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Volumn 33, Issue 4, 2018, Pages 676-689.e3

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

(729)  Taylor, Alison M a,b,c   Shih, Juliann b   Ha, Gavin a,b,c   Gao, Galen F b,g   Zhang, Xiaoyang a,b,c   Berger, Ashton C b   Schumacher, Steven E a,b   Wang, Chen d   Hu, Hai e   Liu, Jianfang e   Lazar, Alexander J f,g   Caesar Johnson, Samantha J g   Demchok, John A g   Felau, Ina g   Kasapi, Melpomeni g   Ferguson, Martin L g   Hutter, Carolyn M g   Sofia, Heidi J g   Tarnuzzer, Roy g   Wang, Zhining g   more..


Author keywords

aneuploidy; cancer genomics; genome engineering; lung squamous cell carcinoma

Indexed keywords

ANEUPLOIDY; ARTICLE; CELL PROLIFERATION; CHROMOSOME 3P; CHROMOSOME ARM; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CONTROLLED STUDY; GENETIC ENGINEERING; GENOME; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MALIGNANT NEOPLASM; PHENOTYPE; PRIORITY JOURNAL; CELL CYCLE; CHROMOSOME 3; CHROMOSOME ABERRATION; GENETIC DATABASE; GENETICS; GENOMICS; MUTATION RATE; PROCEDURES; SQUAMOUS CELL CARCINOMA;

EID: 85044906084     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2018.03.007     Document Type: Article
Times cited : (693)

References (55)
  • 2
    • 85034614124 scopus 로고    scopus 로고
    • xCell: digitally portraying the tissue cellular heterogeneity landscape
    • Aran, D., Hu, Z., Butte, A.J., xCell: digitally portraying the tissue cellular heterogeneity landscape. Genome Biol., 18, 2017, 220.
    • (2017) Genome Biol. , vol.18 , pp. 220
    • Aran, D.1    Hu, Z.2    Butte, A.J.3
  • 7
    • 84929492529 scopus 로고    scopus 로고
    • Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes
    • Bonney, M.E., Moriya, H., Amon, A., Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes. Genes Dev. 29 (2015), 898–903.
    • (2015) Genes Dev. , vol.29 , pp. 898-903
    • Bonney, M.E.1    Moriya, H.2    Amon, A.3
  • 9
    • 85017559196 scopus 로고    scopus 로고
    • Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation
    • Buccitelli, C., Salgueiro, L., Rowald, K., Sotillo, R., Mardin, B.R., Korbel, J.O., Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation. Genome Res. 27 (2017), 501–511.
    • (2017) Genome Res. , vol.27 , pp. 501-511
    • Buccitelli, C.1    Salgueiro, L.2    Rowald, K.3    Sotillo, R.4    Mardin, B.R.5    Korbel, J.O.6
  • 16
    • 33748286796 scopus 로고    scopus 로고
    • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
    • Carter, S.L., Eklund, A.C., Kohane, I.S., Harris, L.N., Szallasi, Z., A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat. Genet. 38 (2006), 1043–1048.
    • (2006) Nat. Genet. , vol.38 , pp. 1043-1048
    • Carter, S.L.1    Eklund, A.C.2    Kohane, I.S.3    Harris, L.N.4    Szallasi, Z.5
  • 18
    • 85010652953 scopus 로고    scopus 로고
    • Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
    • Davoli, T., Uno, H., Wooten, E.C., Elledge, S.J., Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy. Science, 355, 2017, 10.1126/science.aaf8399.
    • (2017) Science , vol.355
    • Davoli, T.1    Uno, H.2    Wooten, E.C.3    Elledge, S.J.4
  • 23
    • 67649522162 scopus 로고    scopus 로고
    • Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
    • Holland, A.J., Cleveland, D.W., Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat. Rev. Mol. Cell Biol. 10 (2009), 478–487.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 478-487
    • Holland, A.J.1    Cleveland, D.W.2
  • 25
    • 0029653451 scopus 로고
    • Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma
    • Hung, J., Kishimoto, Y., Sugio, K., Virmani, A., McIntire, D.D., Minna, J.D., Gazdar, A.F., Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma. JAMA 273 (1995), 558–563.
    • (1995) JAMA , vol.273 , pp. 558-563
    • Hung, J.1    Kishimoto, Y.2    Sugio, K.3    Virmani, A.4    McIntire, D.D.5    Minna, J.D.6    Gazdar, A.F.7
  • 26
    • 85029390412 scopus 로고    scopus 로고
    • HMMcopy: Copy Number Prediction with Correction for GC and Mappability Bias for HTS Data. R Package Version 1.18.0
    • Lai, D., Ha, G., Shah, S., HMMcopy: Copy Number Prediction with Correction for GC and Mappability Bias for HTS Data. R Package Version 1.18.0. 2016 https://rdrr.io/bioc/HMMcopy/.
    • (2016)
    • Lai, D.1    Ha, G.2    Shah, S.3
  • 27
    • 82755186408 scopus 로고    scopus 로고
    • Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence
    • Larsson, L.G., Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence. Semin. Cancer Biol. 21 (2011), 367–376.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 367-376
    • Larsson, L.G.1
  • 28
    • 79961123152 scopus 로고    scopus 로고
    • RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
    • Li, B., Dewey, C.N., RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics, 12, 2011, 323.
    • (2011) BMC Bioinformatics , vol.12 , pp. 323
    • Li, B.1    Dewey, C.N.2
  • 31
    • 84884856342 scopus 로고    scopus 로고
    • Cas9 as a versatile tool for engineering biology
    • Mali, P., Esvelt, K.M., Church, G.M., Cas9 as a versatile tool for engineering biology. Nat. Methods 10 (2013), 957–963.
    • (2013) Nat. Methods , vol.10 , pp. 957-963
    • Mali, P.1    Esvelt, K.M.2    Church, G.M.3
  • 32
    • 0034125650 scopus 로고    scopus 로고
    • Recurrent chromosome aberrations in cancer
    • Mitelman, F., Recurrent chromosome aberrations in cancer. Mutat. Res. 462 (2000), 247–253.
    • (2000) Mutat. Res. , vol.462 , pp. 247-253
    • Mitelman, F.1
  • 36
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M.D., McCarthy, D.J., Smyth, G.K., edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26 (2010), 139–140.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 37
    • 85030443697 scopus 로고    scopus 로고
    • Chromosome mis-segregation generates cell-cycle-arrested cells with complex karyotypes that are eliminated by the immune system
    • Santaguida, S., Richardson, A., Iyer, D.R., M'Saad, O., Zasadil, L., Knouse, K.A., Wong, Y.L., Rhind, N., Desai, A., Amon, A., Chromosome mis-segregation generates cell-cycle-arrested cells with complex karyotypes that are eliminated by the immune system. Dev. Cell 41 (2017), 638–651.e5.
    • (2017) Dev. Cell , vol.41 , pp. 638-651.e5
    • Santaguida, S.1    Richardson, A.2    Iyer, D.R.3    M'Saad, O.4    Zasadil, L.5    Knouse, K.A.6    Wong, Y.L.7    Rhind, N.8    Desai, A.9    Amon, A.10
  • 41
    • 84868290476 scopus 로고    scopus 로고
    • Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
    • Stingele, S., Stoehr, G., Peplowska, K., Cox, J., Mann, M., Storchova, Z., Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Mol. Syst. Biol., 8, 2012, 608.
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 608
    • Stingele, S.1    Stoehr, G.2    Peplowska, K.3    Cox, J.4    Mann, M.5    Storchova, Z.6
  • 43
    • 11944271246 scopus 로고
    • p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus
    • Sundaresan, V., Ganly, P., Hasleton, P., Rudd, R., Sinha, G., Bleehen, N.M., Rabbitts, P., p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus. Oncogene 7 (1992), 1989–1997.
    • (1992) Oncogene , vol.7 , pp. 1989-1997
    • Sundaresan, V.1    Ganly, P.2    Hasleton, P.3    Rudd, R.4    Sinha, G.5    Bleehen, N.M.6    Rabbitts, P.7
  • 44
    • 84873314664 scopus 로고    scopus 로고
    • Gene copy-number alterations: a cost-benefit analysis
    • Tang, Y.C., Amon, A., Gene copy-number alterations: a cost-benefit analysis. Cell 152 (2013), 394–405.
    • (2013) Cell , vol.152 , pp. 394-405
    • Tang, Y.C.1    Amon, A.2
  • 47
    • 84963621254 scopus 로고    scopus 로고
    • Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
    • Topalian, S.L., Taube, J.M., Anders, R.A., Pardoll, D.M., Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy. Nat. Rev. Cancer 16 (2016), 275–287.
    • (2016) Nat. Rev. Cancer , vol.16 , pp. 275-287
    • Topalian, S.L.1    Taube, J.M.2    Anders, R.A.3    Pardoll, D.M.4
  • 48
  • 49
    • 85030760821 scopus 로고    scopus 로고
    • CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells
    • Uno, N., Hiramatsu, K., Uno, K., Komoto, S., Kazuki, Y., Oshimura, M., CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells. Sci. Rep., 7, 2017, 12739.
    • (2017) Sci. Rep. , vol.7 , pp. 12739
    • Uno, N.1    Hiramatsu, K.2    Uno, K.3    Komoto, S.4    Kazuki, Y.5    Oshimura, M.6
  • 52
    • 19244370711 scopus 로고    scopus 로고
    • High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
    • Wistuba, I.I., Behrens, C., Virmani, A.K., Mele, G., Milchgrub, S., Girard, L., Fondon, J.W. 3rd, Garner, H.R., McKay, B., Latif, F., et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res. 60 (2000), 1949–1960.
    • (2000) Cancer Res. , vol.60 , pp. 1949-1960
    • Wistuba, I.I.1    Behrens, C.2    Virmani, A.K.3    Mele, G.4    Milchgrub, S.5    Girard, L.6    Fondon, J.W.7    Garner, H.R.8    McKay, B.9    Latif, F.10
  • 54
    • 0037037787 scopus 로고    scopus 로고
    • Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
    • Zabarovsky, E.R., Lerman, M.I., Minna, J.D., Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene 21 (2002), 6915–6935.
    • (2002) Oncogene , vol.21 , pp. 6915-6935
    • Zabarovsky, E.R.1    Lerman, M.I.2    Minna, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.