Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung

Cell Reports

Volumn 10, Issue 2, 2015, Pages 239-252

  Danahay, Henry ^a,c   Pessotti, Angelica D ^a   Coote, Julie ^a   Montgomery, Brooke E ^a   Xia, Donghui ^a   Wilson, Aaron ^a   Yang, Haidi ^a   Wang, Zhao ^a   Bevan, Luke ^a   Thomas, Chris ^a   Petit, Stephanie ^a   London, Anne ^a   LeMotte, Peter ^a   Doelemeyer, Arno ^b   Vélez Reyes, Germán L ^a   Bernasconi, Paula ^a   Fryer, Christy J ^a   Edwards, Matt ^a   Capodieci, Paola ^a   Chen, Amy ^a   Hild, Marc ^a   Jaffe, Aron B ^a   more..

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; CYTOKINE; DNAIC2 PROTEIN; EPIDERMAL GROWTH FACTOR; FOXJ1 PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HOUSE DUST ALLERGEN; INTERLEUKIN 13; INTERLEUKIN 17; ITGA6 PROTEIN; MUCIN 5AC; MUCIN 5B; NEUTRALIZING ANTIBODY; NOTCH 2 RECEPTOR ANTIBODY; NOTCH2 RECEPTOR; TRP63 PROTEIN; UNCLASSIFIED DRUG; FOXA3 PROTEIN, HUMAN; MUC5AC PROTEIN, HUMAN; MUC5B PROTEIN, HUMAN; NOTCH2 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; CELL DIFFERENTIATION; CELL FATE; CHILD; CILIATED EPITHELIUM CELL; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GOBLE CELL METAPLASIA; GOBLET CELL; GOBLET CELL METAPLASIA; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METAPLASIA; MOUSE; MUCUS SECRETION; NONHUMAN; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENETICS; LUNG; METABOLISM; PATHOLOGY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; GOBLET CELLS; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; HUMANS; INTERLEUKIN-13; INTERLEUKIN-17; LUNG; METAPLASIA; MICE; MICE, INBRED BALB C; MUCIN 5AC; MUCIN-5B; RECEPTOR, NOTCH2; RECOMBINANT PROTEINS;

EID: 84920874540     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.12.017     Document Type: Article

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