Therapeutic potential of novel twin compounds containing tetramethylpyrazine and carnitine substructures in experimental ischemic stroke

Oxidative Medicine and Cellular Longevity

Volumn 2017, Issue , 2017, Pages

  Wang, Ziying ^a,b   Zhou, Zhuanli ^a   Wei, Xinbing ^a   Wang, Mingwei ^a   Wang, Bi Ou ^a   Zhang, Yanan ^a   He, Xiaoting ^a   Sun, Yu ^a   Wang, Xiaojie ^a   Sun, Mingcheng ^a   Gong, Xiaowei ^b   Yi, Fan ^a   Zhang, Yan ^a  

^a SHANDONG UNIVERSITY   (China)

^b Department of Radiation Oncology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH;

BLOOD-BRAIN BARRIER; CALCIUM OVERLOAD; CEREBRAL ISCHEMIA; INFLAMMATORY RESPONSE; NEUROPROTECTIVE EFFECTS; THERAPEUTIC POTENTIALS; THERAPEUTIC STRATEGY; THERAPEUTIC TARGETS;

BRAIN;

CARNITINE DERIVATIVE; LR 102; LR 109; LR 120; LR 134; LR 137; LR 140; LR 143; LR 146; LR 149; LR 152; NEUROPROTECTIVE AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TETRAMETHYLPYRAZINE; UNCLASSIFIED DRUG; CARNITINE; CYBB PROTEIN, RAT; PYRAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INFARCTION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; EC50; ENERGY METABOLISM; EXPERIMENTAL CEREBRAL ISCHEMIA; IN VIVO STUDY; MALE; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; ANIMAL; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CHEMISTRY; DISEASE MODEL; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

CHEMICAL COMPOUNDS; DIAGNOSIS; DISEASES; MEDICINE;

ANIMALS; BRAIN ISCHEMIA; CARNITINE; DISEASE MODELS, ANIMAL; MALE; NADPH OXIDASE 2; NEUROPROTECTIVE AGENTS; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; STROKE;

EID: 85042599497     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2017/7191856     Document Type: Article

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