endothelium-derived relaxing factor after subarachnoid hemorrhage. J Neurosurg 70:108-114, 1989.
72. Kim P, Schini VB, Sundt TM Jr, Vanhoutte PM: Reduced production of cGMP underlies the loss of endothelium-dependent relaxations in the canine basilar artery after subarachnoid hemorrhage. Circ Res 70:248-256, 1992.
73. 2+ channels in rat basilar smooth muscle cells. J Vasc Res 33:258-264, 1996.
74. Kitazono T, Faraci FM, Taguchi H, Heistad DD: Role of potassium channels in cerebral blood vessels. Stroke 26:1713-1723, 1995.
75. B receptor and nitric oxide in cats. Neurosci Lett 176:157-160, 1994.
76. Kurjiaka DT, Segal SS: Conducted vasodilation elevates flow in arteriole networks of hamster striated muscle. Am J Physiol 269:H1723-H1728, 1995.
77. Kuroki M, Kanamaru K, Suzuki H, Waga S, Semba R: Effect of vasospasm on heme oxygenases in a rat model of subarachnoid hemorrhage. Stroke 29:683-689, 1998.
78. Kwan AL, Lin CL, Yanamoto H, Howng SL, Kassell NF, Lee KS: Systemic administration of the potassium channel activator cromakalim attenuates cerebral vasospasm after experimental subarachnoid hemorrhage. Neurosurgery 42:347-351, 1998.
79. Kwan AL, Solenski NJ, Kassell NF, Lee KS: Inhibition of nitric oxide generation and lipid peroxidation attenuates hemolysate-induced injury to cerebrovascular endothelium. Acta Neurochir (Wien) 139:240-248, 1997.
80. Lonnberg H, Vuorio E: Towards genomic drug therapy with antisense oligonucleotides. Ann Med 28:511-522, 1996.
81. Macdonald RL, Zhang J, Weir B, Marton LS, Wollman R: Adenosine triphosphate causes vasospasm of the rat femoral artery. Neurosurgery 42:825-833, 1998.
82. MacManus JP, Linnik MD: Gene expression induced by cerebral ischemia: An apoptotic perspective. J Cereb Blood Flow Metab 17:815-832, 1997.
83. Marshman LA, Morice AH, Thompson JS: Increased efficacy of sodium nitroprusside in middle cerebral arteries following acute subarachnoid hemorrhage: Indications for its use after rupture. J Neurosurg Anesthesiol 10:171-177, 1998.
84. Martin W, Villani GM, Jothianandan D, Furchgott RF: Blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation of rabbit aorta by certain ferrous hemoproteins. J Pharmacol Exp Ther 233:679-685, 1985.
85. Martin W, Villani GM, Jothianandan D, Furchgott RF: Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J Pharmacol Exp Ther 232:708-716, 1985.
86. 2+i elevation induced by hemolysate in bovine endothelial cells: Implications for cerebral vasospasm. Neurol Res 18:349-353, 1996.
87. Massa SM, Swanson RA, Sharp FR: The stress gene response in brain. Cerebrovasc Brain Metab Rev 8:95-158, 1996.
88. Mathew NT, Meyer JS, Hartmann A: Diagnosis and treatment of factors complicating subarachnoid hemorrhage. Neuroradiology 6:237-245, 1974.
89. Matz PG, Massa SM, Weinstein PR, Turner C, Panter SS, Sharp FR: Focal hyperexpression of hemeoxygenase-1 protein and messenger RNA in rat brain caused by cellular stress following subarachnoid injections of lysed blood. J Neurosurg 85:892-900, 1996.
90. Matz PG, Sundaresan S, Sharp FR, Weinstein PR: Induction of HSP70 in rat brain following subarachnoid hemorrhage produced by endovascular perforation. J Neurosurg 85:138-145, 1996.
91. Matz P, Turner C, Weinstein PR, Massa SM, Panter SS, Sharp FR: Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage. Brain Res 713: 211-222, 1996.
92. Matz P, Weinstein P, States B, Honkaniemi J, Sharp FR: Subarachnoid injections of lysed blood induce the hsp70 stress gene and produce DNA fragmentation in focal areas of the rat brain. Stroke 27:504-513, 1996.
93. Meixensberger J: Xenon 133: CBF measurements in severe head injury and subarachnoid haemorrhage. Acta Neurochir Suppl (Wien) 59:28-33, 1993.
94. Misra HP, Fridovich I: The generation of superoxide radical during the autoxidation of hemoglobin. J Biol Chem 247:6960-6962, 1972.
95. Mombouli JV, Vanhoutte PM: Kinins and endothelial control of vascular smooth muscle. Annu Rev Pharmacol Toxicol 35:679-705, 1995.
96. Morreale VM, Meissner I: Intracranial aneurysms, in Yanagihara T, Piepgras DG, Atkinson JLD (eds): Subarachnoid Hemorrhage. New York, Marcel Dekker, Inc., 1998, pp 79-112.
97. Muramatsu I: Purinergic transmission in cerebral arteries, in Phillis JW (ed): The Regulation of Cerebral Blood Flow. Boca Raton, CRC Press, 1993, pp 225-231.
98. Muramatsu I, Kigoshi S: Purinergic and non-purinergic innervation in the cerebral arteries of the dog. Br J Pharmacol 92:901-908, 1987.
99. Muramatsu I, Ohmura T, Oshita M: Comparison between sympathetic adrenergic and purinergic transmission in the dog mesenteric artery. J Physiol (Lond) 411:227-243, 1989.
100. Myers PR, Guerra R Jr, Harrison DG: Release of NO and EDRF from cultured bovine endothelial cells. Am J Physiol 256:H1030-H1037, 1989.
101. Nagai H, Katsumata T, Ohya M, Kageyama N: Effect of subarachnoid haemorrhage on micro-circulation in hypothalamus and brain stem of dogs. Neurochirurgia (Stuttg) 19:135-144, 1976.
102. Nagai H, Suzuki Y, Sugiura M, Noda S, Mabe H: Experimental cerebral vasospasm: Part I - Factors contributing to early spasm. J Neurosurg 41:285-292, 1974.
103. Nakashima S, Tabuchi K, Shimokawa S, Fukuyama K, Mineta T, Abe M: Combination therapy of fasudil hydrochloride and ozagrel sodium for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Neurol Med Chir (Tokyo) 38:805-811, 1998.
104. Nakashima T, Takenaka K, Fukazawa S, Ando T, Sakai N, Yamada H, Banno Y, Nozawa Y: Purification of a factor from CSF in patient after SAH which induces the cytosolic free calcium elevation in vascular smooth muscle cells. Neurol Res 19:51-56, 1997.
105. Nakashima T, Takenaka K, Fukazawa S, Yano K, Nishimura Y, Andoh T, Sakai N, Yamada H: Cytosolic free calcium elevation in vascular smooth muscle cells induced by cerebrospinal fluid from patients with subarachnoid hemorrhage: Biochemical nature of the calcium-mobilizing factor. Neurol Med Chir (Tokyo) 35:8-12, 1995.
106. Ngai AC, Winn HR: Modulation of cerebral arteriolar diameter by intraluminal flow and pressure. Circ Res 77:832-840, 1995.
107. Nishizawa S, Yamamoto S, Yokoyama T, Uemura K: Dysfunction of nitric oxide induces protein kinase C activation resulting in vasospasm after subarachnoid hemorrhage. Neurol Res 19: 558-562, 1997.
108. Ohkuma H, Itoh K, Shibata S, Suzuki S: Morphological changes of intraparenchymal arterioles after experimental subarachnoid hemorrhage in dogs. Neurosurgery 41:230-236, 1997.
109. Oka Y, Ohta S, Todo H, Kohno K, Kumon Y, Sakaki S: Protein synthesis and immunoreactivities of contraction-related proteins in smooth muscle cells of canine basilar artery after experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab 16:1335-1344, 1996.
110. Ono S, Date I, Nakajima M, Onoda K, Ogihara K, Shiota T, Asari S, Ninomiya Y, Yabuno N, Ohmoto T: Three-dimensional analysis of vasospastic major cerebral arteries in rats with the corrosion cast technique. Stroke 28:1631-1638, 1997.
111. Onoda K, Ono S, Ogihara K, Shiota T, Asari S, Ohmoto T, Ninomiya Y: Inhibition of vascular contraction by intracisternal administration of preproendothelin-1 mRNA antisense oligoDNA in a rat experimental vasospasm model. J Neurosurg 85:846-852, 1996.
112. Onoue H, Katusic ZS: Subarachnoid hemorrhage and the role of potassium channels in relaxations of canine basilar artery to nitrovasodilators. J Cereb Blood Flow Metab 18:186-195, 1998.
113. Onoue H, Katusic ZS: The effect of subarachnoid hemorrhage on mechanisms of vasodilation mediated by cyclic adenosine monophosphate. J Neurosurg 89:111-117, 1998.
114. Onoue H, Kaito N, Akiyama M, Tomii M, Tokudome S, Abe T: Altered reactivity of human cerebral arteries after subarachnoid hemorrhage. J Neurosurg 83:510-515, 1995.
115. Onoue H, Tsutsui M, Smith L, Stelter A, O'Brien T, Katusic ZS: Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage. Stroke 29:1959-1966, 1998.
116. Palmer RM, Ferrige AG, Moncada S: Nitric oxide accounts for the biological activity of endothelium-dependent relaxing factor. Nature 327:524-526, 1987.
117. Parsaee H, McEwan JR, Joseph S, MacDermot J: Differential sensitivities of the prostacyclin and nitric oxide biosynthetic pathways to cytosolic calcium in bovine aortic endothelial cells. Br J Pharmacol 107:1013-1019, 1992.
118. + channels in cerebral vasodilatation induced by increases in cyclic GMP and cyclic AMP in the rat. Stroke 27:1603-1607, 1996.
119. Piepgras A, Thome C, Schmiedek P: Characterization of an anterior circulation rat subarachnoid hemorrhage model. Stroke 26:2347-2352, 1995.
120. Plane F, Garland CJ: Electrophysiology of cerebral blood vessels. Pharmacol Ther 56:341-358, 1992.
121. Pluta RM, Afshar JK, Boock RJ, Oldfield EH: Temporal changes in perivascular concentrations of oxyhemoglobin, deoxyhemoglobin, and methemoglobin after subarachnoid hemorrhage. J Neurosurg 88:557-561, 1998.
122. Pluta RM, Boock RJ, Afshar JK, Clouse K, Bacic M, Ehrenreich H, Oldfield EH: Source and cause of endothelin-1 release into cerebrospinal fluid after subarachnoid hemorrhage. J Neurosurg 87:287-293, 1997.
123. 2+ sensitivity. Can J Physiol Pharmacol 72:1420-1426, 1994.
124. Rosenblum WI, Weinbrecht P, Nelson GH: Propagated constriction in mouse pial arterioles: Possible role of endothelium in transmitting the propagated response. Microcirc Endothelium Lymphatics 6:369-387, 1990.
125. Rowland RT, Cleveland JC Jr, Meng X, Harken AH, Brown JM: Potential gene therapy strategies in the treatment of cardiovascular disease. Ann Thorac Surg 60:721-728, 1995.
126. Rubanyi GM, Polokoff MA: Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 46:325-415, 1994.
127. Rubanyi GM, Vanhoutte PM: Nature of endothelium-derived relaxing factor: Are there two relaxing mediators? Circ Res 61:II61-II67, 1987.
128. 2+ concentration. Eur J Biochem 250:689-697, 1997.
129. Samdani AF, Dawson TM, Dawson VL: Nitric oxide synthase in models of focal ischemia. Stroke 28:1283-1288, 1997.
130. Sato A, Sato Y: Regulation of regional cerebral blood flow by cholinergic fibers originating in the basal forebrain. Neurosci Res 14:242-274, 1992.
131. Sayama T, Suzuki S, Fukui M: Expression of inducible nitric-oxide synthase in rats following subarachnoid hemorrhage. Neurol Res 20:79-84, 1998.
132. Schiffrin EL, Touyz RM: Vascular biology of endothelin. J Cardiovasc Pharmacol 32[Suppl 3]:S2-S13, 1998.
133. Schilling L, Parsons AA, Wahl M: Effects of potassium channel activators on isolated cerebral arteries of large and small diameter in the cat. J Neurosurg 83:123-128, 1995.
134. Schubert R, Serebryakov VN, Mewes H, Hopp HH: Iloprost dilates rat small arteries: Role of KATP- and KCa-channel activation by cAMP-dependent protein kinase. Am J Physiol 272: H1147-H1156, 1997.
135. 2-purinoceptor antagonists on hemolysate-induced and adenosine 5′-triphosphate-induced contractions of dog basilar artery in vitro. Neurosurgery 39:815-822, 1996.
136. + channels in chronically hypertensive rats. Stroke 28:392-397, 1997.
137. Sonobe M, Suzuki J: Vasospasmogenic substances produced following subarachnoid haemorrhage, and its fate. Acta Neurochir (Wien) 44:97-106, 1978.
138. Steele JA, Stockbridge N, Maljkovic G, Weir B: Free radicals mediate actions of oxyhemoglobin on cerebrovascular smooth muscle cells. Circ Res 68:416-423, 1991.
139. Sun H, Kanamaru K, Ito M, Suzuki H, Kojima T, Waga S, Kureishi Y, Nakano T: Myosin light chain phosphorylation and contractile proteins in a canine two-hemorrhage model of subarachnoid hemorrhage. Stroke 29:2149-2154, 1998.
140. Symon L: The concept of intracerebral steal. Int Anesthesiol Clin 7:597-615, 1969.
141. Takayasu M, Kajita Y, Suzuki Y, Mori Y, Shibuya M, Sugita K, Hidaka H: Oxyhemoglobin enhancement of vasopressin-induced constriction in rat cerebral arterioles. Life Sci 56:PL123-PL127, 1995.
142. Tanaka Y, Kassell NF, Machi T, Toshima M, Dougherty DA: Effect of bilirubin on rabbit cerebral arteries in vivo and in vitro. Neurosurgery 30:195-201, 1992.
143. Tanazawa T, Suzuki Y, Anzai M, Tsugane S, Takayasu M, Shibuya M: Vasodilation by intrathecal lipopolysaccharide of the cerebral arteries after subarachnoid haemorrhage in dogs. Acta Neurochir (Wien) 138:330-337, 1996.
144. Todo H, Ohta S, Wang J, Ichikawa H, Ohue S, Kumon Y, Sakaki S: Impairment in biochemical level of arterial dilative capability of a cyclic nucleotides-dependent pathway by induced vasospasm in the canine basilar artery. J Cereb Blood Flow Metab 18:808-817, 1998.
145. Tomasello F, Albanese V, Picozzi P, Spadaro A, Conforti P: Relation of cerebral vasospasm to operative findings of subarachnoid blood around ruptured aneurysms. Acta Neurochir (Wien) 60:55-62, 1982.
146. Toshima Y, Satoh S, Ikegaki I, Asano T, Suzuki Y, Shibuya M: Thromboxane A2 synthetase inhibitor failed to ameliorate the arterial narrowing during the chronic phase of cerebral vasospasm. Life Sci 61:1371-1377, 1997.
147. 99mTc-HMPAO tomography. Eur J Nucl Med 20:53-58, 1993.
148. Vermeulen M: Subarachnoid haemorrhage: Diagnosis and treatment. J Neurol 243:496-501, 1996.
149. Vollrath B, Chan P, Findlay M, Cook D: Lazaroids and deferoxamine attenuate the intracellular effects of oxyhaemoglobin in vascular smooth muscle. Cardiovasc Res 30:619-626, 1995.
150. Watkins MT, Haudenschild CC, Al-Badawi H, Velazquez FR, Larson DM: Immediate responses of endothelial cells to hypoxia and reoxygenation: An in vitro model of cellular dysfunction. Am J Physiol 268:H749-H758, 1995.
151. Weir B: Subarachnoid Hemorrhage: Causes and Cures. New York, Oxford University Press, 1948.
152. Wilcox JN, Subramanian RR, Sundell CL, Tracer WR, Pollock JS, Harrison DG, Marsden PA: Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol 17:2479-2488, 1997.
153. Winder SJ, Allen BG, Clément-Chomienne O, Walsh MP: Regulation of smooth muscle actin-myosin interaction and force by calponin. Acta Physiol Scand 164:415-426, 1998.
154. Xu J, Qu ZX, Moore SA, Hsu CY, Hogan EL: Receptor-linked hydrolysis of phosphoinositides and production of prostacyclin in cerebral endothelial cells. J Neurochem 58:1930-1935, 1992.
155. Yamamoto S, Nishizawa S, Tsukada H, Kakiuchi T, Yokoyama T, Ryu H, Uemura K: Cerebral blood flow autoregulation following subarachnoid hemorrhage in rats: Chronic vasospasms shifts the upper and lower limits of the autoregulatory range toward higher blood pressures. Brain Res 782:194-201, 1998.
156. Yundt KD, Grubb RL Jr, Diringer MN, Powers WJ: Autoregulatory vasodilation of parenchymal vessels is impaired during cerebral vasospasm. J Cereb Blood Flow Metab 18:419-424, 1998.
157. Zhang H, Weir BK, Macdonald RL, Marton LS, Solenski NJ, Kwan AL, Lee KS: Mechanisms of [Ca++]i elevation induced by erythrocyte components in endothelial cells. J Pharmacol Exp Ther 277:1501-1509, 1996.
158. 2+]i elevation in cerebral smooth muscle cells. Am J Physiol 269:H1874-H1890, 1995.
159. Zuccarello M, Boccaletti R, Romano A, Rapoport RM: Endothelin B receptor antagonists attenuate subarachnoid hemorrhage-induced cerebral vasospasm. Stroke 29:1924-1929, 1998.
160. Zuccarello M, Bonasso CL, Lewis AI, Sperelakis N, Rapoport RM: Relaxation of subarachnoid hemorrhage-induced spasm of rabbit basilar artery by the K+ channel activator cromakalim. Stroke 27:311-316, 1996.