-
1
-
-
0035902115
-
Proliferation, cell cycle and apoptosis in cancer
-
Evan GI, Vousden, KH: Proliferation, cell cycle and apoptosis in cancer. Nature 411(6835) 342-348 (2001).
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
2
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko LJ, Prives C: p53: puzzle and paradigm. Genes Dev. 10(9), 1054-1072 (1996).
-
(1996)
Genes Dev.
, vol.10
, Issue.9
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
3
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88(3), 323-331 (1997).
-
(1997)
Cell
, vol.88
, Issue.3
, pp. 323-331
-
-
Levine, A.J.1
-
4
-
-
0030969423
-
Fragments of ATM which have dominant-negative or complementing activity
-
Morgan SE, Lovly C, Pandita TK, Shiloh Y, Kastan MB: Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol. 17(4), 2020-2029 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, Issue.4
, pp. 2020-2029
-
-
Morgan, S.E.1
Lovly, C.2
Pandita, T.K.3
Shiloh, Y.4
Kastan, M.B.5
-
5
-
-
0037217583
-
TP53 and head and neck neoplasms
-
Blons H, Laurent-Puig P: TP53 and head and neck neoplasms. Hum. Mutat. 21(3), 252-257 (2003).
-
(2003)
Hum. Mutat.
, vol.21
, Issue.3
, pp. 252-257
-
-
Blons, H.1
Laurent-Puig, P.2
-
6
-
-
0027524636
-
The incidence of p53 mutations increases with progression of head and neck cancer
-
Boyle JO, Hakim J, Koch W et al.: The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res. 53(19), 4477-4480 (1993).
-
(1993)
Cancer Res.
, vol.53
, Issue.19
, pp. 4477-4480
-
-
Boyle, J.O.1
Hakim, J.2
Koch, W.3
-
7
-
-
0029783149
-
An uncertain role for p53 gene alterations in human prostate cancers
-
Brooks J, Bova G, Ewing C et al.: An uncertain role for p53 gene alterations in human prostate cancers. Cancer Res. 56(16) 3814-3822 (1996).
-
(1996)
Cancer Res.
, vol.56
, Issue.16
, pp. 3814-3822
-
-
Brooks, J.1
Bova, G.2
Ewing, C.3
-
8
-
-
0030754058
-
Primary human prostate cancer cells harbouring p53 mutations are clonally expanded in metastases
-
Stapleton A, Timme T, Gousse A et al.: Primary human prostate cancer cells harbouring p53 mutations are clonally expanded in metastases. Clin. Cancer Res. 3(8), 1389-1397 (1997).
-
(1997)
Clin. Cancer Res.
, vol.3
, Issue.8
, pp. 1389-1397
-
-
Stapleton, A.1
Timme, T.2
Gousse, A.3
-
9
-
-
0034566035
-
Adenoviral-mediated p53 transgene expression sensitizes both wild type and null p53 prostate cancer cells in vitro to radiation
-
Colletier PJ, Ashoori F, Cowen D et al.: Adenoviral-mediated p53 transgene expression sensitizes both wild type and null p53 prostate cancer cells in vitro to radiation. Int. J. Radiat. Oncol. Biol. Phys. 48 (5), 1507-1512 (2000).
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.48
, Issue.5
, pp. 1507-1512
-
-
Colletier, P.J.1
Ashoori, F.2
Cowen, D.3
-
10
-
-
0035164924
-
Clinical evaluation of adenoviral-mediated p53 gene transfer: Review of INGN 201 studies
-
Merritt JA, Roth JA, Logothetis CJ: Clinical evaluation of adenoviral-mediated p53 gene transfer: review of INGN 201 studies. Semin. Oncol. 28(5 Suppl. 16), 105-114 (2001).
-
(2001)
Semin. Oncol.
, vol.28
, Issue.5 SUPPL. 16
, pp. 105-114
-
-
Merritt, J.A.1
Roth, J.A.2
Logothetis, C.J.3
-
11
-
-
0035346819
-
Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): Results of Phase i and II trials
-
Kirn D: Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): results of Phase I and II trials. Expert Opin. Biol. Ther. 1(3), 525-538 (2001).
-
(2001)
Expert Opin. Biol. Ther.
, vol.1
, Issue.3
, pp. 525-538
-
-
Kirn, D.1
-
12
-
-
1542704139
-
Novel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy
-
Collis SJ, Khater K, DeWeese, TL: Novel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy. World J. Urol. 21(4), 275-289 (2003).
-
(2003)
World J. Urol.
, vol.21
, Issue.4
, pp. 275-289
-
-
Collis, S.J.1
Khater, K.2
Deweese, T.L.3
-
13
-
-
4644289015
-
Oncolytic viral therapies
-
Lin E, Nemunaitis J: Oncolytic viral therapies. Cancer Gene Thmer. 11(10), 643-664 (2004).
-
(2004)
Cancer Gene Thmer.
, vol.11
, Issue.10
, pp. 643-664
-
-
Lin, E.1
Nemunaitis, J.2
-
14
-
-
12244298187
-
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy
-
Swisher SG, Roth JA, Komaki R et al.: Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin. Cancer Res. 9(1), 93-101 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.1
, pp. 93-101
-
-
Swisher, S.G.1
Roth, J.A.2
Komaki, R.3
-
15
-
-
0035887153
-
A Phase i trial of CV706, a replicationcompetent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
-
DeWeese TL, van der Poel H, Li S et al.: A Phase I trial of CV706, a replicationcompetent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res. 61(20), 7464-7472 (2001).
-
(2001)
Cancer Res.
, vol.61
, Issue.20
, pp. 7464-7472
-
-
Deweese, T.L.1
Van Der Poel, H.2
Li, S.3
-
16
-
-
0346458886
-
Overview of Phase i studies of intravenous administration of PV701, an oncolytic virus
-
Lorence RM, Pecora AL, Major PP et al.: Overview of Phase I studies of intravenous administration of PV701, an oncolytic virus. Curr. Opin. Mol. Ther. 5(6), 618-624 (2003).
-
(2003)
Curr. Opin. Mol. Ther.
, vol.5
, Issue.6
, pp. 618-624
-
-
Lorence, R.M.1
Pecora, A.L.2
Major, P.P.3
-
17
-
-
84873471676
-
Safety of adenoviral vectors: Results of clinical investigations in 445 cancer patients treated with Advexin® (Adenoviral p53) gene therapy
-
Abstr. 1007, IN, USA
-
Zumstein L, Call D, Merritt J, Sobol RE, Menander, K: Safety of adenoviral vectors: results of clinical investigations in 445 cancer patients treated with Advexin® (Adenoviral p53) gene therapy in American Society of Cancer Gene Therapy Vol. Abstr. 1007, IN, USA (2004).
-
(2004)
American Society of Cancer Gene Therapy
-
-
Zumstein, L.1
Call, D.2
Merritt, J.3
Sobol, R.E.4
Menander, K.5
-
18
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
Nemunaitis J, Swisher SG, Timmons T et al.: Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J. Clin. Oncol. 18(3), 609-622 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, Issue.3
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
-
19
-
-
1842768380
-
China approves first gene therapy
-
Fox JL: China approves first gene therapy. Nature Biotechnol. 22(1), 3-4 (2004).
-
(2004)
Nature Biotechnol.
, vol.22
, Issue.1
, pp. 3-4
-
-
Fox, J.L.1
-
20
-
-
0027921638
-
Head and neck cancer
-
Vokes EE, Weichelbaum RR, Lippman SM, Hong WK: Head and neck cancer. New Engl. J. Med. 328, 84-194 (1993).
-
(1993)
New Engl. J. Med.
, vol.328
, pp. 84-194
-
-
Vokes, E.E.1
Weichelbaum, R.R.2
Lippman, S.M.3
Hong, W.K.4
-
21
-
-
1042295976
-
Clinical evaluation of safety and efficacy of intratumoral administration of a recombinant adenoviral-p53 anticancer agent (Genkaxin®)
-
Verma IM (Ed), Molecular Therapy, Elsevier, Inc., Washington DC, USA
-
Peng Z, Han D, Zhang S et al.: Clinical evaluation of safety and efficacy of intratumoral administration of a recombinant adenoviral-p53 anticancer agent (Genkaxin®). In The American Society of Gene Ther. Vol. 7(Suppl. 1), Verma IM (Ed), Molecular Therapy, Elsevier, Inc., Washington DC, USA, S422 (2003).
-
(2003)
The American Society of Gene Ther.
, vol.7
, Issue.SUPPL. 1
-
-
Peng, Z.1
Han, D.2
Zhang, S.3
-
22
-
-
0035576801
-
Additional gene therapy with Ad5CMV-p53 enhanced the efficacy of radiotherapy in human prostate cancer cells
-
Sasaki R, Shirakawa T, Zhang ZJ et al.: Additional gene therapy with Ad5CMV-p53 enhanced the efficacy of radiotherapy in human prostate cancer cells. Int. J. Radiat. Oncol. Biol. Phys. 51(5), 1336-1345 (2001).
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.51
, Issue.5
, pp. 1336-1345
-
-
Sasaki, R.1
Shirakawa, T.2
Zhang, Z.J.3
-
23
-
-
0033887419
-
The current status of gene therapy
-
Clayman GL: The current status of gene therapy. Semin.Oncol. 27(4 Suppl. 8), 39-43 (2000).
-
(2000)
Semin.Oncol.
, vol.27
, Issue.4 SUPPL. 8
, pp. 39-43
-
-
Clayman, G.L.1
-
24
-
-
0031025998
-
Gene therapy for cancer: What have we done and where are we going?
-
Roth J, Cristiano R: Gene therapy for cancer: what have we done and where are we going? J. Natl Cancer Inst. 89(1), 21-39 (1997).
-
(1997)
J. Natl Cancer Inst.
, vol.89
, Issue.1
, pp. 21-39
-
-
Roth, J.1
Cristiano, R.2
-
25
-
-
0032809839
-
Adenovirus-mediated wild type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
-
Clayman GL, Frank DK, Bruso PA, Goepfert H: Adenovirus-mediated wild type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin. Cancer Res. 5(7), 1715-1722 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, Issue.7
, pp. 1715-1722
-
-
Clayman, G.L.1
Frank, D.K.2
Bruso, P.A.3
Goepfert, H.4
-
26
-
-
0032990031
-
Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer
-
Gurnani M, Lipari P, Dell J, Shi B, Nielsen LL: Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer. Cancer Chemother. Pharmacol. 44(2), 143-151 (1999).
-
(1999)
Cancer Chemother. Pharmacol.
, vol.44
, Issue.2
, pp. 143-151
-
-
Gurnani, M.1
Lipari, P.2
Dell, J.3
Shi, B.4
Nielsen, L.L.5
-
27
-
-
0037214560
-
Gene therapy for the treatment of oral squamous cell carcinoma
-
Xi S, Grandis JR: Gene therapy for the treatment of oral squamous cell carcinoma. J. Dent. Res. 82(1), 11-16 (2003).
-
(2003)
J. Dent. Res.
, vol.82
, Issue.1
, pp. 11-16
-
-
Xi, S.1
Grandis, J.R.2
-
28
-
-
0031750168
-
Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
-
Clayman GL, el-Naggar AK, Lippman SM et al.: Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J. Clin. Oncol. 16(6), 2221-2232 (1998).
-
(1998)
J. Clin. Oncol.
, vol.16
, Issue.6
, pp. 2221-2232
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Lippman, S.M.3
-
29
-
-
0006596907
-
Randomized Phase II study of intratumoral injection of two dosing schedules using a replication-deficient adenovirus carrying the p53 gene (AD5CMV-P53) in patients with recurrent/refractory head and neck cancer
-
Goodwin WJ, Esser D, Clayman GL, Al E: Randomized Phase II study of intratumoral injection of two dosing schedules using a replication-deficient adenovirus carrying the p53 gene (AD5CMV-P53) in patients with recurrent/refractory head and neck cancer. Proc. Am. Soc. Clin. Oncol. 18, 445a (1999).
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Goodwin, W.J.1
Esser, D.2
Clayman, G.L.3
-
30
-
-
0033218746
-
Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: Intratumoral spread and distribution effects
-
Heise C, Williams A, Olesch J, Kirn D: Efficacy of a replication- competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects. Cancer Gene Ther. 6, 499-504 (1999).
-
(1999)
Cancer Gene Ther.
, vol.6
, pp. 499-504
-
-
Heise, C.1
Williams, A.2
Olesch, J.3
Kirn, D.4
-
31
-
-
0033665576
-
Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status
-
Heise C, Ganly I, Kim YT et al.: Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status. Gene Ther. 7(22), 1925-1929 (2000).
-
(2000)
Gene Ther.
, vol.7
, Issue.22
, pp. 1925-1929
-
-
Heise, C.1
Ganly, I.2
Kim, Y.T.3
-
32
-
-
12944328660
-
A Phase i study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
-
[Erratum appears in Clin. Cancer. Res. 6(5), 2120 (2000). Note: Eckhardt SG [corrected to Eckhardt G]
-
Ganly I, Kirn D, Eckhardt G et al.: A Phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. [Erratum appears in Clin. Cancer. Res. 6(5), 2120 (2000). Note: Eckhardt SG [corrected to Eckhardt G]. Clin. Cancer Res. 6(3), 798-806 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, Issue.3
, pp. 798-806
-
-
Ganly, I.1
Kirn, D.2
Eckhardt, G.3
-
33
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A Phase II trial
-
Nemunaitis J, Ganly I, Khuri F et al.: Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a Phase II trial. Cancer Res. 60(22), 6359-6366 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.22
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
34
-
-
12444281703
-
Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients
-
Nemunaitis J, Cunningham C, Tong AW et al.: Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients. Cancer Gene Ther. 10(5), 341-352 (2003).
-
(2003)
Cancer Gene Ther.
, vol.10
, Issue.5
, pp. 341-352
-
-
Nemunaitis, J.1
Cunningham, C.2
Tong, A.W.3
-
35
-
-
0034077666
-
Replication-selective adenoviruses as oncolytic agents
-
Heise C, Kirn, DH: Replication-selective adenoviruses as oncolytic agents. J. Clin. Invest. 105(7), 847-851 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, Issue.7
, pp. 847-851
-
-
Heise, C.1
Kirn, D.H.2
-
36
-
-
0029985110
-
Tumor suppressive properties of the adenovirus 5 E1A oncogene
-
Mymryk JS: Tumor suppressive properties of the adenovirus 5 E1A oncogene. Oncogene 13(8), 1581-1589 (1996).
-
(1996)
Oncogene
, vol.13
, Issue.8
, pp. 1581-1589
-
-
Mymryk, J.S.1
-
37
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5- fluorouracil in patients with recurrent head and neck cancer [see comment]
-
Khuri FR, Nemunaitis J, Ganly I et al.: A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5- fluorouracil in patients with recurrent head and neck cancer [see comment]. Nature Med. 6(8), 879-885 (2000).
-
(2000)
Nature Med.
, vol.6
, Issue.8
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
38
-
-
0034907553
-
Phase i trial of intratumoral liposome E1A gene therapy in patients with recurrent breast and head and neck cancer
-
Yoo GH, Hung MC, Lopez-Berestein G et al.: Phase I trial of intratumoral liposome E1A gene therapy in patients with recurrent breast and head and neck cancer. Clin. Cancer Research 7(5), 1237-1245 (2001).
-
(2001)
Clin. Cancer Research
, vol.7
, Issue.5
, pp. 1237-1245
-
-
Yoo, G.H.1
Hung, M.C.2
Lopez-Berestein, G.3
-
39
-
-
0037112449
-
Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene
-
Ueno NT, Bartholomeusz C, Xia W et al.: Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene. Cancer Res. 62(22), 6712-6716 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.22
, pp. 6712-6716
-
-
Ueno, N.T.1
Bartholomeusz, C.2
Xia, W.3
-
40
-
-
0036569510
-
Phase i trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers [see comment]
-
Pecora AL, Rizvi N, Cohen GI et al.: Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers [see comment]. J. Clin. Oncol. 20(9), 2251-2266 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, Issue.9
, pp. 2251-2266
-
-
Pecora, A.L.1
Rizvi, N.2
Cohen, G.I.3
-
41
-
-
0035863499
-
Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
-
Yu DC, Chen Y, Dilley J et al.: Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res. 61(2), 517-525, (2001).
-
(2001)
Cancer Res.
, vol.61
, Issue.2
, pp. 517-525
-
-
Yu, D.C.1
Chen, Y.2
Dilley, J.3
-
42
-
-
0036733759
-
Phase i study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer
-
Freytag SO, Khil M, Stricker H et al.: Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res. 62(17), 4968-4976 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.17
, pp. 4968-4976
-
-
Freytag, S.O.1
Khil, M.2
Stricker, H.3
-
43
-
-
3543114272
-
Biologically active sphingolipids in cancer pathogenesis and treatment
-
Ogretmen B, Hannun YA: Biologically active sphingolipids in cancer pathogenesis and treatment. Nature Rev. Cancer 4(8), 604-616 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, Issue.8
, pp. 604-616
-
-
Ogretmen, B.1
Hannun, Y.A.2
-
44
-
-
0033839592
-
Human acid ceramidase is overexpressed but not mutated in prostate cancer
-
Seelan RS, Qian C, Yokomizo A et al.: Human acid ceramidase is overexpressed but not mutated in prostate cancer. Genes Chrom. Cancer 29(2), 137-146 (2000).
-
(2000)
Genes Chrom. Cancer
, vol.29
, Issue.2
, pp. 137-146
-
-
Seelan, R.S.1
Qian, C.2
Yokomizo, A.3
-
45
-
-
0035854766
-
Cloning and characterization of a novel human alkaline ceramidase - A mammalian enzyme that hydrolyzes phytoceramide
-
Mao CG, Xu RJ, Szulc ZM et al.: Cloning and characterization of a novel human alkaline ceramidase - a mammalian enzyme that hydrolyzes phytoceramide. J. Biol. Chem. 276(28), 26577-26588 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.28
, pp. 26577-26588
-
-
Mao, C.G.1
Xu, R.J.2
Szulc, Z.M.3
-
46
-
-
0030479325
-
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease
-
Koch J, Gartner S, Li CM et al.: Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease. J. Biol. Chem. 271(51), 33110-33115 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.51
, pp. 33110-33115
-
-
Koch, J.1
Gartner, S.2
Li, C.M.3
-
47
-
-
0033600850
-
Purification and characterization of a membrane-bound nonlysosomal ceramidase from rat brain
-
El Bawab S, Bielawska A, Hannun YA: Purification and characterization of a membrane-bound nonlysosomal ceramidase from rat brain. J. Biol. Chem. 274(39), 27948-27955 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.39
, pp. 27948-27955
-
-
El Bawab, S.1
Bielawska, A.2
Hannun, Y.A.3
-
48
-
-
0034647935
-
Molecular cloning and characterization of a human mitochondrial ceramidase
-
El Bawab S, Roddy P, Qian T et al.: Molecular cloning and characterization of a human mitochondrial ceramidase. J. Biol. Chem. 275(28), 21508-21513 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.28
, pp. 21508-21513
-
-
El Bawab, S.1
Roddy, P.2
Qian, T.3
-
49
-
-
0035740250
-
Chromosomal deletions and tumor suppressor genes in prostate cancer
-
Dong JT: Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Met. Rev. 20(3-4), 173-193 (2001).
-
(2001)
Cancer Met. Rev.
, vol.20
, Issue.3-4
, pp. 173-193
-
-
Dong, J.T.1
-
50
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee MJ, Van Brocklyn JR, Thangada S et al.: Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279(5356), 1552-1555 (1998).
-
(1998)
Science
, vol.279
, Issue.5356
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
-
51
-
-
0034605034
-
Overexpression of acid ceramidase protects from tumor necrosis factorinduced cell death
-
Strelow A, Bernardo K, Adam-Klages S et al.: Overexpression of acid ceramidase protects from tumor necrosis factorinduced cell death. J. Exp. Med. 192(5), 601-612 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, Issue.5
, pp. 601-612
-
-
Strelow, A.1
Bernardo, K.2
Adam-Klages, S.3
-
52
-
-
0034296761
-
Intracellular Fas ligand expression causes Fas-mediated apoptosis in human prostate cancer cells resistant to monoclonal antibody-induced apoptosis
-
Hyer ML, Voelkel-Johnson C, Rubinchik S, Dong J, Norris JS: Intracellular Fas ligand expression causes Fas-mediated apoptosis in human prostate cancer cells resistant to monoclonal antibody-induced apoptosis. Mol.Ther. 2(4), 348-358 (2000).
-
(2000)
Mol.Ther.
, vol.2
, Issue.4
, pp. 348-358
-
-
Hyer, M.L.1
Voelkel-Johnson, C.2
Rubinchik, S.3
Dong, J.4
Norris, J.S.5
-
53
-
-
1842843211
-
Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fasmediated apoptosis
-
Hyer ML, Sudarshan S, Kim Y et al.: Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fasmediated apoptosis. Cancer Biology Ther. 1(4), 348-358 (2002).
-
(2002)
Cancer Biology Ther.
, vol.1
, Issue.4
, pp. 348-358
-
-
Hyer, M.L.1
Sudarshan, S.2
Kim, Y.3
-
54
-
-
0035342127
-
The use of Fas Ligand, TRAIL and Bax in gene therapy of prostate cancer
-
Norris JS, Hyer ML, Voelkel-Johnson C et al.: The use of Fas Ligand, TRAIL and Bax in gene therapy of prostate cancer. Curr. Gene Ther. 1(1), 123-136 (2001).
-
(2001)
Curr. Gene Ther.
, vol.1
, Issue.1
, pp. 123-136
-
-
Norris, J.S.1
Hyer, M.L.2
Voelkel-Johnson, C.3
-
55
-
-
33746180010
-
Ceramide, ceramidase and FasL gene therapy in prostate cancer
-
El-Deiry WS (Ed.), Humana Press, Inc., NJ, USA, In Press
-
Norris JS, Holman DH, Hyer ML et al.: Ceramide, Ceramidase and FasL Gene Therapy in Prostate Cancer. In:Death Receptors in Cancer Therapy, Vol. El-Deiry WS (Ed.), Humana Press, Inc., NJ, USA (2004) In Press.
-
(2004)
Death Receptors in Cancer Therapy
-
-
Norris, J.S.1
Holman, D.H.2
Hyer, M.L.3
-
56
-
-
42549096708
-
Pro-apoptotic strategy in cancer gene therapy
-
(Eds.) Curiel DT, Douglas J Humana Press, Inc., NJ, USA
-
Holman DH, Hyer ML, El-Zawahry AM, Keller GM & Norris JS. Pro-apoptotic Strategy in Cancer Gene Therapy. In Cancer Gene Therapy (Eds.) Curiel DT, Douglas J Humana Press, Inc., NJ, USA (2003).
-
(2003)
Cancer Gene Therapy
-
-
Holman, D.H.1
Hyer, M.L.2
El-Zawahry, A.M.3
Keller, G.M.4
Norris, J.S.5
-
57
-
-
0037384316
-
Quantification and characterization of the bystander effect in prostate cancer cells following adenovirus-mediated FasL expression
-
Hyer ML, Sudarshan S, Schwartz DA et al.: Quantification and characterization of the bystander effect in prostate cancer cells following adenovirus-mediated FasL expression. Cancer Gene Ther. 10(4), 330-339 (2003).
-
(2003)
Cancer Gene Ther.
, vol.10
, Issue.4
, pp. 330-339
-
-
Hyer, M.L.1
Sudarshan, S.2
Schwartz, D.A.3
-
58
-
-
0035191647
-
A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression
-
Rubinchik S, Wang D, Yu H et al.: A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression. Mol. Ther. 4(5), 416-426 (2001).
-
(2001)
Mol. Ther.
, vol.4
, Issue.5
, pp. 416-426
-
-
Rubinchik, S.1
Wang, D.2
Yu, H.3
-
59
-
-
84858432693
-
Molecular biology, nucleic acids, and the future of medicine
-
Lyght CE (Ed.), McGraw-Hill, NY, USA
-
Tatum EL: Molecular Biology, Nucleic Acids, and the Future of Medicine. In Reflections on Research and the Future of Medicine Lyght CE (Ed.), McGraw-Hill, NY, USA. 31-49 (1967).
-
(1967)
Reflections on Research and the Future of Medicine
, pp. 31-49
-
-
Tatum, E.L.1
-
60
-
-
0028807727
-
T lymphocyte-directed gene therapy for ADASCID: Initial trial results after 4 years
-
Blaese RM, Culver KW Miller, AD et al.: T lymphocyte-directed gene therapy for ADASCID: initial trial results after 4 years. Science 270(5235), 475-480 (1995).
-
(1995)
Science
, vol.270
, Issue.5235
, pp. 475-480
-
-
Blaese, R.M.1
Culver, K.W.2
Miller, A.D.3
-
61
-
-
0033974782
-
Ceramide in the eukaryotic stress response
-
Hannun YA, Luberto C. Ceramide in the eukaryotic stress response. Trends Cell Biol. 10(2), 73-80 (2000).
-
(2000)
Trends Cell Biol.
, vol.10
, Issue.2
, pp. 73-80
-
-
Hannun, Y.A.1
Luberto, C.2
-
62
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Hannun YA: Functions of ceramide in coordinating cellular responses to stress. Science 274(5294) 1855-1859 (1996).
-
(1996)
Science
, vol.274
, Issue.5294
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
63
-
-
84873474062
-
-
Accessed January 2005
-
http://p53.curie.fr/p53%20site%20version%202.0/p53%20in%20cancer/ p53-databaseANAL.html (Accessed January 2005)
-
-
-
-
64
-
-
84873455252
-
-
Accessed January 2005
-
www.georgetown.edu/research/nrcbl/publications/scopenotes/sn24.htm (Accessed January 2005)
-
-
-
|