Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

Nature Biotechnology

Volumn 36, Issue 6, 2018, Pages 536-539

  Ryu, Seuk Min ^a,b   Koo, Taeyoung ^a   Kim, Kyoungmi ^a,c   Lim, Kayeong ^a,b   Baek, Gayoung ^a   Kim, Sang Tae ^a   Kim, Heon Seok ^a,b   Kim, Da Eun ^a,b   Lee, Hyunji ^a   Chung, Eugene ^a,b   Kim, Jin Soo ^a,b  

^a Institute for Basic Science   (South Korea)

^b Seoul National University   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GENE THERAPY; NEUROMUSCULAR REHABILITATION; NUCLEIC ACIDS;

ADENINE DEAMINASE; ADULT ANIMALS; DUCHENNE MUSCULAR DYSTROPHIES; POINT MUTATIONS; SINGLE NUCLEOTIDES; STREPTOCOCCUS PYOGENES; THERAPEUTIC POTENTIALS; TRANS-SPLICING;

MAMMALS;

ADENINE BASE EDITOR; ADENO ASSOCIATED VIRUS VECTOR; GUIDE RNA; MESSENGER RNA; NUCLEIC ACID BASE; UNCLASSIFIED DRUG; ADENINE; APO-DYSTROPHIN 1; DNA; DYSTROPHIN; MONOPHENOL MONOOXYGENASE;

ADULT; ALBINO MOUSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DUCHENNE MUSCULAR DYSTROPHY; EMBRYO; GENE EDITING; HUMAN; HUMAN CELL; MOUSE; MOUSE EMBRYO; MUSCLE CELL; NONHUMAN; NONSENSE MUTATION; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; TIBIALIS ANTERIOR MUSCLE; TRANS SPLICING; ALBINISM; ANIMAL; BIOTECHNOLOGY; CHEMISTRY; DEFICIENCY; DISEASE MODEL; EMBRYOLOGY; GENE THERAPY; GENETICS; HEK293 CELL LINE; KNOCKOUT MOUSE; MUTANT MOUSE STRAIN; NUCLEOTIDE SEQUENCE; PROCEDURES; TARGETED GENE REPAIR;

ADENINE; ALBINISM; ANIMALS; BASE SEQUENCE; BIOTECHNOLOGY; DISEASE MODELS, ANIMAL; DNA; DYSTROPHIN; GENE EDITING; GENETIC THERAPY; HEK293 CELLS; HUMANS; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MONOPHENOL MONOOXYGENASE; MUSCULAR DYSTROPHY, DUCHENNE; TARGETED GENE REPAIR;

EID: 85048365258     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.4148     Document Type: Article

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