Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

Cell Systems

Volumn 6, Issue 3, 2018, Pages 271-281.e7

  Ellrott, Kyle ^a   Bailey, Matthew H ^b,j   Saksena, Gordon ^c,j   Covington, Kyle R ^d,j   Kandoth, Cyriac ^e,j   Stewart, Chip ^c   Hess, Julian ^c,j   Ma, Singer ^g   Chiotti, Kami E ^a   McLellan, Michael D ^b,j   Sofia, Heidi J ^f,j   Hutter, Carolyn M ^f,j   Getz, Gad ^c,h,i,j   Wheeler, David A ^d,j   Ding, Li ^b,j   Caesar Johnson, Samantha J ^j   Demchok, John A ^j   Felau, Ina ^j   Kasapi, Melpomeni ^j   Ferguson, Martin L ^j   Tarnuzzer, Roy ^j   Wang, Zhining ^j   Yang, Liming ^j   Zenklusen, Jean C ^j   more..

^a Oregon Health and Science University Department of Biomedical Engineering   (United States)

^b Washington University in St Louis School of Medicine   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^g DNAnexus   (United States)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j Julia)

more..

Author keywords

large scale; open science; pan cancer; PanCanAtlas project; reproducible computing; somatic mutation calling; TCGA

Indexed keywords

ARTICLE; CANCER GENETICS; DNA EXTRACTION; DNA HYBRIDIZATION; DNA SEQUENCE; EXOME; GENE MUTATION; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; ALGORITHM; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; INFORMATION DISSEMINATION; MUTATION; NEOPLASM; PROCEDURES; SOFTWARE; WHOLE EXOME SEQUENCING;

ALGORITHMS; EXOME; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFORMATION DISSEMINATION; MUTATION; NEOPLASMS; SEQUENCE ANALYSIS, DNA; SOFTWARE; WHOLE EXOME SEQUENCING;

EID: 85044569292     PISSN: 24054712     EISSN: 24054720     Source Type: Journal    
DOI: 10.1016/j.cels.2018.03.002     Document Type: Article

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