A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

Nature

Volumn 560, Issue 7718, 2018, Pages 377-381

  Plasschaert, Lindsey W ^a   Žilionis, Rapolas ^b,c   Choo Wing, Rayman ^a   Savova, Virginia ^b,e   Knehr, Judith ^d   Roma, Guglielmo ^d   Klein, Allon M ^b   Jaffe, Aron B ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c VILNIUS UNIVERSITY   (Lithuania)

^d NOVARTIS PHARMA AG   (Switzerland)

^e The Inflammation Research Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXI1 PROTEIN, HUMAN; FOXI1 PROTEIN, MOUSE; NOTCH RECEPTOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ADOLESCENT; ADULT; AIRWAY EPITHELIUM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL POPULATION; CELL REGENERATION; CFTR GENE; CHILD; CONTROLLED STUDY; CYSTIC FIBROSIS; ELECTROPHYSIOLOGY; FEMALE; GENE ACTIVITY; GENE MUTATION; HBEC CELL LINE (BRONCHIAL EPITHELIUM); HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; LETTER; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; NOTCH SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY IONOCYTE; SINGLE CELL ANALYSIS; TISSUE REPAIR; TONOPLAST; TRACHEA EPITHELIUM; ANIMAL; ANTIBODY SPECIFICITY; BRONCHUS; CELL CULTURE; CYTOLOGY; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PRESCHOOL CHILD; REGENERATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TRACHEA; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; BRONCHI; CELL DIFFERENTIATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMANS; MALE; MICE; ORGAN SPECIFICITY; RECEPTORS, NOTCH; REGENERATION; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; TRACHEA; VACUOLAR PROTON-TRANSLOCATING ATPASES; YOUNG ADULT;

EID: 85051647983     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-018-0394-6     Document Type: Article

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