The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinase

Journal of Virology

Volumn 85, Issue 8, 2011, Pages 3758-3766

  Wang, Dang ^a   Fang, Liurong ^a   Li, Ping ^a   Sun, Li ^b   Fan, Jinxiu ^a   Zhang, Qingye ^a   Luo, Rui ^a   Liu, Xiangtao ^c   Li, Kui ^d   Chen, Huanchun ^a   Chen, Zhongbin ^b   Xiao, Shaobo ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON; LEADER PROTEINASE; PHOSPHOTRANSFERASE; POLYUBIQUITIN; PROTEINASE; RETINOIC ACID INDUCIBLE PROTEIN I; TANK BINDING KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN SPECIFIC PROTEASE 14; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE RESPONSE; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME REGULATION; FOOT AND MOUTH DISEASE VIRUS; GENE MUTATION; GENETIC CONSERVATION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; KIDNEY CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; SARS CORONAVIRUS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SEROTYPE; SIGNAL TRANSDUCTION; STRUCTURAL BIOINFORMATICS; VIRUS CELL INTERACTION; VIRUS PATHOGENESIS;

AMINO ACID SEQUENCE; CELL LINE; CONSERVED SEQUENCE; ENDOPEPTIDASES; FOOT-AND-MOUTH DISEASE VIRUS; HUMANS; INTERFERON TYPE I; MODELS, MOLECULAR; UBIQUITIN; VIRAL PROTEINS;

FOOT-AND-MOUTH DISEASE VIRUS; SARS CORONAVIRUS;

EID: 79952837091     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02589-10     Document Type: Article

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