메뉴 건너뛰기




Volumn 34, Issue 13, 2013, Pages 3439-3446

Nanoparticle diffusion in respiratory mucus from humans without lung disease

Author keywords

Inhaled nanoparticles; Mucus penetrating particles; Multiple particle tracking; Respiratory mucus; Rheology

Indexed keywords

AIRWAY EPITHELIUM; BARRIER PROPERTIES; COMORBIDITIES; DESIGN CRITERIA; HEALTH IMPLICATIONS; INHALED PARTICLES; LOW MOLECULAR WEIGHT POLYETHYLENES; MACROSCOPIC LEVELS; MUCUS-PENETRATING PARTICLES; MULTIPLE PARTICLE TRACKING; PARTICLE SIZE AND SURFACES; POLYMERIC NANOPARTICLES; RESPIRATORY MUCUS; SURGICAL PATIENTS; VISCOELASTIC SOLIDS; VISCOUS LIQUIDS;

EID: 84874239794     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.064     Document Type: Article
Times cited : (352)

References (45)
  • 1
    • 84865305392 scopus 로고    scopus 로고
    • A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
    • Button B., Cai L.H., Ehre C., Kesimer M., Hill D.B., Sheehan J.K., et al. A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science 2012, 337:937-941.
    • (2012) Science , vol.337 , pp. 937-941
    • Button, B.1    Cai, L.H.2    Ehre, C.3    Kesimer, M.4    Hill, D.B.5    Sheehan, J.K.6
  • 2
    • 78649735324 scopus 로고    scopus 로고
    • Airway mucus function and dysfunction
    • Fahy J.V., Dickey B.F. Airway mucus function and dysfunction. N Engl J Med 2010, 363:2233-2247.
    • (2010) N Engl J Med , vol.363 , pp. 2233-2247
    • Fahy, J.V.1    Dickey, B.F.2
  • 3
    • 0033823140 scopus 로고    scopus 로고
    • The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers
    • Sanders N.N., De Smedt S.C., Demeester J. The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers. J Pharm Sci 2000, 89:835-849.
    • (2000) J Pharm Sci , vol.89 , pp. 835-849
    • Sanders, N.N.1    De Smedt, S.C.2    Demeester, J.3
  • 4
    • 0034885192 scopus 로고    scopus 로고
    • The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition
    • Tarran R., Grubb B.R., Gatzy J.T., Davis C.W., Boucher R.C. The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition. J Gen Physiol 2001, 118:223-236.
    • (2001) J Gen Physiol , vol.118 , pp. 223-236
    • Tarran, R.1    Grubb, B.R.2    Gatzy, J.T.3    Davis, C.W.4    Boucher, R.C.5
  • 5
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
    • Lai S.K., Wang Y.Y., Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev 2009, 61:158-171.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 158-171
    • Lai, S.K.1    Wang, Y.Y.2    Hanes, J.3
  • 7
    • 60149110687 scopus 로고    scopus 로고
    • The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles
    • Suk J.S., Lai S.K., Wang Y.Y., Ensign L.M., Zeitlin P.L., Boyle M.P., et al. The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles. Biomaterials 2009, 30:2591-2597.
    • (2009) Biomaterials , vol.30 , pp. 2591-2597
    • Suk, J.S.1    Lai, S.K.2    Wang, Y.Y.3    Ensign, L.M.4    Zeitlin, P.L.5    Boyle, M.P.6
  • 9
    • 79959868168 scopus 로고    scopus 로고
    • Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus
    • Lai S.K., Suk J.S., Pace A., Wang Y.Y., Yang M., Mert O., et al. Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus. Biomaterials 2011, 32:6285-6290.
    • (2011) Biomaterials , vol.32 , pp. 6285-6290
    • Lai, S.K.1    Suk, J.S.2    Pace, A.3    Wang, Y.Y.4    Yang, M.5    Mert, O.6
  • 10
    • 60149089459 scopus 로고    scopus 로고
    • Barrier properties of mucus
    • Cone R.A. Barrier properties of mucus. Adv Drug Deliv Rev 2009, 61:75-85.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 75-85
    • Cone, R.A.1
  • 11
    • 2942692243 scopus 로고    scopus 로고
    • Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials
    • Valentine M.T., Perlman Z.E., Gardel M.L., Shin J.H., Matsudaira P., Mitchison T.J., et al. Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. Biophys J 2004, 86:4004-4014.
    • (2004) Biophys J , vol.86 , pp. 4004-4014
    • Valentine, M.T.1    Perlman, Z.E.2    Gardel, M.L.3    Shin, J.H.4    Matsudaira, P.5    Mitchison, T.J.6
  • 12
    • 76249115874 scopus 로고    scopus 로고
    • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
    • Lai S.K., Wang Y.Y., Hida K., Cone R., Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proc Natl Acad Sci U S A 2010, 107:598-603.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 598-603
    • Lai, S.K.1    Wang, Y.Y.2    Hida, K.3    Cone, R.4    Hanes, J.5
  • 13
    • 0025264393 scopus 로고
    • Collection and analysis of respiratory mucus from subjects without lung disease
    • Rubin B.K., Ramirez O., Zayas J.G., Finegan B., King M. Collection and analysis of respiratory mucus from subjects without lung disease. Am Rev Respir Dis 1990, 141:1040-1043.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 1040-1043
    • Rubin, B.K.1    Ramirez, O.2    Zayas, J.G.3    Finegan, B.4    King, M.5
  • 14
    • 0029152965 scopus 로고
    • Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects
    • Fahy J.V., Wong H., Liu J., Boushey H.A. Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med 1995, 152:53-58.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 53-58
    • Fahy, J.V.1    Wong, H.2    Liu, J.3    Boushey, H.A.4
  • 15
    • 0025294607 scopus 로고
    • General anesthesia does not alter the viscoelastic or transport properties of human respiratory mucus
    • Rubin B.K., Finegan B., Ramirez O., King M. General anesthesia does not alter the viscoelastic or transport properties of human respiratory mucus. Chest 1990, 98:101-104.
    • (1990) Chest , vol.98 , pp. 101-104
    • Rubin, B.K.1    Finegan, B.2    Ramirez, O.3    King, M.4
  • 16
    • 9644288111 scopus 로고    scopus 로고
    • Elastic contributions dominate the viscoelastic properties of sputum from cystic fibrosis patients
    • Nielsen H., Hvidt S., Sheils C.A., Janmey P.A. Elastic contributions dominate the viscoelastic properties of sputum from cystic fibrosis patients. Biophys Chem 2004, 112:193-200.
    • (2004) Biophys Chem , vol.112 , pp. 193-200
    • Nielsen, H.1    Hvidt, S.2    Sheils, C.A.3    Janmey, P.A.4
  • 18
    • 0023225795 scopus 로고
    • Fluorometric assay of O-linked glycoproteins by reaction with 2-cyanoacetamide
    • Crowther R.S., Wetmore R.F. Fluorometric assay of O-linked glycoproteins by reaction with 2-cyanoacetamide. Anal Biochem 1987, 163:170-174.
    • (1987) Anal Biochem , vol.163 , pp. 170-174
    • Crowther, R.S.1    Wetmore, R.F.2
  • 20
    • 84865820981 scopus 로고    scopus 로고
    • A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue
    • Nance E.A., Woodworth G.F., Sailor K.A., Shih T.Y., Xu Q., Swaminathan G., et al. A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue. Sci Transl Med 2012, 4:149ra19.
    • (2012) Sci Transl Med , vol.4
    • Nance, E.A.1    Woodworth, G.F.2    Sailor, K.A.3    Shih, T.Y.4    Xu, Q.5    Swaminathan, G.6
  • 21
    • 7044269314 scopus 로고    scopus 로고
    • Real-time multiple-particle tracking: applications to drug and gene delivery
    • Suh J., Dawson M., Hanes J. Real-time multiple-particle tracking: applications to drug and gene delivery. Adv Drug Deliv Rev 2005, 57:63-78.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 63-78
    • Suh, J.1    Dawson, M.2    Hanes, J.3
  • 22
    • 0030956033 scopus 로고    scopus 로고
    • Single-particle tracking: applications to membrane dynamics
    • Saxton M.J., Jacobson K. Single-particle tracking: applications to membrane dynamics. Annu Rev Biophys Biomol Struct 1997, 26:373-399.
    • (1997) Annu Rev Biophys Biomol Struct , vol.26 , pp. 373-399
    • Saxton, M.J.1    Jacobson, K.2
  • 23
    • 11944256524 scopus 로고
    • Optical measurements of frequency-dependent linear viscoelastic moduli of complex fluids
    • Mason T.G., Weitz D.A. Optical measurements of frequency-dependent linear viscoelastic moduli of complex fluids. Phys Rev Lett 1995, 74:1250-1253.
    • (1995) Phys Rev Lett , vol.74 , pp. 1250-1253
    • Mason, T.G.1    Weitz, D.A.2
  • 26
    • 0031817503 scopus 로고    scopus 로고
    • Sputum rheology changes in cystic fibrosis lung disease following two different types of physiotherapy: flutter vs autogenic drainage
    • App E.M., Kieselmann R., Reinhardt D., Lindemann H., Dasgupta B., King M., et al. Sputum rheology changes in cystic fibrosis lung disease following two different types of physiotherapy: flutter vs autogenic drainage. Chest 1998, 114:171-177.
    • (1998) Chest , vol.114 , pp. 171-177
    • App, E.M.1    Kieselmann, R.2    Reinhardt, D.3    Lindemann, H.4    Dasgupta, B.5    King, M.6
  • 27
    • 67749130687 scopus 로고    scopus 로고
    • Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma
    • Innes A.L., Carrington S.D., Thornton D.J., Kirkham S., Rousseau K., Dougherty R.H., et al. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med 2009, 180:203-210.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 203-210
    • Innes, A.L.1    Carrington, S.D.2    Thornton, D.J.3    Kirkham, S.4    Rousseau, K.5    Dougherty, R.H.6
  • 28
    • 79952598362 scopus 로고    scopus 로고
    • Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine
    • Suk J.S., Lai S.K., Boylan N.J., Dawson M.R., Boyle M.P., Hanes J. Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine. Nanomedicine (Lond) 2011, 6:365-375.
    • (2011) Nanomedicine (Lond) , vol.6 , pp. 365-375
    • Suk, J.S.1    Lai, S.K.2    Boylan, N.J.3    Dawson, M.R.4    Boyle, M.P.5    Hanes, J.6
  • 29
    • 0141530988 scopus 로고    scopus 로고
    • Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope
    • Braeckmans K., Peeters L., Sanders N.N., De Smedt S.C., Demeester J. Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope. Biophys J 2003, 85:2240-2252.
    • (2003) Biophys J , vol.85 , pp. 2240-2252
    • Braeckmans, K.1    Peeters, L.2    Sanders, N.N.3    De Smedt, S.C.4    Demeester, J.5
  • 30
    • 77953766334 scopus 로고    scopus 로고
    • Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
    • Garbuzenko O.B., Saad M., Pozharov V.P., Reuhl K.R., Mainelis G., Minko T. Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance. Proc Natl Acad Sci U S A 2010, 107:10737-10742.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10737-10742
    • Garbuzenko, O.B.1    Saad, M.2    Pozharov, V.P.3    Reuhl, K.R.4    Mainelis, G.5    Minko, T.6
  • 31
    • 80052339594 scopus 로고    scopus 로고
    • Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis
    • Ballester M., Nembrini C., Dhar N., de Titta A., de Piano C., Pasquier M., et al. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine 2011, 29:6959-6966.
    • (2011) Vaccine , vol.29 , pp. 6959-6966
    • Ballester, M.1    Nembrini, C.2    Dhar, N.3    de Titta, A.4    de Piano, C.5    Pasquier, M.6
  • 33
    • 84862519335 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus
    • Ensign L.M., Tang B.C., Wang Y.-Y., Tse T.A., Hoen T., Cone R., et al. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Sci Transl Med 2012, 4:138ra79.
    • (2012) Sci Transl Med , vol.4
    • Ensign, L.M.1    Tang, B.C.2    Wang, Y.-Y.3    Tse, T.A.4    Hoen, T.5    Cone, R.6
  • 35
    • 80053467043 scopus 로고    scopus 로고
    • Mobility of nonsticky nanoparticles in polymer liquids
    • Cai L.H., Panyukov S., Rubinstein M. Mobility of nonsticky nanoparticles in polymer liquids. Macromolecules 2011, 44:7853-7863.
    • (2011) Macromolecules , vol.44 , pp. 7853-7863
    • Cai, L.H.1    Panyukov, S.2    Rubinstein, M.3
  • 38
    • 0343510028 scopus 로고
    • Conformations of polymers attached to an interface
    • de Gennes P.G. Conformations of polymers attached to an interface. Macromolecules 1980, 13:1069-1075.
    • (1980) Macromolecules , vol.13 , pp. 1069-1075
    • de Gennes, P.G.1
  • 39
    • 84865278782 scopus 로고    scopus 로고
    • Biochemistry. Walking on solid ground
    • Dickey B.F. Biochemistry. Walking on solid ground. Science 2012, 337:924-925.
    • (2012) Science , vol.337 , pp. 924-925
    • Dickey, B.F.1
  • 40
    • 75549102827 scopus 로고
    • Studies on pulmonary secretions. I. The over-all chemical composition of pulmonary secretions from patients with cystic fibrosis, bronchiectasis, and laryngectomy
    • Matthews L.W., Spector S., Lemm J., Potter J.L. Studies on pulmonary secretions. I. The over-all chemical composition of pulmonary secretions from patients with cystic fibrosis, bronchiectasis, and laryngectomy. Am Rev Respir Dis 1963, 88:199-204.
    • (1963) Am Rev Respir Dis , vol.88 , pp. 199-204
    • Matthews, L.W.1    Spector, S.2    Lemm, J.3    Potter, J.L.4
  • 41
    • 59549095796 scopus 로고    scopus 로고
    • Altering mucus rheology to " solidify" human mucus at the nanoscale
    • Lai S.K., Wang Y.Y., Cone R., Wirtz D., Hanes J. Altering mucus rheology to " solidify" human mucus at the nanoscale. PLoS One 2009, 4:e4294.
    • (2009) PLoS One , vol.4
    • Lai, S.K.1    Wang, Y.Y.2    Cone, R.3    Wirtz, D.4    Hanes, J.5
  • 42
    • 3042707180 scopus 로고    scopus 로고
    • Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro
    • Shin J.H., Gardel M.L., Mahadevan L., Matsudaira P., Weitz D.A. Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro. Proc Natl Acad Sci U S A 2004, 101:9636-9641.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9636-9641
    • Shin, J.H.1    Gardel, M.L.2    Mahadevan, L.3    Matsudaira, P.4    Weitz, D.A.5
  • 44
    • 0029999804 scopus 로고    scopus 로고
    • Airway surfactant, a primary defense barrier: mechanical and immunological aspects
    • Gehr P., Green F.H., Geiser M., Im Hof V., Lee M.M., Schurch S. Airway surfactant, a primary defense barrier: mechanical and immunological aspects. J Aerosol Med 1996, 9:163-181.
    • (1996) J Aerosol Med , vol.9 , pp. 163-181
    • Gehr, P.1    Green, F.H.2    Geiser, M.3    Im Hof, V.4    Lee, M.M.5    Schurch, S.6
  • 45
    • 80455155066 scopus 로고    scopus 로고
    • N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles
    • Suk J.S., Boylan N.J., Trehan K., Tang B.C., Schneider C.S., Lin J.M., et al. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Mol Ther 2011, 19:1981-1989.
    • (2011) Mol Ther , vol.19 , pp. 1981-1989
    • Suk, J.S.1    Boylan, N.J.2    Trehan, K.3    Tang, B.C.4    Schneider, C.S.5    Lin, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.