Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells

Toxicology and Applied Pharmacology

Volumn 227, Issue 2, 2008, Pages 257-264

  Yadav, Umesh C S ^a   Ramana, Kota V ^a   Awasthi, Yogesh C ^a   Srivastava, Satish K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aldose reductase; Comet assay; DNA damage; GSH; GST; HNE

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE REDUCTASE; BUTHIONINE SULFOXIMINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE A4; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; ERYTHROLEUKEMIA CELL; GENE OVEREXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; REGULATORY MECHANISM; SUPPLEMENTATION;

ALDEHYDE REDUCTASE; ALDEHYDES; COMET ASSAY; CYSTEINE PROTEINASE INHIBITORS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; K562 CELLS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MUTAGENS; OXIDATIVE STRESS; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION;

EID: 39149093682     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.10.025     Document Type: Article

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