Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 19, 2016, Pages 5382-5387

  Shah, Viral S ^a   Ernst, Sarah ^a   Tang, Xiao Xiao ^a   Karp, Philip H ^a   Parker, Connor P ^a   Ostedgaard, Lynda S ^a   Welsh, Michael J ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cystic fibrosis; Epithelia; Gene therapy; Host defense; Pig

Indexed keywords

AMILORIDE; BICARBONATE; CHLORIDE ION; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORSKOLIN; ISOBUTYLMETHYLXANTHINE;

ADENOVIRIDAE; AIRWAY; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL THERAPY; CONTROLLED STUDY; CYSTIC FIBROSIS; EPITHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENE TRANSFER; HETEROZYGOSITY; HOST RESISTANCE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; WILD TYPE; ANIMAL; GENE THERAPY; IMMUNOLOGY; INNATE IMMUNITY; NEWBORN; PIG; RESPIRATORY MUCOSA; STEM CELL TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; BICARBONATES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GENETIC THERAPY; IMMUNITY, INNATE; RESPIRATORY MUCOSA; STEM CELL TRANSPLANTATION; SWINE;

EID: 84966293252     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1604905113     Document Type: Article

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