Cryo-EM structure of the gasdermin A3 membrane pore

Nature

Volumn 557, Issue 7703, 2018, Pages 62-67

  Ruan, Jianbin ^a,b   Xia, Shiyu ^a,b   Liu, Xing ^a,b   Lieberman, Judy ^a,b   Wu, Hao ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; GASDERMIN A3; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; GSDMA3 PROTEIN, MOUSE; GSDMD PROTEIN, HUMAN; MEMBRANE LIPID; MUTANT PROTEIN; PERFORIN; PROTEIN; TUMOR PROTEIN;

ENZYME; GENETIC ANALYSIS; LIPID; MEMBRANE; MICROSCOPY; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ENZYME INHIBITION; GOLD STANDARD; HUMAN; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL MEMBRANE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; MUTATION; NEOPLASM; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNIT; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ANIMALS; CELL MEMBRANE; CRYOELECTRON MICROSCOPY; HUMANS; MEMBRANE LIPIDS; MICE; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; NEOPLASM PROTEINS; NEOPLASMS; PERFORIN; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85046437366     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-018-0058-6     Document Type: Article

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