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Volumn 144, Issue 6, 2017, Pages 986-997

Lung organoids: Current uses and future promise

Author keywords

Lung organoids; Lung progenitors; Plasticity; Stem cells

Indexed keywords

AIRWAY CELL; ASTHMA; BASAL CELL; CELL ISOLATION; CELL PLASTICITY; CELL STRUCTURE; CYSTIC FIBROSIS; CYTOPLASM; HUMAN; INDUCED PLURIPOTENT STEM CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS CELL TYPE 2; NONHUMAN; PRIORITY JOURNAL; REVIEW; SECRETORY CELL; STEM CELL; ANIMAL; CYTOLOGY; LUNG; LUNG ALVEOLUS EPITHELIUM CELL;

EID: 85015309695     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.140103     Document Type: Review
Times cited : (305)

References (64)
  • 6
    • 84975275212 scopus 로고    scopus 로고
    • Modeling development and disease with organoids
    • Clevers, H. (2016). Modeling development and disease with organoids. Cell 165, 1586-1597.
    • (2016) Cell , vol.165 , pp. 1586-1597
    • Clevers, H.1
  • 8
    • 84896319764 scopus 로고    scopus 로고
    • Alveolar progenitor and stem cells in lung development, renewal and cancer
    • Desai, T. J., Brownfield, D. G. and Krasnow, M. A. (2014). Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature 507, 190-194.
    • (2014) Nature , vol.507 , pp. 190-194
    • Desai, T.J.1    Brownfield, D.G.2    Krasnow, M.A.3
  • 10
    • 84994584920 scopus 로고    scopus 로고
    • A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids
    • Dye, B. R., Dedhia, P. H., Miller, A. J., Nagy, M. S., White, E. S., Shea, L. D. and Spence, J. R. (2016). A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids. Elife 5, e19732.
    • (2016) Elife , vol.5
    • Dye, B.R.1    Dedhia, P.H.2    Miller, A.J.3    Nagy, M.S.4    White, E.S.5    Shea, L.D.6    Spence, J.R.7
  • 11
    • 0014579366 scopus 로고
    • Identification of cells labeled with tritiated thymidine in the pulmonary alveolar walls of the mouse
    • Evans, M. J. and Bils, R. F. (1969). Identification of cells labeled with tritiated thymidine in the pulmonary alveolar walls of the mouse. Am. Rev. Respir. Dis. 100, 372-378.
    • (1969) Am. Rev. Respir. Dis , vol.100 , pp. 372-378
    • Evans, M.J.1    Bils, R.F.2
  • 12
    • 0015581422 scopus 로고
    • Renewal of alveolar epithelium in the rat following exposure to NO2
    • Evans, M. J., Cabral, L. J., Stephens, R. J. and Freeman, G. (1973). Renewal of alveolar epithelium in the rat following exposure to NO2. Am. J. Pathol. 70, 175-198.
    • (1973) Am. J. Pathol , vol.70 , pp. 175-198
    • Evans, M.J.1    Cabral, L.J.2    Stephens, R.J.3    Freeman, G.4
  • 15
    • 84980343841 scopus 로고    scopus 로고
    • GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells
    • Gao, X., Bali, A. S., Randell, S. H. and Hogan, B. L. M. (2015). GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J. Cell Biol. 211, 669-682.
    • (2015) J. Cell Biol , vol.211 , pp. 669-682
    • Gao, X.1    Bali, A.S.2    Randell, S.H.3    Hogan, B.L.M.4
  • 18
    • 0036314791 scopus 로고    scopus 로고
    • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
    • Giangreco, A., Reynolds, S. D. and Stripp, B. R. (2002). Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am. J. Pathol. 161, 173-182.
    • (2002) Am. J. Pathol , vol.161 , pp. 173-182
    • Giangreco, A.1    Reynolds, S.D.2    Stripp, B.R.3
  • 19
    • 77957319700 scopus 로고    scopus 로고
    • HTII-280, a biomarker specific to the apical plasma membrane of human lung alveolar type II cells
    • Gonzalez, R. F., Allen, L., Gonzales, L., Ballard, P. L. and Dobbs, L. G. (2010). HTII-280, a biomarker specific to the apical plasma membrane of human lung alveolar type II cells. J. Histochem. Cytochem. 58, 891-901.
    • (2010) J. Histochem. Cytochem , vol.58 , pp. 891-901
    • Gonzalez, R.F.1    Allen, L.2    Gonzales, L.3    Ballard, P.L.4    Dobbs, L.G.5
  • 23
    • 85026637661 scopus 로고    scopus 로고
    • Production of 3-D airway organoids from primary human airway basal cells and their use in high-throughput screening
    • Hild, M. and Jaffe, A. B. (2016). Production of 3-D airway organoids from primary human airway basal cells and their use in high-throughput screening. Curr. Protoc. Stem Cell Biol. 37, IE 9 1-IE 9 15.
    • (2016) Curr. Protoc. Stem Cell Biol , vol.37
    • Hild, M.1    Jaffe, A.B.2
  • 25
    • 1642269178 scopus 로고    scopus 로고
    • In vivo differentiation potential of tracheal basal cells: Evidence for multipotent and unipotent subpopulations
    • Hong, K. U., Reynolds, S. D., Watkins, S., Fuchs, E. and Stripp, B. R. (2004). In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am. J. Physiol. Lung Cell. Mol. Physiol. 286, L643-L649.
    • (2004) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.286 , pp. L643-L649
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3    Fuchs, E.4    Stripp, B.R.5
  • 30
    • 80155148257 scopus 로고    scopus 로고
    • Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection
    • Kumar, P. A., Hu, Y., Yamamoto, Y., Hoe, N. B., Wei, T. S., Mu, D., Sun, Y., Joo, L. S., Dagher, R., Zielonka, E. M. et al. (2011). Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 147, 525-538.
    • (2011) Cell , vol.147 , pp. 525-538
    • Kumar, P.A.1    Hu, Y.2    Yamamoto, Y.3    Hoe, N.B.4    Wei, T.S.5    Mu, D.6    Sun, Y.7    Joo, L.S.8    Dagher, R.9    Zielonka, E.M.10
  • 34
    • 76549126430 scopus 로고    scopus 로고
    • Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung
    • McQualter, J. L., Yuen, K., Williams, B. and Bertoncello, I. (2010). Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung. Proc. Natl. Acad. Sci. USA 107, 1414-1419.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 1414-1419
    • McQualter, J.L.1    Yuen, K.2    Williams, B.3    Bertoncello, I.4
  • 35
  • 36
    • 74049139927 scopus 로고    scopus 로고
    • Preparing for the first breath: Genetic and cellular mechanisms in lung development
    • Morrisey, E. E. and Hogan, B. L. M. (2010). Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev. Cell 18, 8-23.
    • (2010) Dev. Cell , vol.18 , pp. 8-23
    • Morrisey, E.E.1    Hogan, B.L.M.2
  • 39
    • 84871254312 scopus 로고    scopus 로고
    • Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice
    • Musa, M., Wilson, K., Sun, L., Mulay, A., Bingle, L., Marriott, H. M., LeClair, E. E. and Bingle, C. D. (2012). Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice. Cell Tissue Res. 350, 455-464.
    • (2012) Cell Tissue Res , vol.350 , pp. 455-464
    • Musa, M.1    Wilson, K.2    Sun, L.3    Mulay, A.4    Bingle, L.5    Marriott, H.M.6    Leclair, E.E.7    Bingle, C.D.8
  • 40
    • 84924867060 scopus 로고    scopus 로고
    • Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations
    • Pardo-Saganta, A., Law, B. M., Tata, P. R., Villoria, J., Saez, B., Mou, H., Zhao, R. and Rajagopal, J. (2015). Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations. Cell Stem Cell 16, 184-197.
    • (2015) Cell Stem Cell , vol.16 , pp. 184-197
    • Pardo-Saganta, A.1    Law, B.M.2    Tata, P.R.3    Villoria, J.4    Saez, B.5    Mou, H.6    Zhao, R.7    Rajagopal, J.8
  • 41
    • 80052528051 scopus 로고    scopus 로고
    • Primary epithelial cell models for cystic fibrosis research
    • Randell, S. H., Fulcher, M. L., O’Neal, W. and Olsen, J. C. (2011). Primary epithelial cell models for cystic fibrosis research. Methods Mol. Biol. 742, 285-310.
    • (2011) Methods Mol. Biol , vol.742 , pp. 285-310
    • Randell, S.H.1    Fulcher, M.L.2    O’Neal, W.3    Olsen, J.C.4
  • 42
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins, E. L., Okubo, T., Xue, Y., Brass, D. M., Auten, R. L., Hasegawa, H., Wang, F. and Hogan, B. L. M. (2009). The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell 4, 525-534.
    • (2009) Cell Stem Cell , vol.4 , pp. 525-534
    • Rawlins, E.L.1    Okubo, T.2    Xue, Y.3    Brass, D.M.4    Auten, R.L.5    Hasegawa, H.6    Wang, F.7    Hogan, B.L.M.8
  • 43
    • 80054030182 scopus 로고    scopus 로고
    • Epithelial progenitor cells in lung development, maintenance, repair, and disease
    • Rock, J. R. and Hogan, B. L. M. (2011). Epithelial progenitor cells in lung development, maintenance, repair, and disease. Annu. Rev. Cell Dev. Biol. 27, 493-512.
    • (2011) Annu. Rev. Cell Dev. Biol , vol.27 , pp. 493-512
    • Rock, J.R.1    Hogan, B.L.M.2
  • 45
    • 77956538031 scopus 로고    scopus 로고
    • Airway basal stem cells: A perspective on their roles in epithelial homeostasis and remodeling
    • Rock, J. R., Randell, S. H. and Hogan, B. L. M. (2010). Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis. Model. Mech. 3, 545-556.
    • (2010) Dis. Model. Mech , vol.3 , pp. 545-556
    • Rock, J.R.1    Randell, S.H.2    Hogan, B.L.M.3
  • 51
    • 84959287405 scopus 로고    scopus 로고
    • BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors
    • Tadokoro, T., Gao, X., Hong, C. C., Hotten, D. and Hogan, B. L. M. (2016). BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. Development 143, 764-773.
    • (2016) Development , vol.143 , pp. 764-773
    • Tadokoro, T.1    Gao, X.2    Hong, C.C.3    Hotten, D.4    Hogan, B.L.M.5
  • 52
    • 84964216432 scopus 로고    scopus 로고
    • Developmental origin of lung macrophage diversity
    • Tan, S. Y. S. and Krasnow, M. A. (2016). Developmental origin of lung macrophage diversity. Development 143, 1318-1327.
    • (2016) Development , vol.143 , pp. 1318-1327
    • Tan, S.Y.S.1    Krasnow, M.A.2
  • 53
    • 85015279062 scopus 로고    scopus 로고
    • Plasticity in the lung: Making and breaking cell identity
    • Tata, P. R. and Rajagopal, J. (2017). Plasticity in the lung: making and breaking cell identity. Development 144, 755-766.
    • (2017) Development , vol.144 , pp. 755-766
    • Tata, P.R.1    Rajagopal, J.2
  • 58
  • 59
    • 85035016321 scopus 로고    scopus 로고
    • Airway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiation
    • Vladar, E. K., Nayak, J. V., Milla, C. E. and Axelrod, J. D. (2016). Airway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiation. JCI Insight 1, pii: e88027.
    • (2016) JCI Insight , vol.1
    • Vladar, E.K.1    Nayak, J.V.2    Milla, C.E.3    Axelrod, J.D.4
  • 61
    • 84926637156 scopus 로고    scopus 로고
    • Respiratory epithelial cells orchestrate pulmonary innate immunity
    • Whitsett, J. A. and Alenghat, T. (2015). Respiratory epithelial cells orchestrate pulmonary innate immunity. Nat. Immunol. 16, 27-35.
    • (2015) Nat. Immunol , vol.16 , pp. 27-35
    • Whitsett, J.A.1    Alenghat, T.2
  • 62
    • 77951909085 scopus 로고    scopus 로고
    • Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease
    • Whitsett, J. A., Wert, S. E. and Weaver, T. E. (2010). Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annu. Rev. Med. 61, 105-119.
    • (2010) Annu. Rev. Med , vol.61 , pp. 105-119
    • Whitsett, J.A.1    Wert, S.E.2    Weaver, T.E.3
  • 63
    • 84866067664 scopus 로고    scopus 로고
    • Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein
    • Wong, A. P., Bear, C. E., Chin, S., Pasceri, P., Thompson, T. O., Huan, L.-J., Ratjen, F., Ellis, J. and Rossant, J. (2012). Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nat. Biotechnol. 30, 876-882.
    • (2012) Nat. Biotechnol , vol.30 , pp. 876-882
    • Wong, A.P.1    Bear, C.E.2    Chin, S.3    Pasceri, P.4    Thompson, T.O.5    Huan, L.-J.6    Ratjen, F.7    Ellis, J.8    Rossant, J.9
  • 64
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang, J.-H., Chung, T. D. and Oldenburg, K. R. (1999). A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J. Biomol. Screen. 4, 67-73.
    • (1999) J. Biomol. Screen , vol.4 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.2    Oldenburg, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.