On the synthesis of mucus permeating nanocarriers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 97, Issue , 2015, Pages 239-249

  Bourganis, Vassilis ^a   Karamanidou, Theodora ^a   Samaridou, Eleni ^a   Karidi, Konstantina ^b   Kammona, Olga ^b   Kiparissides, Costas ^a,b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b INFORMATION TECHNOLOGIES INSTITUTE   (Greece)

Author keywords

4 Mercaptobenzoic acid; Liposomes; Mucosa; Oral delivery; Poly(lactide co glycolide) nanoparticles; Polyelectrolyte complexes; Polyethylene glycol

Indexed keywords

4 MERCAPTOBENZOIC ACID; LIPOSOME; MACROGOL; MUCOLYTIC AGENT; NANOCARRIER; POLYACRYLIC ACID; POLYARGININE; POLYCATION; POLYGLACTIN; UNCLASSIFIED DRUG; 4-MERCAPTOBENZOATE; BENZOIC ACID DERIVATIVE; DELAYED RELEASE FORMULATION; DRUG CARRIER; EXPECTORANT AGENT; MACROGOL DERIVATIVE; NANOPARTICLE; PHOSPHOLIPID; POLY(LACTIC-GLYCOLIC ACID)-POLY(ETHYLENEGLYCOL) COPOLYMER; POLYMER; THIOL DERIVATIVE;

ARTICLE; CONTROLLED DRUG RELEASE; MOLECULAR SIZE; MOLECULAR WEIGHT; MUCUS; NANOENCAPSULATION; NONHUMAN; PERMEABILITY; PHOSPHOLIPID BILAYER; PIG; SURFACE CHARGE; SYNTHESIS; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DRUG RELEASE; MEDICINAL CHEMISTRY; METABOLISM; PARTICLE SIZE; PROCEDURES;

ANIMALS; BENZOATES; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG LIBERATION; EXPECTORANTS; LIPOSOMES; MOLECULAR WEIGHT; MUCUS; NANOPARTICLES; PARTICLE SIZE; PERMEABILITY; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; POLYMERS; SULFHYDRYL COMPOUNDS; SWINE;

EID: 84946722479     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.01.021     Document Type: Article

References (47)

1. S.K. Lai, Y.-Y. Wang, and J. Hanes Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues Adv. Drug Delivery Rev. 61 2009 158 171
2. M. Müller, B. Keßler, J. Fröhlich, S. Poeschla, and B. Torger Polyelectrolyte complex nanoparticles of poly(ethyleneimine) and poly(acrylic acid): preparation and applications Polymers 3 2 2011 762 778
3. T. Delair Colloidal polyelectrolyte complexes of chitosan and dextran sulfate towards versatile nanocarriers of bioactive molecules Eur. J. Pharm. Biopharm. 78 1 2011 10 18
4. A.F. Thünemann, M. Müller, H. Dautzenberg, J.F. Joanny, and H. Löwen Polyelectrolyte complexes Adv. Polym. Sci. 166 2004 113 171
5. Y.-Y. Wang, S.K. Lai, J.S. Suk, A. Pace, R. Cone, and J. Hanes Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier Angew. Chem. Int. Ed. 47 2008 9726 9729
6. Y. Cu, and W.M. Saltzman Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus Mol. Pharm. 6 1 2009 173 181
7. T. Yu, Y.-Y. Wang, M. Yang, C. Schneider, W. Zhong, S. Pulicare, W.-J. Choi, O. Mert, J. Fu, S.K. Lai, and J. Hanes Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid) Drug Delivery Transl. Res. 2 2012 124 128
8. F. Laffleur, F. Hintzen, G. Shahnaz, D. Rahmat, K. Leithner, and A. Bernkop-Schnürch Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus Nanomedicine 2013 10.2217/nnm.13.26
9. M.O. Henke, and F. Ratjen Mucolytics in cystic fibrosis Paediatr. Respir. Rev. 8 1 2007 24 29
10. J.S. Suk, S.K. Lai, N.J. Boylan, M.R. Dawson, M.P. Boyle, and J. Hanes Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine Nanomedicine (Lond.) 6 2 2011 365 375
11. J.S. Suk, N.J. Boylan, K. Trehan, B.C. Tang, C.S. Schneider, J.-M.G. Lin, M.P. Boyle, P.L. Zeitlin, S.K. Lai, M.J. Cooper, and J. Hanes N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles Mol. Ther. 19 11 2011 1981 1989
12. V. Sanna, G. Pintus, A.M. Roggio, S. Punzoni, A.M. Posadino, A. Arca, S. Marceddu, P. Bandiera, S. Uzzau, and M. Sechi Targeted biocompatible nanoparticles for the delivery of (-)-epigallocatechin 3-gallate to prostate cancer cells J. Med. Chem. 54 2011 1321 1332
13. T. Betancourt, Targetable Biodegradable Nanoparticles for Delivery of Chemotherapeutic and Imaging Agents to Ovarian Cancer, PhD Dissertation, The University of Texas at Austin, 2007.
14. C.W. Liu, and W.J. Lin Polymeric nanoparticles conjugate a novel heptapeptide as an epidermal growth factor receptor-active targeting ligand for doxorubicin Int. J. Nanomedicine 7 2012 4749 4767
15. S. Hamdy, A. Haddadi, V. Somayaji, D. Ruan, and J. Samuel Pharmaceutical analysis of synthetic lipid A-based vaccine adjuvants in poly(d,l-lactic-co-glycolic acid) nanoparticle formulations J. Pharm. Biomed. Anal. 44 2007 914 923
16. J.L. Perry, K.G. Reuter, M.P. Kai, K.P. Herlihy, S.W. Jones, J.C. Luft, M. Napier, and J.E. Bear PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics Nano Lett. 12 2012 5304 5310
17. R. Gref, M. Luck, P. Quellec, M. Marchand, E. Dellacherie, S. Harnisch, T. Blunk, and R.H. Müller "Stealth" corona-core nanoparticles surface modified by polyethylene glycol (Peg): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption Colloid Surf. B 18 2000 301 313
18. M. Müller, T. Reihs, and W. Ouyang Needlelike and spherical polyelectrolyte complex nanoparticles of poly(L-lysine) and copolymers of maleic acid Langmuir 21 2005 465 469
19. L. Leclercq, M. Boustta, J. Rixte, and M. Vert Degradability of poly(L-lysine) and poly(DL-aminoserinate) complexed with a polyanion under conditions modelling physico-chemical characteristics of body fluids J. Colloid Interf. Sci. 350 2010 459 464
20. S. Dadashzadeh, N. Mirahmadi, M.H. Babaei, and A.M. Vali Peritoneal retention of liposomes: effects of lipid composition, PEG coating and liposome charge J. Control. Release 148 2010 177 186
21. F. Sampedro, J. Partika, P. Santalo, A.M. Molins-Pujol, J. Bonal, and R. Perez-Soler Liposomes as carriers of different new lipophilic antitumour drugs: a preliminary report J. Microencapsul. 11 3 1994 309 318
22. F. Lindström, M. Bokvist, T. Sparrman, and G. Gröbner Association of amyloid-b peptide with membrane surfaces monitored by solid state NMR Phys. Chem. Chem. Phys. 4 2002 5524 5530
23. A. Pantos, Z. Sideratou, and C.M. Paleos Complementary liposomes based on phosphatidylcholine: interaction effectiveness vs protective coating J. Colloid Interf. Sci. 253 2002 435 442
24. F. Sarti, G. Perera, F. Hintzen, K. Kotti, V. Karageorgiou, O. Kammona, C. Kiparissides, and A. Bernkop-Schnürch In vivo evidence of oral vaccination with PLGA nanoparticles containing the immunostimulant monophosphoryl lipid A Biomaterials 32 2011 4052 4057
25. P. Panwar, B. Pandey, P.C. Lakhera, and K.P. Singh Preparation, characterization, and in vitro release study of albendazole-encapsulated nanosize liposomes Int. J. Nanomedicine 5 2010 101 108
26. T. Tsukamoto, K. Hironaka, T. Fujisawa, D. Yamaguchi, K. Tahara, Y. Tozuka, and H. Takeuchi Preparation of bromfenac-loaded liposomes modified with chitosan for ophthalmic drug delivery and evaluation of physicochemical properties and drug release profile Asian J. Pharm. Sci. 8 2 2013 104 109
27. H. Friedl, S. Dunnhaupt, F. Hintzen, C. Waldner, S. Parikh, J.P. Pearson, M.D. Wilcox, and A. Bernkop-Schnürch Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery systems J. Pharm. Sci. 102 12 2013 4406 4413
28. J. Kazzaz, M. Singh, M. Ugozzoli, J. Chesko, E. Soenawan, and D.T. O'Hagan Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potency J. Control. Release 110 2006 566 573
29. Y. Li, Y. Pei, X. Zhang, Z. Gu, Z. Zhou, W. Yuan, J. Zhou, J. Zhu, and X. Gao PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats J. Control. Release 71 2001 203 211
30. L.M. Ensign, C. Schneider, J.S. Suk, R. Cone, and J. Hanes Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery Adv. Mater. 24 2012 3887 3894
31. D.E. Owens, and N.A. Peppas Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles Int. J. Pharm. 307 2006 93 102
32. S.M. Hartig, G. Carlesso, J.M. Davidson, and A. Prokop Development of improved nanoparticulate polyelectrolyte complex physicochemistry by nonstoichiometric mixing of polyions with similar molecular weights Biomacromolecules 8 1 2007 265 272
33. F.A. Oyarzun-Ampuero, F.M. Goycoolea, D. Torres, and M.J. Alonso A new drug nanocarrier consisting of polyarginine and hyaluronic acid Eur. J. Pharm. Biopharm. 79 2011 54 57
34. T. Takahashi, K. Takayama, Y. Machida, and T. Nagai Characteristics of polyion complexes of chitosan with sodium alginate and sodium polyacrylate Int. J. Pharm. 61 1990 35 41
35. Y. Chen, V.J. Mohanraj, F. Wang, and H.A.E. Benson Designing chitosan-dextran sulfate nanoparticles using charge ratios AAPS PharmSciTech 8 4 2007 131 139
36. G. Mittal, D.K. Sahana, V. Bhardwaj, and M.N.V. Ravi Kumar Estradiol loaded PLGA nanoparticles for oral administration: effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo J. Control. Release 119 2007 77 85
37. S. Sriwongsitanont, and M. Ueno Effect of a PEG lipid (DSPEPEG2000) and freeze-thawing process on phospholipid vesicle size and lamellarity Colloid Polym. Sci. 2004 753 760
38. C.C. Muller-Goymann Physicochemical characterisation of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration Eur. J. Pharm. Biopharm. 58 2004 343 356
39. R.A. Schwendener, H. Schott, Liposome formulations of hydrophobic drugs, in: V. Weissig (Ed.), Liposomes Methods and Protocols, vol. 1: Pharmaceutical Nanocarriers, Series: Liposomes Methods in Molecular Biology, vol. 605, Humana Press, 2010, pp. 129-138.
40. K. Bowey, J.-F. Tanguay, and M. Tabrizian 2-Dioleoyl-sn-glycero-3-phosphocholine-based nanoliposomes5 as an effective delivery platform for 17b-estradiol Eur. J. Pharm. Biopharm. 86 2014 369 375
41. L.H. Lindner, and M. Hossann Factors affecting drug release from liposomes Curr. Opin. Drug Discov. Dev. 13 1 2010 111 123
42. M. Anderson, and A. Omri The effect of different lipid components on the in vitro stability and release kinetics of liposome formulations Drug Delivery 11 2004 33 39
43. M. Grit, and D. Crommelin Chemical stability of liposomes: implications for their physical stability Chem. Phys. Lipids 64 1-3 1993 3 18
44. M.M. Nounou, L.K. El-Khordagui, N.A. Khalafallah, and S.A. Kkhalil In vitro release of hydrophilic and hydrophobic drugs from liposomal dispersions and gels Acta Pharm. 56 2006 311 324
45. Q. Xu, N.J. Boylan, C. Shutian, B. Miao, H. Patel, and J. Hanes Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus J. Control. Release 170 2013 279 286
46. D.N. Granger, P.R. Kvietys, M.A. Perry, and A.E. Taylor Charge selectivity of rat intestinal capillaries. Influence of polycations Gastroenterology 91 1986 1443 1446
47. J. Hanes, K. Wai Y. Chan, M.T. Mcmahon, M. Yang, T. Yu, Lipid-based Drug Carriers for Rapid Penetration through Mucus Linings, WO2013166498, Patent.