Molecular mechanism of GPCR-mediated arrestin activation

Nature

Volumn 557, Issue 7705, 2018, Pages 452-456

  Latorraca, Naomi R ^a,b,c   Wang, Jason K ^b   Bauer, Brian ^d   Townshend, Raphael J L ^b   Hollingsworth, Scott A ^a,b,c   Olivieri, Julia E ^b   Xu, H Eric ^e,f   Sommer, Martha E ^d   Dror, Ron O ^a,b,c  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^f VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 1; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR; RETINA S ANTIGEN; RHODOPSIN; LIGAND;

CHEMICAL BINDING; CYTOPLASM; DRUG; FLUORESCENCE SPECTROSCOPY; MOLECULAR ANALYSIS; PROTEIN;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SPECTROFLUOROMETRY; ANIMAL; BOVINE; CHEMISTRY; METABOLISM; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME MECHANISM; LETTER; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIMULATION;

ANIMALS; ARRESTINS; CATTLE; LIGANDS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE;

EID: 85046889904     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-018-0077-3     Document Type: Article

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