Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

PLoS Pathogens

Volumn 14, Issue 6, 2018, Pages

  Rodríguez Pulido, Miguel ^a   Sánchez Aparicio, María Teresa ^b   Martínez Salas, Encarnación ^a   García Sastre, Adolfo ^b   Sobrino, Francisco ^a   Sáiz, Margarita ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INITIATION FACTOR 4G; LEADER PROTEASE; PROTEINASE; UNCLASSIFIED DRUG; DHX58 PROTEIN, HUMAN; LEADER PROTEINASE, FOOT-AND-MOUTH DISEASE VIRUS; RNA HELICASE;

ANTIVIRAL ACTIVITY; ARTICLE; BHK-21 CELL LINE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; FOOT AND MOUTH DISEASE VIRUS; GENE OVEREXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNOPRECIPITATION; INNATE IMMUNITY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SK-6 CELL LINE; ANIMAL; CELL CULTURE; CHLOROCEBUS AETHIOPS; ENZYMOLOGY; FOOT AND MOUTH DISEASE; GENETICS; HAMSTER; IMMUNOLOGY; METABOLISM; PATHOLOGY; VERO CELL LINE; VIROLOGY;

ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CRICETINAE; ENDOPEPTIDASES; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; HEK293 CELLS; HUMANS; IMMUNE EVASION; IMMUNITY, INNATE; RNA HELICASES; VERO CELLS;

EID: 85049363452     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1007135     Document Type: Article

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