-
1
-
-
33646517058
-
Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity
-
Boey, D. et al. Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity. Diabetologia 49, 1360-70 (2006).
-
(2006)
Diabetologia
, vol.49
, pp. 1360-1370
-
-
Boey, D.1
-
2
-
-
84962413054
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann, B., Williams, G., Ghatei, M. A. & Bloom, S. R. Glucagon-like peptide-1 7-36: A physiological incretin in man. Lancet (London, England) 2, 1300-4 (1987).
-
(1987)
Lancet (London, England)
, vol.2
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
3
-
-
85022208485
-
The impact of gut hormones on the neural circuit of appetite and satiety: A systematic review
-
Zanchi, D. et al. The impact of gut hormones on the neural circuit of appetite and satiety: A systematic review. Neurosci. Biobehav. Rev. 80, 457-475 (2017).
-
(2017)
Neurosci. Biobehav. Rev.
, vol.80
, pp. 457-475
-
-
Zanchi, D.1
-
4
-
-
84984607528
-
Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery
-
Svane, M. S. et al. Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery. Int. J. Obes. (Lond). 40, 1699-1706 (2016).
-
(2016)
Int. J. Obes. (Lond).
, vol.40
, pp. 1699-1706
-
-
Svane, M.S.1
-
5
-
-
85019939659
-
The Role of PYY in pancreatic islet physiology and surgical control of diabetes
-
Guida, C., Stephen, S., Guitton, R. & Ramracheya, R. D. The Role of PYY in Pancreatic Islet Physiology and Surgical Control of Diabetes. Trends Endocrinol. Metab., https://doi.org/10.1016/j.tem.2017.04.005 (2017).
-
(2017)
Trends Endocrinol. Metab
-
-
Guida, C.1
Stephen, S.2
Guitton, R.3
Ramracheya, R.D.4
-
6
-
-
85007298368
-
Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
-
Steinert, R. E. et al. Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB. Physiol. Rev. 97 (2016).
-
(2016)
Physiol. Rev.
, vol.97
-
-
Steinert, R.E.1
-
7
-
-
84877763148
-
Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells
-
Habib, A. M., Richards, P., Rogers, G. J., Reimann, F. & Gribble, F. M. Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells. Diabetologia, https://doi.org/10.1007/s00125-013-2887-z (2013).
-
(2013)
Diabetologia
-
-
Habib, A.M.1
Richards, P.2
Rogers, G.J.3
Reimann, F.4
Gribble, F.M.5
-
8
-
-
84888204421
-
Molecular mechanisms of incretin hormone secretion
-
Ezcurra, M., Reimann, F., Gribble, F. M. & Emery, E. Molecular mechanisms of incretin hormone secretion. Curr. Opin. Pharmacol. 13, 922-7 (2013).
-
(2013)
Curr. Opin. Pharmacol.
, vol.13
, pp. 922-927
-
-
Ezcurra, M.1
Reimann, F.2
Gribble, F.M.3
Emery, E.4
-
9
-
-
0023276469
-
Short chain fatty acids in human large intestine, portal, hepatic and venous blood
-
Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P. & Macfarlane, G. T. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28, 1221-7 (1987).
-
(1987)
Gut
, vol.28
, pp. 1221-1227
-
-
Cummings, J.H.1
Pomare, E.W.2
Branch, W.J.3
Naylor, C.P.4
Macfarlane, G.T.5
-
10
-
-
0038363378
-
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
-
Brown, A. J. et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J. Biol. Chem. 278, 11312-9 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11312-11319
-
-
Brown, A.J.1
-
11
-
-
0038491435
-
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation
-
Le Poul, E. et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J. Biol. Chem. 278, 25481-9 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25481-25489
-
-
Le Poul, E.1
-
12
-
-
66149084058
-
GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
-
Thangaraju, M. et al. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer Res. 69, 2826-32 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 2826-2832
-
-
Thangaraju, M.1
-
13
-
-
0017886958
-
Sodium butyrate inhibits histone deacetylation in cultured cells
-
Candido, E. P., Reeves, R. & Davie, J. R. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell 14, 105-13 (1978).
-
(1978)
Cell
, vol.14
, pp. 105-113
-
-
Candido, E.P.1
Reeves, R.2
Davie, J.R.3
-
14
-
-
79953216793
-
Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: Identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3
-
Schmidt, J. et al. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. J. Biol. Chem. 286, 10628-40 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 10628-10640
-
-
Schmidt, J.1
-
15
-
-
84870361150
-
Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3
-
Hudson, B. D., Tikhonova, I. G., Pandey, S. K., Ulven, T. & Milligan, G. Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3. J. Biol. Chem. 287, 41195-209 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 41195-41209
-
-
Hudson, B.D.1
Tikhonova, I.G.2
Pandey, S.K.3
Ulven, T.4
Milligan, G.5
-
16
-
-
0038676409
-
Inhibition of histone deacetylase activity by butyrate
-
Davie, J. R. Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133, 2485S-2493S (2003).
-
(2003)
J. Nutr.
, vol.133
, pp. 2485S-2493S
-
-
Davie, J.R.1
-
17
-
-
84979085632
-
Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms
-
Thakur, B. K., Dasgupta, N., Ta, A. & Das, S. Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms. Nucleic Acids Res. 44, 5658-72 (2016).
-
(2016)
Nucleic Acids Res.
, vol.44
, pp. 5658-5672
-
-
Thakur, B.K.1
Dasgupta, N.2
Ta, A.3
Das, S.4
-
18
-
-
77952744684
-
Butyrate and propionate induced activated or non-Activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways
-
Aoyama, M., Kotani, J. & Usami, M. Butyrate and propionate induced activated or non-Activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. Nutrition 26, 653-61 (2010).
-
(2010)
Nutrition
, vol.26
, pp. 653-661
-
-
Aoyama, M.1
Kotani, J.2
Usami, M.3
-
19
-
-
0032445520
-
Short-chain fatty acids modify colonic motility through nerves and polypeptide YY release in the rat
-
Cherbut, C. et al. Short-chain fatty acids modify colonic motility through nerves and polypeptide YY release in the rat. Am J Physiol Gastrointest Liver Physiol 275, G1415-1422 (1998).
-
(1998)
Am J Physiol Gastrointest Liver Physiol
, vol.275
, pp. G1415-1422
-
-
Cherbut, C.1
-
20
-
-
55949091259
-
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-Acid binding G protein-coupled receptor, Gpr41
-
Samuel, B. S. et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-Acid binding G protein-coupled receptor, Gpr41. Proc. Natl. Acad. Sci. USA 105, 16767-72 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16767-16772
-
-
Samuel, B.S.1
-
21
-
-
23044477428
-
Impact of inulin and oligofructose on gastrointestinal peptides
-
Delzenne, N. M., Cani, P. D., Daubioul, C. & Neyrinck, A. M. Impact of inulin and oligofructose on gastrointestinal peptides. Br. J. Nutr. 93(Suppl 1), S157-61 (2005).
-
(2005)
Br. J. Nutr.
, vol.93
, pp. S157-S161
-
-
Delzenne, N.M.1
Cani, P.D.2
Daubioul, C.3
Neyrinck, A.M.4
-
22
-
-
84856509724
-
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
-
Tolhurst, G. et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 61, 364-71 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 364-371
-
-
Tolhurst, G.1
-
23
-
-
84924700879
-
The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents
-
Psichas, A. et al. The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents. Int. J. Obes. 39, 424-9 (2015).
-
(2015)
Int. J. Obes.
, vol.39
, pp. 424-429
-
-
Psichas, A.1
-
24
-
-
84952338130
-
Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models
-
Forbes, S. et al. Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models. Diabetes 64, 3763-3771 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 3763-3771
-
-
Forbes, S.1
-
25
-
-
34547965812
-
Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats
-
Cani, P. D., Hoste, S., Guiot, Y. & Delzenne, N. M. Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats. Br. J. Nutr. 98, 32-7 (2007).
-
(2007)
Br. J. Nutr.
, vol.98
, pp. 32-37
-
-
Cani, P.D.1
Hoste, S.2
Guiot, Y.3
Delzenne, N.M.4
-
26
-
-
84893087602
-
Generation of L cells in mouse and human small intestine organoids
-
Petersen, N. et al. Generation of L cells in mouse and human small intestine organoids. Diabetes 63, 410-20 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 410-420
-
-
Petersen, N.1
-
27
-
-
85008657161
-
Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety
-
Brooks, L. et al. Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety. Mol. Metab. 6, 48-60 (2017).
-
(2017)
Mol. Metab.
, vol.6
, pp. 48-60
-
-
Brooks, L.1
-
28
-
-
33846793153
-
Peptide YY and proglucagon mRNA expression patterns and regulation in the gut
-
Zhou, J. et al. Peptide YY and proglucagon mRNA expression patterns and regulation in the gut. Obesity (Silver Spring). 14, 683-9 (2006).
-
(2006)
Obesity (Silver Spring).
, vol.14
, pp. 683-689
-
-
Zhou, J.1
-
29
-
-
84945202481
-
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
-
Chambers, E. S. et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut 64, 1744-54 (2015).
-
(2015)
Gut
, vol.64
, pp. 1744-1754
-
-
Chambers, E.S.1
-
30
-
-
70149102106
-
Expression of short-chain fatty acid receptor GPR41 in the human colon
-
Tazoe, H. et al. Expression of short-chain fatty acid receptor GPR41 in the human colon. Biomed. Res. 30, 149-56 (2009).
-
(2009)
Biomed. Res.
, vol.30
, pp. 149-156
-
-
Tazoe, H.1
-
31
-
-
0034812998
-
A Human Cellular Model for Studying the Regulation of Glucagon-Like Peptide-1 Secretion
-
Reimer, R. A. A Human Cellular Model for Studying the Regulation of Glucagon-Like Peptide-1 Secretion. Endocrinology 142, 4522-4528 (2001).
-
(2001)
Endocrinology
, vol.142
, pp. 4522-4528
-
-
Reimer, R.A.1
-
32
-
-
33751100128
-
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon
-
Rozengurt, N. et al. Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. Am. J. Physiol. Gastrointest. Liver Physiol. 291, G792-802 (2006).
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.291
, pp. G792-802
-
-
Rozengurt, N.1
-
33
-
-
84984870564
-
A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias
-
Bolognini, D. et al. A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias. J. Biol. Chem. 291, 18915-31 (2016).
-
(2016)
J. Biol. Chem.
, vol.291
, pp. 18915-18931
-
-
Bolognini, D.1
-
34
-
-
33947313218
-
HDACs, histone deacetylation and gene transcription: From molecular biology to cancer therapeutics
-
Gallinari, P., Marco, S., Jones, P., Pallaoro, M. & Steinkühler, C. HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res. 17, 195 (2007).
-
(2007)
Cell Res.
, vol.17
, pp. 195
-
-
Gallinari, P.1
Marco, S.2
Jones, P.3
Pallaoro, M.4
Steinkühler, P.5
-
35
-
-
36048958965
-
Histone Deacetylase Inhibitors: Overview and Perspectives
-
Dokmanovic, M., Clarke, C. & Marks, P. A. Histone Deacetylase Inhibitors: Overview and Perspectives. Mol. Cancer Res. 5, 981-989 (2007).
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 981-989
-
-
Dokmanovic, M.1
Clarke, C.2
Marks, P.A.3
-
36
-
-
56449093424
-
Glucose sensing in L cells: A primary cell study
-
Reimann, F. et al. Glucose sensing in L cells: A primary cell study. Cell Metab. 8, 532-9 (2008).
-
(2008)
Cell Metab.
, vol.8
, pp. 532-539
-
-
Reimann, F.1
-
37
-
-
84949547309
-
Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases
-
Lin, M. Y., de Zoete, M. R., van Putten, J. P. M. & Strijbis, K. Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases. Front. Immunol. 6, 554 (2015).
-
(2015)
Front. Immunol.
, vol.6
, pp. 554
-
-
Lin, M.Y.1
De Zoete, M.R.2
Van Putten, J.P.M.3
Strijbis, K.4
-
38
-
-
84982994263
-
TLR Ligands and Butyrate Increase Pyy expression through two distinct but inter-regulated pathways
-
Larraufie, P., Doré, J., Lapaque, N. & Blottière, H. M. TLR Ligands and Butyrate Increase Pyy Expression through Two Distinct but Inter-regulated Pathways. Cell. Microbiol, https://doi.org/10.1111/cmi.12648 (2016).
-
(2016)
Cell. Microbiol
-
-
Larraufie, P.1
Doré, J.2
Lapaque, N.3
Blottière, H.M.4
-
39
-
-
66849129539
-
Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults
-
Parnell, J. A. & Reimer, R. A. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am. J. Clin. Nutr. 89, 1751-9 (2009).
-
(2009)
Am. J. Clin. Nutr.
, vol.89
, pp. 1751-1759
-
-
Parnell, J.A.1
Reimer, R.A.2
-
40
-
-
70350662669
-
Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal
-
Cani, P. D. et al. Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. Am. J. Clin. Nutr. 90, 1236-43 (2009).
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 1236-1243
-
-
Cani, P.D.1
-
41
-
-
84883110880
-
Richness of human gut microbiome correlates with metabolic markers
-
Le Chatelier, E. et al. Richness of human gut microbiome correlates with metabolic markers. Nature 500, 541-6 (2013).
-
(2013)
Nature
, vol.500
, pp. 541-546
-
-
Le Chatelier, E.1
-
42
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-23 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
|