-
1
-
-
67649506317
-
Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
-
Baek K-H, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park I-H, Yoon SS, Minami T, et al. 2009. Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 459: 1126–1130.
-
(2009)
Nature
, vol.459
, pp. 1126-1130
-
-
Baek, K.-H.1
Zaslavsky, A.2
Lynch, R.C.3
Britt, C.4
Okada, Y.5
Siarey, R.J.6
Lensch, M.W.7
Park, I.-H.8
Yoon, S.S.9
Minami, T.10
-
2
-
-
84928138338
-
Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast
-
Blank HM, Sheltzer JM, Meehl CM, Amon A. 2015. Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast. Mol Biol Cell doi: 10.1091/mbc.E14-10-1442.
-
(2015)
Mol Biol Cell
-
-
Blank, H.M.1
Sheltzer, J.M.2
Meehl, C.M.3
Amon, A.4
-
3
-
-
21644469000
-
Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae
-
Boyer J, Badis G, Fairhead C, Talla E, Hantraye F, Fabre E, Fischer G, Hennequin C, Koszul R, Lafontaine I, et al. 2004. Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae. Genome Biol 5: R72.
-
(2004)
Genome Biol
, vol.5
, pp. R72
-
-
Boyer, J.1
Badis, G.2
Fairhead, C.3
Talla, E.4
Hantraye, F.5
Fabre, E.6
Fischer, G.7
Hennequin, C.8
Koszul, R.9
Lafontaine, I.10
-
4
-
-
84922718815
-
Targeting the adaptability of heterogeneous aneuploids
-
Chen G, Mulla WA, Kucharavy A, Tsai H-J, Rubinstein B, Conkright J, McCroskey S, Bradford WD, Weems L, Haug JS, et al. 2015. Targeting the adaptability of heterogeneous aneuploids. Cell 160: 771–784.
-
(2015)
Cell
, vol.160
, pp. 771-784
-
-
Chen, G.1
Mulla, W.A.2
Kucharavy, A.3
Tsai, H.-J.4
Rubinstein, B.5
Conkright, J.6
McCroskey, S.7
Bradford, W.D.8
Weems, L.9
Haug, J.S.10
-
5
-
-
54549102143
-
Identification of human haploinsufficient genes and their genomic proximity to segmental duplications
-
Dang VT, Kassahn KS, Marcos AE, Ragan MA. 2008. Identification of human haploinsufficient genes and their genomic proximity to segmental duplications. Eur J Hum Genet 16: 1350–1357.
-
(2008)
Eur J Hum Genet
, vol.16
, pp. 1350-1357
-
-
Dang, V.T.1
Kassahn, K.S.2
Marcos, A.E.3
Ragan, M.A.4
-
6
-
-
84883146045
-
Functional analysis with a barcoder yeast gene overexpression system
-
Douglas AC, Smith AM, Sharifpoor S, Yan Z, Durbic T, Heisler LE, Lee AY, Ryan O, Göttert H, Surendra A, et al. 2012. Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) 2: 1279–1289.
-
(2012)
G3 (Bethesda)
, vol.2
, pp. 1279-1289
-
-
Douglas, A.C.1
Smith, A.M.2
Sharifpoor, S.3
Yan, Z.4
Durbic, T.5
Heisler, L.E.6
Lee, A.Y.7
Ryan, O.8
Göttert, H.9
Surendra, A.10
-
7
-
-
0022727854
-
Toxic effects of excess cloned centromeres
-
Futcher B, Carbon J. 1986. Toxic effects of excess cloned centromeres. Mol Cell Biol 6: 2213–2222.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2213-2222
-
-
Futcher, B.1
Carbon, J.2
-
8
-
-
28444478789
-
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection
-
Gelperin DM, White MA, Wilkinson ML, Kon Y, Kung LA, Wise KJ, Lopez- Hoyo N, Jiang L, Piccirillo S, Yu H, et al. 2005. Biochemical and genetic analysis of the yeast proteome with a movable ORF collection. Genes Dev 19: 2816–2826.
-
(2005)
Genes Dev
, vol.19
, pp. 2816-2826
-
-
Gelperin, D.M.1
White, M.A.2
Wilkinson, M.L.3
Kon, Y.4
Kung, L.A.5
Wise, K.J.6
Lopez- Hoyo, N.7
Jiang, L.8
Piccirillo, S.9
Yu, H.10
-
9
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson DG, Young L, Chuang R-Y, Venter JC, Hutchison CA, Smith HO. 2009. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Methods 6: 343–345.
-
(2009)
Nat Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.-Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
11
-
-
64349112353
-
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds
-
Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JLY, Porter J, Gray CA, Andersen RJ, et al. 2009. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds. Nat Biotechnol 27: 369–377.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 369-377
-
-
Ho, C.H.1
Magtanong, L.2
Barker, S.L.3
Gresham, D.4
Nishimura, S.5
Natarajan, P.6
Koh, J.7
Porter, J.8
Gray, C.A.9
Ersen, R.J.10
-
12
-
-
78449263023
-
Characterising and predicting haploinsufficiency in the human genome
-
Huang N, Lee I, Marcotte EM, Hurles ME. 2010. Characterising and predicting haploinsufficiency in the human genome. PLoS Genet 6: e1001154.
-
(2010)
Plos Genet
, pp. 6
-
-
Huang, N.1
Lee, I.2
Marcotte, E.M.3
Hurles, M.E.4
-
13
-
-
0025063865
-
Regulation of tubulin levels and microtubule assembly in Saccharomyces cerevisiae: Consequences of altered tubulin gene copy number
-
Katz W, Weinstein B, Solomon F. 1990. Regulation of tubulin levels and microtubule assembly in Saccharomyces cerevisiae: consequences of altered tubulin gene copy number. Mol Cell Biol 10: 5286–5294.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 5286-5294
-
-
Katz, W.1
Weinstein, B.2
Solomon, F.3
-
14
-
-
0021369651
-
Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces
-
Kilmartin JV, Adams AE. 1984. Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol 98: 922–933.
-
(1984)
J Cell Biol
, vol.98
, pp. 922-933
-
-
Kilmartin, J.V.1
Adams, A.E.2
-
15
-
-
67749148222
-
The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies
-
Korbel JO, Tirosh-Wagner T, Urban AE, Chen X-N, Kasowski M, Dai L, Grubert F, Erdman C, Gao MC, Lange K, et al. 2009. The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies. Proc Natl Acad Sci 106: 12031–12036.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 12031-12036
-
-
Korbel, J.O.1
Tirosh-Wagner, T.2
Urban, A.E.3
Chen, X.-N.4
Kasowski, M.5
Dai, L.6
Grubert, F.7
Erdman, C.8
Gao, M.C.9
Lange, K.10
-
16
-
-
0015344332
-
Segmental aneuploidy and the genetic gross structure of the Drosophila genome
-
Lindsley DL, Sandler L, Baker BS, Carpenter AT, Denell RE, Hall JC, Jacobs PA, Miklos GL, Davis BK, Gethmann RC, et al. 1972. Segmental aneuploidy and the genetic gross structure of the Drosophila genome. Genetics 71: 157–184.
-
(1972)
Genetics
, vol.71
, pp. 157-184
-
-
Lindsley, D.L.1
Sandler, L.2
Baker, B.S.3
Carpenter, A.T.4
Denell, R.E.5
Hall, J.C.6
Jacobs, P.A.7
Miklos, G.L.8
Davis, B.K.9
Gethmann, R.C.10
-
17
-
-
0026737743
-
Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast
-
Liu H, Krizek J, Bretscher A. 1992. Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast. Genetics 132: 665–673.
-
(1992)
Genetics
, vol.132
, pp. 665-673
-
-
Liu, H.1
Krizek, J.2
Bretscher, A.3
-
18
-
-
84873345436
-
Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method
-
Makanae K, Kintaka R, Makino T, Kitano H, Moriya H. 2013. Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method. Genome Res 23: 300–311.
-
(2013)
Genome Res
, vol.23
, pp. 300-311
-
-
Makanae, K.1
Kintaka, R.2
Makino, T.3
Kitano, H.4
Moriya, H.5
-
19
-
-
84865787237
-
Robustness analysis of cellular systems using the genetic tug-of-war method
-
Moriya H, Makanae K, Watanabe K, Chino A, Shimizu-Yoshida Y. 2012. Robustness analysis of cellular systems using the genetic tug-of-war method. Mol Biosyst 8: 2513–2522.
-
(2012)
Mol Biosyst
, vol.8
, pp. 2513-2522
-
-
Moriya, H.1
Makanae, K.2
Watanabe, K.3
Chino, A.4
Shimizu-Yoshida, Y.5
-
20
-
-
0035049593
-
Overexpression of translation elongation factor 1A affects the organization and function of the actin cytoskeleton in yeast
-
Munshi R, Kandl KA, Carr-Schmid A, Whitacre JL, Adams AE, Kinzy TG. 2001. Overexpression of translation elongation factor 1A affects the organization and function of the actin cytoskeleton in yeast. Genetics 157: 1425–1436.
-
(2001)
Genetics
, vol.157
, pp. 1425-1436
-
-
Munshi, R.1
Kandl, K.A.2
Carr-Schmid, A.3
Whitacre, J.L.4
Adams, A.E.5
Kinzy, T.G.6
-
21
-
-
0020600632
-
Isolation of the β-tubulin gene from yeast and demonstration of its essential function in vivo
-
Neff NF, Thomas JH, Grisafi P, Botstein D. 1983. Isolation of the β-tubulin gene from yeast and demonstration of its essential function in vivo. Cell 33: 211–219.
-
(1983)
Cell
, vol.33
, pp. 211-219
-
-
Neff, N.F.1
Thomas, J.H.2
Grisafi, P.3
Botstein, D.4
-
22
-
-
7444231620
-
A chromosome 21 critical region does not cause specific Down syndrome phenotypes
-
Olson LE, Richtsmeier JT, Leszl J, Reeves RH. 2004a. A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science 306: 687–690.
-
(2004)
Science
, vol.306
, pp. 687-690
-
-
Olson, L.E.1
Richtsmeier, J.T.2
Leszl, J.3
Reeves, R.H.4
-
23
-
-
3042612213
-
Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
-
Olson LE, Roper RJ, Baxter LL, Carlson EJ, Epstein CJ, Reeves RH. 2004b. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Dev Dyn 230: 581–589.
-
(2004)
Dev Dyn
, vol.230
, pp. 581-589
-
-
Olson, L.E.1
Roper, R.J.2
Baxter, L.L.3
Carlson, E.J.4
Epstein, C.J.5
Reeves, R.H.6
-
24
-
-
34447338354
-
Trisomy for the Down syndrome ‘critical region’ is necessary but not sufficient for brain phenotypes of trisomic mice
-
Olson LE, Roper RJ, Sengstaken CL, Peterson EA, Aquino V, Galdzicki Z, Siarey R, Pletnikov M, Moran TH, Reeves RH. 2007. Trisomy for the Down syndrome ‘critical region’ is necessary but not sufficient for brain phenotypes of trisomic mice. Hum Mol Genet 16: 774–782.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 774-782
-
-
Olson, L.E.1
Roper, R.J.2
Sengstaken, C.L.3
Peterson, E.A.4
Aquino, V.5
Galdzicki, Z.6
Siarey, R.7
Pletnikov, M.8
Moran, T.H.9
Reeves, R.H.10
-
25
-
-
35548991458
-
Mental retardation in Down syndrome: From gene dosage imbalance to molecular and cellular mechanisms
-
Rachidi M, Lopes C. 2007. Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms. Neurosci Res 59: 349–369.
-
(2007)
Neurosci Res
, vol.59
, pp. 349-369
-
-
Rachidi, M.1
Lopes, C.2
-
26
-
-
0025654656
-
Down syndrome critical region around D21S55 on proximal 21q22.3
-
Rahmani Z, Blouin JL, Créau-Goldberg N, Watkins PC, Mattei JF, Poissonnier M, Prieur M, Chettouh Z, Nicole A, Aurias A. 1990. Down syndrome critical region around D21S55 on proximal 21q22.3. Am J Med Genet 7: 98–103.
-
(1990)
Am J Med Genet
, vol.7
, pp. 98-103
-
-
Rahmani, Z.1
Blouin, J.L.2
Créau-Goldberg, N.3
Watkins, P.C.4
Mattei, J.F.5
Poissonnier, M.6
Prieur, M.7
Chettouh, Z.8
Nicole, A.9
Aurias, A.10
-
27
-
-
29444442794
-
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
-
Rovelet-Lecrux A, Hannequin D, Raux G, Le Meur N, Laquerrière A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M, et al. 2006. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38: 24–26.
-
(2006)
Nat Genet
, vol.38
, pp. 24-26
-
-
Rovelet-Lecrux, A.1
Hannequin, D.2
Raux, G.3
Le Meur, N.4
Laquerrière, A.5
Vital, A.6
Dumanchin, C.7
Feuillette, S.8
Brice, A.9
Vercelletto, M.10
-
28
-
-
0024342769
-
Amyloid A4 protein and its precursor in Down’s syndrome and Alzheimer’s disease
-
Rumble B, Retallack R, Hilbich C, Simms G, Multhaup G, Martins R, Hockey A, Montgomery P, Beyreuther K, Masters CL. 1989. Amyloid A4 protein and its precursor in Down’s syndrome and Alzheimer’s disease. N Engl J Med 320: 1446–1452.
-
(1989)
N Engl J Med
, vol.320
, pp. 1446-1452
-
-
Rumble, B.1
Retallack, R.2
Hilbich, C.3
Simms, G.4
Multhaup, G.5
Martins, R.6
Hockey, A.7
Montgomery, P.8
Beyreuther, K.9
Masters, C.L.10
-
29
-
-
31544482407
-
Mapping pathways and phenotypes by systematic gene overexpression
-
Sopko R, Huang D, Preston N, Chua G, Papp B, Kafadar K, Snyder M, Oliver SG, Cyert M, Hughes TR, et al. 2006. Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21: 319–330.
-
(2006)
Mol Cell
, vol.21
, pp. 319-330
-
-
Sopko, R.1
Huang, D.2
Preston, N.3
Chua, G.4
Papp, B.5
Kafadar, K.6
Snyder, M.7
Oliver, S.G.8
Cyert, M.9
Hughes, T.R.10
-
30
-
-
33646886350
-
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease
-
Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, De Pooter T, van Duijn CM, De Deyn PP, Van Broeckhoven C. 2006. Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease. Am J Hum Genet 78: 936–946.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 936-946
-
-
Theuns, J.1
Brouwers, N.2
Engelborghs, S.3
Sleegers, K.4
Bogaerts, V.5
Corsmit, E.6
De Pooter, T.7
Van Duijn, C.M.8
De Deyn, P.P.9
Van Broeckhoven, C.10
-
31
-
-
84877108757
-
Aneuploid yeast strains exhibit defects in cell growth and passage through START
-
Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. 2013. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Mol Biol Cell 24: 1274–1289.
-
(2013)
Mol Biol Cell
, vol.24
, pp. 1274-1289
-
-
Thorburn, R.R.1
Gonzalez, C.2
Brar, G.A.3
Christen, S.4
Carlile, T.M.5
Ingolia, N.T.6
Sauer, U.7
Weissman, J.S.8
Amon, A.9
-
32
-
-
34548131710
-
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
-
Torres EM, Sokolsky T, Tucker CM, Chan LY, Boselli M, Dunham MJ, Amon A. 2007. Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science 317: 916–924.
-
(2007)
Science
, vol.317
, pp. 916-924
-
-
Torres, E.M.1
Sokolsky, T.2
Tucker, C.M.3
Chan, L.Y.4
Boselli, M.5
Dunham, M.J.6
Amon, A.7
-
33
-
-
49849103726
-
Aneuploidy: Cells losing their balance
-
Torres EM, Williams BR, Amon A. 2008. Aneuploidy: cells losing their balance. Genetics 179: 737–746.
-
(2008)
Genetics
, vol.179
, pp. 737-746
-
-
Torres, E.M.1
Williams, B.R.2
Amon, A.3
|