Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 10, 2017, Pages 2562-2567

  Cahill, Thomas J ^a   Thomsen, Alex R B ^a   Tarrasch, Jeffrey T ^b,c   Plouffe, Bianca ^d   Nguyen, Anthony H ^a   Yang, Fan ^e   Huang, Li Yin ^a   Kahsai, Alem W ^a   Bassoni, Daniel L ^f   Gavino, Bryant J ^f   Lamerdin, Jane E ^f   Triest, Sarah ^g,h   Shukla, Arun K ^a,m   Berger, Benjamin ^a   Little, John ^a   Antar, Albert ^a   Blanc, Adi ^a   Qu, Chang Xiu ^e   Chen, Xin ⁱ   Kawakami, Kouki ^j   Inoue, Asuka ^j,k   Aoki, Junken ^j,l   Steyaert, Jan ^g,h   Sun, Jin Peng ^e   Bouvier, Michel ^d   Skiniotis, Georgios ^b,c   Lefkowitz, Robert J ^a   more..

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^e SHANDONG UNIVERSITY   (China)

^f DiscoveRx Corporation   (United States)

^g VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^h DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

ⁱ CHANGZHOU UNIVERSITY   (China)

^j TOHOKU UNIVERSITY   (Japan)

^k JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^l JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT   (Japan)

^m INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

more..

Author keywords

Arrestin; Desensitization; Endocytosis; GPCR; Signaling

Indexed keywords

BETA ARRESTIN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; MUTANT PROTEIN;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; BIOSENSOR; CELL MEMBRANE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CHEMISTRY; CONFORMATION; GENETICS;

AMINO ACID SEQUENCE; BETA-ARRESTINS; ENDOCYTOSIS; GTP-BINDING PROTEIN REGULATORS; HEK293 CELLS; HUMANS; MOLECULAR CONFORMATION; MULTIPROTEIN COMPLEXES; MUTANT PROTEINS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 85014696973     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1701529114     Document Type: Article

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