Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism

Hepatology

Volumn 68, Issue 4, 2018, Pages 1574-1588

  Pathak, Preeti ^a   Xie, Cen ^b   Nichols, Robert G ^c   Ferrell, Jessica M ^a   Boehme, Shannon ^a   Krausz, Kristopher W ^b   Patterson, Andrew D ^c   Gonzalez, Frank J ^b   Chiang, John Y L ^a  

^a Northeast Ohio Medical University   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; FARNESOID X RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; FIBROBLAST GROWTH FACTOR 21; G PROTEIN BILE ACID RECEPTOR 1; GLUCAGON LIKE PEPTIDE 1; RECEPTOR; RNA 16S; TAUROLITHOCHOLIC ACID; UNCLASSIFIED DRUG; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN;

ACETATIFACTOR; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANTIBIOTIC THERAPY; ARTICLE; BACTEROIDES; BILE ACID SYNTHESIS; GENE EXPRESSION; INSULIN SENSITIVITY; INTESTINE FLORA; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; LIPID METABOLISM; METABOLISM; RANDOMIZATION; SENSITIVITY AND SPECIFICITY;

ANIMALS; BILE ACIDS AND SALTS; DISEASE MODELS, ANIMAL; GASTROINTESTINAL MICROBIOME; GLUCAGON-LIKE PEPTIDE 1; GTP-BINDING PROTEINS; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, G-PROTEIN-COUPLED; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 85047397102     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.29857     Document Type: Article

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