Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery Systems

Journal of Pharmaceutical Sciences

Volumn 102, Issue 12, 2013, Pages 4406-4413

  Friedl, Heike ^a   Dünnhaupt, Sarah ^a   Hintzen, Fabian ^b   Waldner, Claudia ^a   Parikh, Shruti ^c   Pearson, Jeffrey P ^c   Wilcox, Matthew D ^c   Bernkop Schnürch, Andreas ^b  

^a Thiomatrix Forschungs und Beratungs GmbH   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

diffusion; nanoparticles; particle size; self emulsifying; solubility; surfactants

Indexed keywords

BUFFER; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; DIPOTASSIUM HYDROGEN PHOSPHATE; EMULSIFYING AGENT; EXCIPIENT; FLUORESCEIN DIACETATE; GLYCEROL; MACROGOL 400; OCTANOIN; OLEIC ACID ETHYL ESTER; POLYSORBATE 60; POLYSORBATE 80; SODIUM DIHYDROGEN PHOSPHATE; TRIACETIN;

ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; MICROSCOPY; MUCUS; MUCUS DIFFUSION TEST; NANOEMULSION; PARTICLE SIZE; PROTEIN SECRETION; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; SMALL INTESTINE MUCOSA;

DIFFUSION; NANOPARTICLES; PARTICLE SIZE; SELF-EMULSIFYING; SOLUBILITY; SURFACTANTS;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DIFFUSION; DRUG DELIVERY SYSTEMS; EMULSIFYING AGENTS; EMULSIONS; FLUORESCEINS; INTESTINAL MUCOSA; NANOPARTICLES; SOLUBILITY; SURFACE-ACTIVE AGENTS; SWINE;

EID: 84888203026     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23757     Document Type: Article

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