Preparation of drug-loaded small unilamellar liposomes and evaluation of their potential for the treatment of chronic respiratory diseases

International Journal of Pharmaceutics

Volumn 545, Issue 1-2, 2018, Pages 378-388

  De Leo, Vincenzo ^a,b   Ruscigno, Silvia ^a   Trapani, Adriana ^a   Di Gioia, Sante ^c   Milano, Francesco ^b   Mandracchia, Delia ^a   Comparelli, Roberto ^b   Castellani, Stefano ^c   Agostiano, Angela ^a,b   Trapani, Giuseppe ^a   Catucci, Lucia ^a,b   Conese, Massimo ^c  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF FOGGIA   (Italy)

Author keywords

Bechlometasone dipropionate; COPD patient mucus penetration; Cytotoxicity; Drug loaded liposomes; Micelle to vesicle transition method; Pulmonary delivery

Indexed keywords

BECLOMETASONE DIPROPIONATE; DRUG CARRIER; LIPOSOME; BECLOMETASONE; GLUCOCORTICOID; LIPID; MACROGOL; MACROGOL 2000; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOFLUOROMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; LUNG LAVAGE; MOUSE; MTT ASSAY; NCI-H441 CELL LINE; NONHUMAN; PRIORITY JOURNAL; SPUTUM; AEROSOL; ANIMAL; CELL LINE; CHEMISTRY; DRUG STABILITY; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; MUCUS; PERMEABILITY; PHARMACEUTICS; PROCEDURES; SURFACE PROPERTY;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; BECLOMETHASONE; CELL LINE; DRUG COMPOUNDING; DRUG STABILITY; GLUCOCORTICOIDS; HUMANS; LIPIDS; LIPOSOMES; MICE; MUCUS; PERMEABILITY; POLOXAMER; POLYETHYLENE GLYCOLS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SPUTUM; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 85047265895     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2018.04.030     Document Type: Article

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