Deficiency of aldose reductase exacerbates early pressure overload-induced cardiac dysfunction and autophagy in mice

Journal of Molecular and Cellular Cardiology

Volumn 118, Issue , 2018, Pages 183-192

  Baba, Shahid P ^a   Zhang, Deqing ^a   Singh, Mahavir ^b   Dassanayaka, Sujith ^a   Xie, Zhengzhi ^a   Jagatheesan, Ganapathy ^a   Zhao, Jingjing ^a   Schmidtke, Virginia K ^a   Brittian, Kenneth R ^a   Merchant, Michael L ^b   Conklin, Daniel J ^a   Jones, Steven P ^a   Bhatnagar, Aruni ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Acrolein; Autophagy; Carnosine; Hydroxynonenal; Hypertrophy

Indexed keywords

3 HYDROXYPROPYLMERCAPTURIC ACID; ACETYLCYSTEINE; ACROLEIN; ADENYLATE KINASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALDEHYDE REDUCTASE; GREEN FLUORESCENT PROTEIN; MYOSIN; NATRIURETIC FACTOR; SEQUESTOSOME 1; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE; SQSTM1 PROTEIN, MOUSE; STRESS ACTIVATED PROTEIN KINASE;

ADULT; ANIMAL TISSUE; AORTIC CONSTRICTION; ARTICLE; AUTOPHAGY; BIOACCUMULATION; CARDIAC MUSCLE CELL; CARDIOVASCULAR PARAMETERS; DETOXIFICATION; DISEASE ASSOCIATION; DISEASE EXACERBATION; ENZYME PHOSPHORYLATION; GENE DELETION; HEART DISEASE; HEART EJECTION FRACTION; HEART FUNCTION; HEART HYPERTROPHY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; PRESSURE OVERLOAD; PRIORITY JOURNAL; PROTEIN EXPRESSION; URINE LEVEL; WILD TYPE; ANIMAL; AORTA; C57BL MOUSE; CARDIAC MUSCLE; CARDIOMEGALY; DEFICIENCY; DIAGNOSTIC IMAGING; ENZYMOLOGY; HEART; HEART CONTRACTION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PRESSURE; STENOSIS, OCCLUSION AND OBSTRUCTION;

ALDEHYDE REDUCTASE; ALDEHYDES; ANIMALS; AORTA; AUTOPHAGY; CARDIOMEGALY; CONSTRICTION, PATHOLOGIC; GENE DELETION; HEART; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE, INBRED C57BL; MYOCARDIAL CONTRACTION; MYOCARDIUM; PRESSURE; SEQUESTOSOME-1 PROTEIN;

EID: 85045187726     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2018.04.002     Document Type: Article

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