Airway acidification initiates host defense abnormalities in cystic fibrosis mice

Science

Volumn 351, Issue 6272, 2016, Pages 503-507

  Shah, Viral S ^a   Meyerholz, David K ^a   Tang, Xiao Xiao ^a,b   Reznikov, Leah ^a   Alaiwa, Mahmoud Abou ^a   Ernst, Sarah E ^a,b   Karp, Philip H ^a,b   Wohlford Lenane, Christine L ^a   Heilmann, Kristopher P ^b   Leidinger, Mariah R ^a   Allen, Patrick D ^a   Zabner, Joseph ^a   McCray, Paul B ^a,b   Ostedgaard, Lynda S ^a   Stoltz, David A ^a,c   Randak, Christoph O ^a   Welsh, Michael J ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c University of Iowa   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ACID; ATP12A PROTEIN, HUMAN; BICARBONATE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE;

ABNORMALITY; ACIDIFICATION; ANION; BACTERIUM; BICARBONATE; DEFENSE MECHANISM; MUTATION; PIG; RODENT;

ACIDIFICATION; AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIUM; CONTROLLED STUDY; CYSTIC FIBROSIS; EXPERIMENTAL MODEL; HOST RESISTANCE; HUMAN; LIQUID; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; ANIMAL; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MOUSE; GENETICS; LUNG; METABOLISM; MICROBIOLOGY; PIG; TRANSGENIC MOUSE;

MUS; SUIDAE;

ACIDS; ANIMALS; BICARBONATES; CYSTIC FIBROSIS; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; HYDROGEN-ION CONCENTRATION; LUNG; MICE; MICE, INBRED CFTR; MICE, TRANSGENIC; SWINE;

EID: 84956707544     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad5589     Document Type: Article

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