Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process

Nature Communications

Volumn 7, Issue , 2016, Pages

  Iacovache, Ioan ^a   De Carlo, Sacha ^b   Cirauqui, Nuria ^c,d   Dal Peraro, Matteo ^c,e   Van Der Goot, F Gisou ^c   Zuber, Benoît ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Thermo Fisher Scientific   (United States)

^c EPFL   (Switzerland)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AEROLYSIN; BACTERIAL TOXIN; PORE FORMING CYTOTOXIC PROTEIN;

APOPTOSIS; BIOCHEMISTRY; CHEMICAL ALTERATION; PATHOGEN; PHYSIOLOGICAL RESPONSE; PROTEIN; TOXIN;

ARTICLE; CHANNEL GATING; CONCENTRIC BETA BARREL FOLD; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; HYDROPHOBICITY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; STOICHIOMETRY; TOXIN ANALYSIS; TOXIN STRUCTURE; AEROMONAS HYDROPHILA; CHEMICAL PHENOMENA; IMAGE PROCESSING; MOLECULAR MODEL; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

AEROMONAS HYDROPHILA;

AEROMONAS HYDROPHILA; BACTERIAL TOXINS; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMAGE PROCESSING, COMPUTER-ASSISTED; MODELS, MOLECULAR; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84978828522     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12062     Document Type: Article

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