Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury

Circulation Research

Volumn 117, Issue 5, 2015, Pages 437-449

  Conklin, Daniel J ^a,b,c   Guo, Yiru ^b,c   Jagatheesan, Ganapathy ^a,c   Kilfoil, Peter J ^a,b,c,e   Haberzettl, Petra ^a,b,c   Hill, Bradford G ^a,b,c   Baba, Shahid P ^a,b,c   Guo, Luping ^a,c   Wetzelberger, Karin ^a   Obal, Detlef ^a,b,c,d   Gregg Rokosh, D ^a,b,c   Prough, Russell A ^e   Prabhu, Sumanth D ^f   Velayutham, Murugesan ^g   Zweier, Jay L ^g   David Hoetker, J ^a,c   Riggs, Daniel W ^a,c   Srivastava, Sanjay ^a,b,c   Bolli, Roberto ^a,b,c   Bhatnagar, Aruni ^a,b,c,e  

^a Diabetes and Obesity Center   (Germany)

^b Institute of Molecular Cardiology   (Germany)

^c Division of Cardiovascular Medicine   (Germany)

^d Department of Anesthesiology and Perioperative Medicine ^*  (Germany)

^e University of Louisville School of Medicine   (United States)

^f University of Alabama at Birmingham   (United States)

^g OHIO STATE UNIVERSITY   (United States)

Author keywords

acrolein; glutathione transferase; lipid peroxidation; myocardial infarction; myocardial ischemia; oxidative stress; reperfusion injury

Indexed keywords

ACROLEIN; ALDEHYDE; GLUTATHIONE TRANSFERASE P1; STRESS ACTIVATED PROTEIN KINASE; GLUTATHIONE TRANSFERASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORONARY ARTERY OCCLUSION; ELECTRON SPIN RESONANCE; HEART MUSCLE CELL; LIPID PEROXIDATION; MALE; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REPERFUSION INJURY; ANIMAL; C57BL MOUSE; DEFICIENCY; ENZYMOLOGY; GENETICS; HEART MUSCLE; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; GLUTATHIONE TRANSFERASE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM;

EID: 84939476034     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.114.305518     Document Type: Article

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