Nano-carrier systems: Strategies to overcome the mucus gel barrier

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 96, Issue , 2015, Pages 447-453

  Dunnhaupt S ^a   Kammona, O ^c   Waldner, C ^a   Kiparissides, C ^b,c   Bernkop Schnurch A ^d  

^a Thiomatrix Forschungs und Beratungs GmbH   (Austria)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c INFORMATION TECHNOLOGIES INSTITUTE   (Greece)

^d UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Back diffusion; Innovative strategies; Mucus barrier; Mucus penetration; Nanocarriers; Proteolytic enzymes

Indexed keywords

BROMELAIN; CYSTEINE; DISULFIDE; NANOCARRIER; PAPAIN; PROTEINASE; THIOL GROUP; DRUG CARRIER; EMULSION; EXPECTORANT AGENT; NANOMATERIAL; PEPTIDE HYDROLASE;

DRUG DELIVERY SYSTEM; HUMAN; MUCUS; NANOEMULSION; REVIEW; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; SURFACE PROPERTY; ZETA POTENTIAL; ABSORPTION; ANIMAL; CHEMISTRY; DIFFUSION; DRUG EFFECTS; EMULSION; METABOLISM; MUCOSA; PERMEABILITY; PH; PHARMACOKINETICS; PROTEIN DEGRADATION; SECRETION (PROCESS); TRENDS;

ABSORPTION, PHYSIOLOGICAL; ANIMALS; DIFFUSION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; EXPECTORANTS; HUMANS; HYDROGEN-ION CONCENTRATION; MUCOUS MEMBRANE; MUCUS; NANOSTRUCTURES; PEPTIDE HYDROLASES; PERMEABILITY; PHARMACOKINETICS; PROTEOLYSIS; SURFACE PROPERTIES;

EID: 84946712632     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.01.022     Document Type: Review

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