Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 3, 2014, Pages 1076-1085

  Lehofer, Bernhard ^a,b   Bloder, Florian ^a   Jain, Pritesh P ^a   Marsh, Leigh M ^a   Leitinger, Gerd ^b   Olschewski, Horst ^a,b   Leber, Regina ^a,c   Olschewski, Andrea ^a   Prassl, Ruth ^a,b  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF GRAZ   (Austria)

Author keywords

Aerosol; Inhalation technique; Liposome; Nebulization; Pulmonary drug delivery; Vibrating mesh nebulizer

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,2 DIPALMITOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N [METHOXY(POLYETHYLENE GLYCOL) 2000]; ARTIFICIAL LUNG SURFACTANT; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; DRUG CARRIER; LIPOSOME; MACROGOL 2000; PHOSPHATIDYLCHOLINE; POLYMER; UNCLASSIFIED DRUG; AEROSOL;

AEROSOL; ARTICLE; CHEMICAL COMPOSITION; COMPARATIVE STUDY; CONTROLLED RELEASE FORMULATION; DRUG FORMULATION; DRUG RELEASE; DRUG RETENTION; DRUG STABILITY; DRUG TRANSPORT; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HYDRODYNAMICS; LIPID COMPOSITION; LIPID MEMBRANE; LIPOSOMAL DELIVERY; NEBULIZATION; NEBULIZER; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PHYSICAL CHEMISTRY; PRODUCTIVITY; REHYDRATION; SURFACE CHARGE; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; CHEMISTRY; MEDICINAL CHEMISTRY; METABOLISM; PHYSIOLOGY; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

AEROSOLS; BIOLOGICAL TRANSPORT; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; LIPOSOMES; NEBULIZERS AND VAPORIZERS; SURFACE PROPERTIES;

EID: 84912576210     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.10.009     Document Type: Article

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