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Volumn 18, Issue 12, 2013, Pages 1400-1417

Which NADPH oxidase isoform is relevant for ischemic stroke? the case for Nox 2

Author keywords

[No Author keywords available]

Indexed keywords

ALISKIREN; ANTIOXIDANT; APOCYNIN; CANDESARTAN; DISUFENTON SODIUM; ENZYME INHIBITOR; GENKYOTEX; HONOKIOL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLUMBAGIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; UNCLASSIFIED DRUG; VAS 2870;

EID: 84875158695     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4721     Document Type: Article
Times cited : (107)

References (189)
  • 2
    • 33846818524 scopus 로고    scopus 로고
    • Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
    • Abramov AY, Scorziello A, and Duchen MR. Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J Neurosci 27: 1129-1138, 2007..
    • (2007) J Neurosci , vol.27 , pp. 1129-1138
    • Abramov, A.Y.1    Scorziello, A.2    Duchen, M.R.3
  • 3
    • 71549144988 scopus 로고    scopus 로고
    • Lipid oxidation and peroxidation in CNS health and disease: From molecular mechanisms to therapeutic opportunities
    • Adibhatla RM and Hatcher JF. Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 12: 125-169, 2010..
    • (2010) Antioxid Redox Signal , vol.12 , pp. 125-169
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 8
    • 79957935719 scopus 로고    scopus 로고
    • NADPH-oxidase activation and cognition in Alzheimer disease progression
    • Ansari MA and Scheff SW. NADPH-oxidase activation and cognition in Alzheimer disease progression. Free Radic Biol Med 51: 171-178, 2011..
    • (2011) Free Radic Biol Med , vol.51 , pp. 171-178
    • Ansari, M.A.1    Scheff, S.W.2
  • 11
    • 84862929090 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the efficacy of statins in experimental stroke
    • Baryan HK, Allan SM, Vail A, and Smith CJ. Systematic review and meta-analysis of the efficacy of statins in experimental stroke. Int J Stroke 7: 150-156, 2012..
    • (2012) Int J Stroke , vol.7 , pp. 150-156
    • Baryan, H.K.1    Allan, S.M.2    Vail, A.3    Smith, C.J.4
  • 12
    • 80051551971 scopus 로고    scopus 로고
    • Anoxia-reoxygenation enhances platelet thromboxane A2 production via reactive oxygen species-generated NOX2: Effect in patients undergoing elective percutaneous coronary intervention
    • Basili S, Pignatelli P, Tanzilli G, Mangieri E, Carnevale R, Nocella C, Di Santo S, Pastori D, Ferroni P, and Violi F. Anoxia-reoxygenation enhances platelet thromboxane A2 production via reactive oxygen species-generated NOX2: effect in patients undergoing elective percutaneous coronary intervention. Arterioscler Thromb Vasc Biol 31: 1766-1771, 2011..
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1766-1771
    • Basili, S.1    Pignatelli, P.2    Tanzilli, G.3    Mangieri, E.4    Carnevale, R.5    Nocella, C.6    Di Santo, S.7    Pastori, D.8    Ferroni, P.9    Violi, F.10
  • 13
    • 84856224124 scopus 로고    scopus 로고
    • NOX5: From basic biology to signaling and disease
    • Bedard K, Jaquet V, and Krause KH. NOX5: from basic biology to signaling and disease. Free Radic Biol Med 52: 725-734, 2012..
    • (2012) Free Radic Biol Med , vol.52 , pp. 725-734
    • Bedard, K.1    Jaquet, V.2    Krause, K.H.3
  • 14
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROSgenerating NADPH oxidases: Physiology and pathophysiology
    • Bedard K and Krause KH. The NOX family of ROSgenerating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007..
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 15
    • 34547852400 scopus 로고    scopus 로고
    • NOX family NADPH oxidases: Not just in mammals
    • Bedard K, Lardy B, and Krause KH. NOX family NADPH oxidases: not just in mammals. Biochimie 89: 1107-1112, 2007..
    • (2007) Biochimie , vol.89 , pp. 1107-1112
    • Bedard, K.1    Lardy, B.2    Krause, K.H.3
  • 16
    • 36848999339 scopus 로고    scopus 로고
    • Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase
    • Behrens MM, Ali SS, Dao DN, Lucero J, Shekhtman G, Quick KL, and Dugan LL. Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. Science 318: 1645-1647, 2007..
    • (2007) Science , vol.318 , pp. 1645-1647
    • Behrens, M.M.1    Ali, S.S.2    Dao, D.N.3    Lucero, J.4    Shekhtman, G.5    Quick, K.L.6    Dugan, L.L.7
  • 17
    • 58149385775 scopus 로고    scopus 로고
    • Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia
    • Behrens MM, Ali SS, and Dugan LL. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. J Neurosci 28: 13957-13966, 2008..
    • (2008) J Neurosci , vol.28 , pp. 13957-13966
    • Behrens, M.M.1    Ali, S.S.2    Dugan, L.L.3
  • 18
    • 67650652986 scopus 로고    scopus 로고
    • Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex?
    • Behrens MM and Sejnowski TJ. Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex? Neuropharmacology 57: 193-200, 2009..
    • (2009) Neuropharmacology , vol.57 , pp. 193-200
    • Behrens, M.M.1    Sejnowski, T.J.2
  • 19
    • 28744434554 scopus 로고    scopus 로고
    • Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning
    • Bell RM, Cave AC, Johar S, Hearse DJ, Shah AM and Shattock MJ. Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning. FASEB J 19: 2037-2039, 2005..
    • (2005) FASEB J , vol.19 , pp. 2037-2039
    • Bell, R.M.1    Cave, A.C.2    Johar, S.3    Hearse, D.J.4    Shah, A.M.5    Shattock, M.J.6
  • 21
    • 57449110125 scopus 로고    scopus 로고
    • NADPH oxidase as a therapeutic target in Alzheimer's disease
    • Block ML. NADPH oxidase as a therapeutic target in Alzheimer's disease. BMC Neurosci 9 Suppl 2: S8, 2008..
    • (2008) BMC Neurosci , vol.9 , Issue.SUPPL. 2
    • Block, M.L.1
  • 22
    • 0034821770 scopus 로고    scopus 로고
    • Mapping of quantitative trait loci with knockout/congenic strains
    • Bolivar VJ, Cook MN, and Flaherty L. Mapping of quantitative trait loci with knockout/congenic strains. Genome research 11: 1549-1552, 2001..
    • (2001) Genome Research , vol.11 , pp. 1549-1552
    • Bolivar, V.J.1    Cook, M.N.2    Flaherty, L.3
  • 23
    • 0345690184 scopus 로고    scopus 로고
    • Role of NADPH oxidases in the control of vascular gene expression
    • Brandes RP. Role of NADPH oxidases in the control of vascular gene expression. Antioxid Redox Signal 5: 803-811, 2003..
    • (2003) Antioxid Redox Signal , vol.5 , pp. 803-811
    • Brandes, R.P.1
  • 25
    • 70349804297 scopus 로고    scopus 로고
    • Nox proteins in signal transduction
    • Brown DI and Griendling KK. Nox proteins in signal transduction. Free Radic Biol Med 47: 1239-1253, 2009..
    • (2009) Free Radic Biol Med , vol.47 , pp. 1239-1253
    • Brown, D.I.1    Griendling, K.K.2
  • 27
    • 20044386906 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis in cultured bovine retinal pericytes: Roles of NAD(P)H oxidase, oxidant stress, and ceramide
    • Cacicedo JM, Benjachareowong S, Chou E, Ruderman NB, and Ido Y. Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide. Diabetes 54: 1838-1845, 2005..
    • (2005) Diabetes , vol.54 , pp. 1838-1845
    • Cacicedo, J.M.1    Benjachareowong, S.2    Chou, E.3    Ruderman, N.B.4    Ido, Y.5
  • 28
    • 0035724654 scopus 로고    scopus 로고
    • Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2 + )/calmodulin-dependent protein kinase II/ janus kinase 2-dependent pathway
    • Cai H, Davis ME, Drummond GR, and Harrison DG. Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2 + )/calmodulin-dependent protein kinase II/ janus kinase 2-dependent pathway. Arterioscler Thromb Vasc Biol 21: 1571-1576, 2001..
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1571-1576
    • Cai, H.1    Davis, M.E.2    Drummond, G.R.3    Harrison, D.G.4
  • 29
    • 78651313012 scopus 로고    scopus 로고
    • The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension
    • Capone C, Faraco G, Park L, Cao X, Davisson RL, and Iadecola C. The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. Am J Physiol Heart Circ Physiol 300: H397-H407, 2011..
    • (2011) Am J Physiol Heart Circ Physiol , vol.300
    • Capone, C.1    Faraco, G.2    Park, L.3    Cao, X.4    Davisson, R.L.5    Iadecola, C.6
  • 31
    • 0028351503 scopus 로고
    • Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat
    • Chen H, Chopp M, Zhang RL, Bodzin G, Chen Q, Rusche JR, and Todd RF, III. Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat. Ann Neurol 35: 458-463, 1994..
    • (1994) Ann Neurol , vol.35 , pp. 458-463
    • Chen, H.1    Chopp, M.2    Zhang, R.L.3    Bodzin, G.4    Chen, Q.5    Rusche, J.R.6    Todd Iii, R.F.7
  • 32
    • 79954628624 scopus 로고    scopus 로고
    • NADPH oxidase is involved in post-ischemic brain inflammation
    • Chen H, Kim GS, Okami N, Narasimhan P, and Chan PH. NADPH oxidase is involved in post-ischemic brain inflammation. Neurobiol Dis 42: 341-348, 2011..
    • (2011) Neurobiol Dis , vol.42 , pp. 341-348
    • Chen, H.1    Kim, G.S.2    Okami, N.3    Narasimhan, P.4    Chan, P.H.5
  • 33
    • 67649852282 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion
    • Chen H, Song YS, and Chan PH. Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. J Cereb Blood Flow Metab 29: 1262-1272, 2009..
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1262-1272
    • Chen, H.1    Song, Y.S.2    Chan, P.H.3
  • 36
    • 54449093276 scopus 로고    scopus 로고
    • The role of oxidative stress and NADPH oxidase in cerebrovascular disease
    • Chrissobolis S and Faraci FM. The role of oxidative stress and NADPH oxidase in cerebrovascular disease. Trends Mol Med 14: 495-502, 2008..
    • (2008) Trends Mol Med , vol.14 , pp. 495-502
    • Chrissobolis, S.1    Faraci, F.M.2
  • 37
    • 1542345696 scopus 로고    scopus 로고
    • Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions
    • Collins R, Armitage J, Parish S, Sleight P, and Peto R. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet 363: 757-767, 2004..
    • (2004) Lancet , vol.363 , pp. 757-767
    • Collins, R.1    Armitage, J.2    Parish, S.3    Sleight, P.4    Peto, R.5
  • 38
    • 80054870318 scopus 로고    scopus 로고
    • Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis
    • Connell BJ, Saleh MC, Khan BV, and Saleh TM. Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis. Food Chem Toxicol 49: 3063-3069, 2011..
    • (2011) Food Chem Toxicol , vol.49 , pp. 3063-3069
    • Connell, B.J.1    Saleh, M.C.2    Khan, B.V.3    Saleh, T.M.4
  • 39
    • 53049091077 scopus 로고    scopus 로고
    • Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons
    • Coyoy A, Valencia A, Guemez-Gamboa A, and Moran J. Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons. Free Radic Biol Med 45: 1056-1064, 2008..
    • (2008) Free Radic Biol Med , vol.45 , pp. 1056-1064
    • Coyoy, A.1    Valencia, A.2    Guemez-Gamboa, A.3    Moran, J.4
  • 42
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
    • D'Autreaux B and Toledano MB. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 8: 813-824, 2007..
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 813-824
    • D'Autreaux, B.1    Toledano, M.B.2
  • 43
  • 44
    • 82555185635 scopus 로고    scopus 로고
    • Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke
    • De Silva TM, Brait VH, Drummond GR, Sobey CG, and Miller AA. Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke. PLoS One 6: e28393, 2011..
    • (2011) PLoS One , vol.6
    • De Silva, T.M.1    Brait, V.H.2    Drummond, G.R.3    Sobey, C.G.4    Miller, A.A.5
  • 46
    • 80052266526 scopus 로고    scopus 로고
    • Cross talk between mitochondria and NADPH oxidases
    • Dikalov S. Cross talk between mitochondria and NADPH oxidases. Free Radic Biol Med 51: 1289-1301, 2011..
    • (2011) Free Radic Biol Med , vol.51 , pp. 1289-1301
    • Dikalov, S.1
  • 48
    • 11144322792 scopus 로고    scopus 로고
    • Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone
    • Ding Y, Chen ZJ, Liu S, Che D, Vetter M, and Chang CH. Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone. J Pharm Pharmacol 57: 111-116, 2005..
    • (2005) J Pharm Pharmacol , vol.57 , pp. 111-116
    • Ding, Y.1    Chen, Z.J.2    Liu, S.3    Che, D.4    Vetter, M.5    Chang, C.H.6
  • 49
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, and Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 22: 391-397, 1999..
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 50
    • 0033866614 scopus 로고    scopus 로고
    • Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury
    • Dodd OJ and Pearse DB. Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury. Am J Physiol Heart Circ Physiol 279: H303-H312, 2000..
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Dodd, O.J.1    Pearse, D.B.2
  • 52
    • 33645808484 scopus 로고    scopus 로고
    • NAD(P)H oxidase contributes to the progression of remote hepatic parenchymal injury and endothelial dysfunction, but not microvascular perfusion deficits
    • Dorman RB, Wunder C, Saba H, Shoemaker JL, MacMillan-Crow LA, and Brock RW. NAD(P)H oxidase contributes to the progression of remote hepatic parenchymal injury and endothelial dysfunction, but not microvascular perfusion deficits. Am J Physiol Gastrointest Liver Physiol 290: G1025-G1032, 2006..
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Dorman, R.B.1    Wunder, C.2    Saba, H.3    Shoemaker, J.L.4    Macmillan-Crow, L.A.5    Brock, R.W.6
  • 53
    • 0033952940 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
    • Drummond GR, Cai H, Davis ME, Ramasamy S, and Harrison DG. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ Res 86: 347-354, 2000..
    • (2000) Circ Res , vol.86 , pp. 347-354
    • Drummond, G.R.1    Cai, H.2    Davis, M.E.3    Ramasamy, S.4    Harrison, D.G.5
  • 55
    • 80053302109 scopus 로고    scopus 로고
    • Behavioral and genetic investigations of low exploratory behavior in Il18r1(-/-) mice: We can't always blame it on the targeted gene
    • Eisener-Dorman AF, Lawrence DA, and Bolivar VJ. Behavioral and genetic investigations of low exploratory behavior in Il18r1(-/-) mice: we can't always blame it on the targeted gene. Brain Behav Immun 24: 1116-1125, 2010..
    • (2010) Brain Behav Immun , vol.24 , pp. 1116-1125
    • Eisener-Dorman, A.F.1    Lawrence, D.A.2    Bolivar, V.J.3
  • 56
    • 33748996772 scopus 로고    scopus 로고
    • Discontinuation of statin treatment in stroke patients
    • Endres M and Laufs U. Discontinuation of statin treatment in stroke patients. Stroke 37: 2640-2643, 2006..
    • (2006) Stroke , vol.37 , pp. 2640-2643
    • Endres, M.1    Laufs, U.2
  • 57
    • 33747784874 scopus 로고    scopus 로고
    • Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats
    • Engelhorn T, Doerfler A, Heusch G, and Schulz R. Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats. Neurosci Lett 406: 92-96, 2006..
    • (2006) Neurosci Lett , vol.406 , pp. 92-96
    • Engelhorn, T.1    Doerfler, A.2    Heusch, G.3    Schulz, R.4
  • 58
    • 33645732870 scopus 로고    scopus 로고
    • Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production
    • Erdos B, Snipes JA, Tulbert CD, Katakam P, Miller AW, and Busija DW. Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production. Am J Physiol Heart Circ Physiol 290: H1264-H1270, 2006..
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Erdos, B.1    Snipes, J.A.2    Tulbert, C.D.3    Katakam, P.4    Miller, A.W.5    Busija, D.W.6
  • 59
    • 59049099466 scopus 로고    scopus 로고
    • NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells
    • Espinosa A, Garcia A, Hartel S, Hidalgo C, and Jaimovich E. NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells. J Biol Chem 284: 2568-2575, 2009..
    • (2009) J Biol Chem , vol.284 , pp. 2568-2575
    • Espinosa, A.1    Garcia, A.2    Hartel, S.3    Hidalgo, C.4    Jaimovich, E.5
  • 61
    • 32844454895 scopus 로고    scopus 로고
    • Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX
    • Frantz S, Brandes RP, Hu K, Rammelt K, Wolf J, Scheuermann H, Ertl G, and Bauersachs J. Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX. Basic Res Cardiol 101: 127-132, 2006..
    • (2006) Basic Res Cardiol , vol.101 , pp. 127-132
    • Frantz, S.1    Brandes, R.P.2    Hu, K.3    Rammelt, K.4    Wolf, J.5    Scheuermann, H.6    Ertl, G.7    Bauersachs, J.8
  • 63
    • 70349316712 scopus 로고    scopus 로고
    • Nox5 and the regulation of cellular function
    • Fulton DJ. Nox5 and the regulation of cellular function. Antioxid Redox Signal 11: 2443-2452, 2009..
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2443-2452
    • Fulton, D.J.1
  • 65
    • 79151470304 scopus 로고    scopus 로고
    • Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats
    • Genovese T, Mazzon E, Paterniti I, Esposito E, Bramanti P, and Cuzzocrea S. Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats. Brain Res 1372: 92-102, 2011..
    • (2011) Brain Res , vol.1372 , pp. 92-102
    • Genovese, T.1    Mazzon, E.2    Paterniti, I.3    Esposito, E.4    Bramanti, P.5    Cuzzocrea, S.6
  • 67
    • 62949204563 scopus 로고    scopus 로고
    • Current status of neuroprotection for cerebral ischemia: Synoptic overview
    • Ginsberg MD. Current status of neuroprotection for cerebral ischemia: synoptic overview. Stroke 40: S111-S114, 2009..
    • (2009) Stroke , vol.40
    • Ginsberg, M.D.1
  • 68
    • 33646710114 scopus 로고    scopus 로고
    • Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals
    • Girouard H, Park L, Anrather J, Zhou P, and Iadecola C. Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals. Arterioscler Thromb Vasc Biol 26: 826-832, 2006..
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 826-832
    • Girouard, H.1    Park, L.2    Anrather, J.3    Zhou, P.4    Iadecola, C.5
  • 70
  • 71
    • 2542551340 scopus 로고    scopus 로고
    • Reperfusioninduced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia
    • Gursoy-Ozdemir Y, Can A, and Dalkara T. Reperfusioninduced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia. Stroke 35: 1449-1453, 2004..
    • (2004) Stroke , vol.35 , pp. 1449-1453
    • Gursoy-Ozdemir, Y.1    Can, A.2    Dalkara, T.3
  • 75
    • 50849098818 scopus 로고    scopus 로고
    • Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: The role of NADPH oxidases
    • Harrigan TJ, Abdullaev IF, Jourd'heuil D, and Mongin AA. Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases. J Neurochem 106: 2449-2462, 2008..
    • (2008) J Neurochem , vol.106 , pp. 2449-2462
    • Harrigan, T.J.1    Abdullaev, I.F.2    Jourd'Heuil, D.3    Mongin, A.A.4
  • 79
    • 33751182650 scopus 로고    scopus 로고
    • Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke
    • Hong H, Zeng JS, Kreulen DL, Kaufman DI, and Chen AF. Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke. Am J Physiol Heart Circ Physiol 291: H2210-H2215, 2006..
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Hong, H.1    Zeng, J.S.2    Kreulen, D.L.3    Kaufman, D.I.4    Chen, A.F.5
  • 80
    • 62949149460 scopus 로고    scopus 로고
    • Threats to the mind: Aging, amyloid, and hypertension
    • Iadecola C, Park L, and Capone C. Threats to the mind: aging, amyloid, and hypertension. Stroke 40: S40-S44, 2009..
    • (2009) Stroke , vol.40
    • Iadecola, C.1    Park, L.2    Capone, C.3
  • 83
    • 33744960694 scopus 로고    scopus 로고
    • NADPH oxidases of the brain: Distribution, regulation, and function
    • Infanger DW, Sharma RV, and Davisson RL. NADPH oxidases of the brain: distribution, regulation, and function. Antioxid Redox Signal. 8: 1583-1596, 2006..
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1583-1596
    • Infanger, D.W.1    Sharma, R.V.2    Davisson, R.L.3
  • 85
    • 65349159768 scopus 로고    scopus 로고
    • Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice
    • Jackman KA, Miller AA, De Silva TM, Crack PJ, Drummond GR, and Sobey CG. Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice. Br J Pharmacol 156: 680-688, 2009..
    • (2009) Br J Pharmacol , vol.156 , pp. 680-688
    • Jackman, K.A.1    Miller, A.A.2    De Silva, T.M.3    Crack, P.J.4    Drummond, G.R.5    Sobey, C.G.6
  • 86
    • 67849088501 scopus 로고    scopus 로고
    • Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke
    • Jackman KA, Miller AA, Drummond GR, and Sobey CG. Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke. Brain Res 1286: 215-220, 2009..
    • (2009) Brain Res , vol.1286 , pp. 215-220
    • Jackman, K.A.1    Miller, A.A.2    Drummond, G.R.3    Sobey, C.G.4
  • 87
    • 67651156448 scopus 로고    scopus 로고
    • Small molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets
    • Jaquet V, Scapozza L, Clark R, Krause KH, and Lambeth JD. Small molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal 11: 2535-2552, 2009..
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2535-2552
    • Jaquet, V.1    Scapozza, L.2    Clark, R.3    Krause, K.H.4    Lambeth, J.D.5
  • 88
    • 84864330120 scopus 로고    scopus 로고
    • NADPH oxidases as therapeutic targets in ischemic stroke
    • Kahles T and Brandes RP. NADPH oxidases as therapeutic targets in ischemic stroke. Cell Mol Life Sci 69: 2345-2363, 2012..
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2345-2363
    • Kahles, T.1    Brandes, R.P.2
  • 91
    • 57349180534 scopus 로고    scopus 로고
    • Antioxidants in central nervous system diseases: Preclinical promise and translational challenges
    • Kamat CD, Gadal S, Mhatre M, Williamson KS, Pye QN, and Hensley K. Antioxidants in central nervous system diseases: preclinical promise and translational challenges. J Alzheimers Dis 15: 473-493, 2008..
    • (2008) J Alzheimers Dis , vol.15 , pp. 473-493
    • Kamat, C.D.1    Gadal, S.2    Mhatre, M.3    Williamson, K.S.4    Pye, Q.N.5    Hensley, K.6
  • 92
    • 84855409770 scopus 로고    scopus 로고
    • Physiological roles of NOX/NADPH oxidase, the superoxidegenerating enzyme
    • Katsuyama M, Matsuno K, and Yabe-Nishimura C. Physiological roles of NOX/NADPH oxidase, the superoxidegenerating enzyme. J Clin Biochem Nutr 50: 9-22, 2012..
    • (2012) J Clin Biochem Nutr , vol.50 , pp. 9-22
    • Katsuyama, M.1    Matsuno, K.2    Yabe-Nishimura, C.3
  • 93
    • 8844227341 scopus 로고    scopus 로고
    • Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
    • Kazama K, Anrather J, Zhou P, Girouard H, Frys K, Milner TA, and Iadecola C. Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res 95: 1019-1026, 2004..
    • (2004) Circ Res , vol.95 , pp. 1019-1026
    • Kazama, K.1    Anrather, J.2    Zhou, P.3    Girouard, H.4    Frys, K.5    Milner, T.A.6    Iadecola, C.7
  • 95
    • 0036842342 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidase triggers delayed cerebral vasospasm after subarachnoid hemorrhage in rats
    • Kim DE, Suh YS, Lee MS, Kim KY, Lee JH, Lee HS, Hong KW, and Kim CD. Vascular NAD(P)H oxidase triggers delayed cerebral vasospasm after subarachnoid hemorrhage in rats. Stroke 33: 2687-2691, 2002..
    • (2002) Stroke , vol.33 , pp. 2687-2691
    • Kim, D.E.1    Suh, Y.S.2    Lee, M.S.3    Kim, K.Y.4    Lee, J.H.5    Lee, H.S.6    Hong, K.W.7    Kim, C.D.8
  • 97
    • 33847180453 scopus 로고    scopus 로고
    • Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species
    • Kunz A, Anrather J, Zhou P, Orio M, and Iadecola C. Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. J Cereb Blood Flow Metab 27: 545-551, 2007..
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 545-551
    • Kunz, A.1    Anrather, J.2    Zhou, P.3    Orio, M.4    Iadecola, C.5
  • 98
    • 34447128135 scopus 로고    scopus 로고
    • Neurovascular protection by ischemic tolerance: Role of nitric oxide and reactive oxygen species
    • Kunz A, Park L, Abe T, Gallo EF, Anrather J, Zhou P, and Iadecola C. Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species. J Neurosci 27: 7083-7093, 2007..
    • (2007) J Neurosci , vol.27 , pp. 7083-7093
    • Kunz, A.1    Park, L.2    Abe, T.3    Gallo, E.F.4    Anrather, J.5    Zhou, P.6    Iadecola, C.7
  • 101
    • 34347257042 scopus 로고    scopus 로고
    • Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
    • Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med 43: 332-347, 2007..
    • (2007) Free Radic Biol Med , vol.43 , pp. 332-347
    • Lambeth, J.D.1
  • 102
    • 70350340576 scopus 로고    scopus 로고
    • NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression
    • Li B, Bedard K, Sorce S, Hinz B, Dubois-Dauphin M, and Krause KH. NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression. J Innate Immun 1: 570-581, 2009..
    • (2009) J Innate Immun , vol.1 , pp. 570-581
    • Li, B.1    Bedard, K.2    Sorce, S.3    Hinz, B.4    Dubois-Dauphin, M.5    Krause, K.H.6
  • 103
    • 0242391822 scopus 로고    scopus 로고
    • Honokiol protects rat brain from focal cerebral ischemiareperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production
    • Liou KT, Shen YC, Chen CF, Tsao CM, and Tsai SK. Honokiol protects rat brain from focal cerebral ischemiareperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production. Brain Res 992: 159-166, 2003..
    • (2003) Brain Res , vol.992 , pp. 159-166
    • Liou, K.T.1    Shen, Y.C.2    Chen, C.F.3    Tsao, C.M.4    Tsai, S.K.5
  • 104
    • 48049113477 scopus 로고    scopus 로고
    • Protective effects of apocynin and allopurinol on ischemia/ reperfusioninduced liver injury in mice
    • Liu PG, He SQ, Zhang YH, and Wu J. Protective effects of apocynin and allopurinol on ischemia/reperfusioninduced liver injury in mice. World J Gastroenterol 14: 2832-2837, 2008..
    • (2008) World J Gastroenterol , vol.14 , pp. 2832-2837
    • Liu, P.G.1    He, S.Q.2    Zhang, Y.H.3    Wu, J.4
  • 105
    • 55849120836 scopus 로고    scopus 로고
    • Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke
    • Liu W, Sood R, Chen Q, Sakoglu U, Hendren J, Cetin O, Miyake M, and Liu KJ. Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke. J Neurochem 107: 1196-1205, 2008..
    • (2008) J Neurochem , vol.107 , pp. 1196-1205
    • Liu, W.1    Sood, R.2    Chen, Q.3    Sakoglu, U.4    Hendren, J.5    Cetin, O.6    Miyake, M.7    Liu, K.J.8
  • 108
    • 0037373455 scopus 로고    scopus 로고
    • Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
    • Marnett LJ, Riggins JN, and West JD. Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J Clin Invest 111: 583-593, 2003..
    • (2003) J Clin Invest , vol.111 , pp. 583-593
    • Marnett, L.J.1    Riggins, J.N.2    West, J.D.3
  • 109
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn KD, Frederick LM, von LK, Dinauer MC, and Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 18: 69-82, 2006..
    • (2006) Cell Signal , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    Von Lk Dinauer, M.C.3    Knaus, U.G.4
  • 110
    • 70349439116 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels
    • Matsuo J, Oku H, Kanbara Y, Kobayashi T, Sugiyama T, and Ikeda T. Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels. Exp Eye Res 89: 693-699, 2009..
    • (2009) Exp Eye Res , vol.89 , pp. 693-699
    • Matsuo, J.1    Oku, H.2    Kanbara, Y.3    Kobayashi, T.4    Sugiyama, T.5    Ikeda, T.6
  • 111
    • 0028847050 scopus 로고
    • Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: Effect of neutrophil depletion on extracellular ascorbyl radical formation
    • Matsuo Y, Kihara T, Ikeda M, Ninomiya M, Onodera H, and Kogure K. Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: effect of neutrophil depletion on extracellular ascorbyl radical formation. J Cereb Blood Flow Metab 15: 941-947, 1995..
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 941-947
    • Matsuo, Y.1    Kihara, T.2    Ikeda, M.3    Ninomiya, M.4    Onodera, H.5    Kogure, K.6
  • 112
    • 49349093647 scopus 로고    scopus 로고
    • Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats
    • McCann SK, Dusting GJ, and Roulston CL. Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats. J Neurosci Res 86: 2524-2534, 2008..
    • (2008) J Neurosci Res , vol.86 , pp. 2524-2534
    • McCann, S.K.1    Dusting, G.J.2    Roulston, C.L.3
  • 113
    • 33947423432 scopus 로고    scopus 로고
    • Duox expression and related H2O2 measurement in mouse thyroid: Onset in embryonic development and regulation by TSH in adult
    • Milenkovic M, De Deken X, Jin L, De Felice M, Di Lauro R, Dumont JE, Corvilain B, and Miot F. Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult. J Endocrinol 192: 615-626, 2007..
    • (2007) J Endocrinol , vol.192 , pp. 615-626
    • Milenkovic, M.1    De Deken, X.2    Jin, L.3    De Felice, M.4    Di Lauro, R.5    Dumont, J.E.6    Corvilain, B.7    Miot, F.8
  • 114
    • 77950241672 scopus 로고    scopus 로고
    • Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia
    • Miller AA, De Silva TM, Judkins CP, Diep H, Drummond GR, and Sobey CG. Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia. Stroke 41: 784-789, 2010..
    • (2010) Stroke , vol.41 , pp. 784-789
    • Miller, A.A.1    De Silva, T.M.2    Judkins, C.P.3    Diep, H.4    Drummond, G.R.5    Sobey, C.G.6
  • 116
    • 34347341696 scopus 로고    scopus 로고
    • Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: Role of estrogen
    • Miller AA, Drummond GR, Mast AE, Schmidt HH, and Sobey CG. Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen. Stroke 38: 2142-2149, 2007..
    • (2007) Stroke , vol.38 , pp. 2142-2149
    • Miller, A.A.1    Drummond, G.R.2    Mast, A.E.3    Schmidt, H.H.4    Sobey, C.G.5
  • 117
    • 27944504319 scopus 로고    scopus 로고
    • NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries
    • Miller AA, Drummond GR, Schmidt HH, and Sobey CG. NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries. Circ Res 97: 1055-1062, 2005..
    • (2005) Circ Res , vol.97 , pp. 1055-1062
    • Miller, A.A.1    Drummond, G.R.2    Schmidt, H.H.3    Sobey, C.G.4
  • 118
    • 33748326080 scopus 로고    scopus 로고
    • NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke
    • Miller AA, Dusting GJ, Roulston CL, and Sobey CG. NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain Res 1111: 111-116, 2006..
    • (2006) Brain Res , vol.1111 , pp. 111-116
    • Miller, A.A.1    Dusting, G.J.2    Roulston, C.L.3    Sobey, C.G.4
  • 119
    • 79952116549 scopus 로고    scopus 로고
    • Reperfusion therapies for acute ischemic stroke: Current pharmacological and mechanical approaches
    • Molina CA. Reperfusion therapies for acute ischemic stroke: current pharmacological and mechanical approaches. Stroke 42: S16-S19, 2011..
    • (2011) Stroke , vol.42
    • Molina, C.A.1
  • 121
    • 77952489013 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells
    • Montezano AC, Burger D, Paravicini TM, Chignalia AZ, Yusuf H, Almasri M, He Y, Callera GE, He G, Krause KH, Lambeth D, Quinn MT, and Touyz RM. Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells. Circ Res 106: 1363-1373, 2010..
    • (2010) Circ Res , vol.106 , pp. 1363-1373
    • Montezano, A.C.1    Burger, D.2    Paravicini, T.M.3    Chignalia, A.Z.4    Yusuf, H.5    Almasri, M.6    He, Y.7    Callera, G.E.8    He, G.9    Krause, K.H.10    Lambeth, D.11    Quinn, M.T.12    Touyz, R.M.13
  • 122
    • 79951857865 scopus 로고    scopus 로고
    • NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion
    • Murotomi K, Takagi N, Takeo S, and Tanonaka K. NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion. Mol Cell Neurosci 46: 681-688, 2011..
    • (2011) Mol Cell Neurosci , vol.46 , pp. 681-688
    • Murotomi, K.1    Takagi, N.2    Takeo, S.3    Tanonaka, K.4
  • 123
    • 79955635908 scopus 로고    scopus 로고
    • NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy
    • Mustapha NM, Tarr JM, Kohner EM, and Chibber R. NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy. J Ophthalmol 2010: 746978, 2010..
    • (2010) J Ophthalmol , vol.2010 , pp. 746978
    • Mustapha, N.M.1    Tarr, J.M.2    Kohner, E.M.3    Chibber, R.4
  • 124
    • 33846194681 scopus 로고    scopus 로고
    • Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat
    • Nagel S, Genius J, Heiland S, Horstmann S, Gardner H, and Wagner S. Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain Res 1132: 210-217, 2007..
    • (2007) Brain Res , vol.1132 , pp. 210-217
    • Nagel, S.1    Genius, J.2    Heiland, S.3    Horstmann, S.4    Gardner, H.5    Wagner, S.6
  • 125
    • 79956347138 scopus 로고    scopus 로고
    • Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea
    • Nair D, Dayyat EA, Zhang SX, Wang Y, and Gozal D. Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea. PLoS One 6: e19847, 2011..
    • (2011) PLoS One , vol.6
    • Nair, D.1    Dayyat, E.A.2    Zhang, S.X.3    Wang, Y.4    Gozal, D.5
  • 128
    • 0842289183 scopus 로고    scopus 로고
    • Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo
    • Paravicini TM, Chrissobolis S, Drummond GR, and Sobey CG. Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke 35: 584-589, 2004..
    • (2004) Stroke , vol.35 , pp. 584-589
    • Paravicini, T.M.1    Chrissobolis, S.2    Drummond, G.R.3    Sobey, C.G.4
  • 129
    • 41149110642 scopus 로고    scopus 로고
    • Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: Role of neuronal NADPH oxidase
    • Park KW and Jin BK. Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: role of neuronal NADPH oxidase. J Neurosci Res 86: 1053-1063, 2008..
    • (2008) J Neurosci Res , vol.86 , pp. 1053-1063
    • Park, K.W.1    Jin, B.K.2
  • 130
    • 14044258771 scopus 로고    scopus 로고
    • NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide
    • Park L, Anrather J, Zhou P, Frys K, Pitstick R, Younkin S, Carlson GA, and Iadecola C. NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide. J Neurosci 25: 1769-1777, 2005..
    • (2005) J Neurosci , vol.25 , pp. 1769-1777
    • Park, L.1    Anrather, J.2    Zhou, P.3    Frys, K.4    Pitstick, R.5    Younkin, S.6    Carlson, G.A.7    Iadecola, C.8
  • 132
    • 78649542708 scopus 로고    scopus 로고
    • Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion
    • Paterniti I, Galuppo M, Mazzon E, Impellizzeri D, Esposito E, Bramanti P, and Cuzzocrea S. Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion. J Leukoc Biol 88: 993-1003, 2010..
    • (2010) J Leukoc Biol , vol.88 , pp. 993-1003
    • Paterniti, I.1    Galuppo, M.2    Mazzon, E.3    Impellizzeri, D.4    Esposito, E.5    Bramanti, P.6    Cuzzocrea, S.7
  • 133
    • 0032772164 scopus 로고    scopus 로고
    • Ischemia-reperfusion lung injury is prevented by apocynin, a novel inhibitor of leukocyte NADPH oxidase
    • Pearse DB and Dodd JM. Ischemia-reperfusion lung injury is prevented by apocynin, a novel inhibitor of leukocyte NADPH oxidase. Chest 116: 55S-56S, 1999..
    • (1999) Chest , vol.116
    • Pearse, D.B.1    Dodd, J.M.2
  • 134
    • 33744949002 scopus 로고    scopus 로고
    • Reactive oxygen species in the neuropathogenesis of hypertension
    • Peterson JR, Sharma RV, and Davisson RL. Reactive oxygen species in the neuropathogenesis of hypertension. Curr Hypertens Rep 8: 232-241, 2006..
    • (2006) Curr Hypertens Rep , vol.8 , pp. 232-241
    • Peterson, J.R.1    Sharma, R.V.2    Davisson, R.L.3
  • 136
    • 49449116792 scopus 로고    scopus 로고
    • Oxidative innate immune defenses by Nox/Duox family NADPH oxidases
    • Rada B and Leto TL. Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contrib Microbiol 15: 164-187, 2008..
    • (2008) Contrib Microbiol , vol.15 , pp. 164-187
    • Rada, B.1    Leto, T.L.2
  • 137
    • 53449086013 scopus 로고    scopus 로고
    • Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2 + ]i through the mitochondrial ROSPKCepsilon signaling axis in pulmonary artery smooth muscle cells
    • Rathore R, Zheng YM, Niu CF, Liu QH, Korde A, Ho YS, and Wang YX. Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2 + ]i through the mitochondrial ROSPKCepsilon signaling axis in pulmonary artery smooth muscle cells. Free Radic Biol Med 45: 1223-1231, 2008..
    • (2008) Free Radic Biol Med , vol.45 , pp. 1223-1231
    • Rathore, R.1    Zheng, Y.M.2    Niu, C.F.3    Liu, Q.H.4    Korde, A.5    Ho, Y.S.6    Wang, Y.X.7
  • 139
    • 77958555016 scopus 로고    scopus 로고
    • Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat
    • Raz L, Zhang QG, Zhou CF, Han D, Gulati P, Yang LC, Yang F, Wang RM, and Brann DW. Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat. PLoS One 5: e12606, 2010..
    • (2010) PLoS One , vol.5
    • Raz, L.1    Zhang, Q.G.2    Zhou, C.F.3    Han, D.4    Gulati, P.5    Yang, L.C.6    Yang, F.7    Wang, R.M.8    Brann, D.W.9
  • 140
    • 34247547012 scopus 로고    scopus 로고
    • Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices
    • Reinehr R, Gorg B, Becker S, Qvartskhava N, Bidmon HJ, Selbach O, Haas HL, Schliess F, and Haussinger D. Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices. Glia 55: 758-771, 2007..
    • (2007) Glia , vol.55 , pp. 758-771
    • Reinehr, R.1    Gorg, B.2    Becker, S.3    Qvartskhava, N.4    Bidmon, H.J.5    Selbach, O.6    Haas, H.L.7    Schliess, F.8    Haussinger, D.9
  • 141
    • 33947511484 scopus 로고    scopus 로고
    • The impact of recanalization on ischemic stroke outcome: A meta-analysis
    • Rha JH and Saver JL. The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 38: 967-973, 2007..
    • (2007) Stroke , vol.38 , pp. 967-973
    • Rha, J.H.1    Saver, J.L.2
  • 142
    • 33646130154 scopus 로고    scopus 로고
    • The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress
    • Riganti C, Costamagna C, Bosia A, and Ghigo D. The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress. Toxicol Appl Pharmacol 212: 179-187, 2006..
    • (2006) Toxicol Appl Pharmacol , vol.212 , pp. 179-187
    • Riganti, C.1    Costamagna, C.2    Bosia, A.3    Ghigo, D.4
  • 143
    • 3142514201 scopus 로고    scopus 로고
    • Protein aggregation and neurodegenerative disease
    • Ross CA and Poirier MA. Protein aggregation and neurodegenerative disease. Nat Med 10 Suppl: S10-S17, 2004..
    • (2004) Nat Med , vol.10 , Issue.SUPPL.
    • Ross, C.A.1    Poirier, M.A.2
  • 144
    • 78649887721 scopus 로고    scopus 로고
    • Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: Therapeutic implications
    • Saavedra JM, Sanchez-Lemus E, and Benicky J. Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: therapeutic implications. Psychoneuroendocrinology 36: 1-18, 2011..
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 1-18
    • Saavedra, J.M.1    Sanchez-Lemus, E.2    Benicky, J.3
  • 146
    • 0142030521 scopus 로고    scopus 로고
    • To what end does nature produce superoxide? NADPH oxidase as an autocrine modifier of membrane phospholipids generating paracrine lipid messengers
    • Saran M. To what end does nature produce superoxide? NADPH oxidase as an autocrine modifier of membrane phospholipids generating paracrine lipid messengers. Free Radic Res 37: 1045-1059, 2003..
    • (2003) Free Radic Res , vol.37 , pp. 1045-1059
    • Saran, M.1
  • 150
    • 34548791801 scopus 로고    scopus 로고
    • Rhokinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: Effect on hepatocellular NADPH oxidase system
    • Shiotani S, Shimada M, Taketomi A, Soejima Y, Yoshizumi T, Hashimoto K, Shimokawa H, and Maehara Y. Rhokinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: effect on hepatocellular NADPH oxidase system. Gene Ther 14: 1425-1433, 2007..
    • (2007) Gene Ther , vol.14 , pp. 1425-1433
    • Shiotani, S.1    Shimada, M.2    Taketomi, A.3    Soejima, Y.4    Yoshizumi, T.5    Hashimoto, K.6    Shimokawa, H.7    Maehara, Y.8
  • 153
    • 67651184281 scopus 로고    scopus 로고
    • NOX enzymes in the central nervous system: From signaling to disease
    • Sorce S and Krause KH. NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal 11: 2481-2504, 2009..
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2481-2504
    • Sorce, S.1    Krause, K.H.2
  • 156
    • 0028473441 scopus 로고
    • Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol
    • Stolk J, Hiltermann TJ, Dijkman JH, and Verhoeven AJ. Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. Am J Respir Cell Mol Biol 11: 95-102, 1994..
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 95-102
    • Stolk, J.1    Hiltermann, T.J.2    Dijkman, J.H.3    Verhoeven, A.J.4
  • 159
    • 33846426432 scopus 로고    scopus 로고
    • Cyclic stretch-induced reactive oxygen species generation enhances apoptosis in retinal pericytes through c-jun NH2-terminal kinase activation
    • Suzuma I, Murakami T, Suzuma K, Kaneto H, Watanabe D, Ojima T, Honda Y, Takagi H, and Yoshimura N. Cyclic stretch-induced reactive oxygen species generation enhances apoptosis in retinal pericytes through c-jun NH2-terminal kinase activation. Hypertension 49: 347-354, 2007..
    • (2007) Hypertension , vol.49 , pp. 347-354
    • Suzuma, I.1    Murakami, T.2    Suzuma, K.3    Kaneto, H.4    Watanabe, D.5    Ojima, T.6    Honda, Y.7    Takagi, H.8    Yoshimura, N.9
  • 161
    • 34547858520 scopus 로고    scopus 로고
    • Apocynin attenuates cerebral infarction after transient focal ischaemia in rats
    • Tang LL, Ye K, Yang XF, and Zheng JS. Apocynin attenuates cerebral infarction after transient focal ischaemia in rats. J Int Med Res 35: 517-522, 2007..
    • (2007) J Int Med Res , vol.35 , pp. 517-522
    • Tang, L.L.1    Ye, K.2    Yang, X.F.3    Zheng, J.S.4
  • 162
    • 46549086942 scopus 로고    scopus 로고
    • Apocynin improves outcome in experimental stroke with a narrow dose range
    • Tang XN, Cairns B, Cairns N, and Yenari MA. Apocynin improves outcome in experimental stroke with a narrow dose range. Neuroscience 154: 556-562, 2008..
    • (2008) Neuroscience , vol.154 , pp. 556-562
    • Tang, X.N.1    Cairns, B.2    Cairns, N.3    Yenari, M.A.4
  • 163
    • 84855360910 scopus 로고    scopus 로고
    • Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke
    • Tang XN, Zheng Z, Giffard RG, and Yenari MA. Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke. Ann Neurol 70: 606-615, 2011..
    • (2011) Ann Neurol , vol.70 , pp. 606-615
    • Tang, X.N.1    Zheng, Z.2    Giffard, R.G.3    Yenari, M.A.4
  • 165
    • 0026008909 scopus 로고
    • Oxygen radical mechanisms of brain injury following ischemia and reperfusion
    • Traystman RJ, Kirsch JR, and Koehler RC. Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J Appl Physiol 71: 1185-1195, 1991..
    • (1991) J Appl Physiol , vol.71 , pp. 1185-1195
    • Traystman, R.J.1    Kirsch, J.R.2    Koehler, R.C.3
  • 166
    • 33746191327 scopus 로고    scopus 로고
    • Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion
    • Trinkl A, Vosko MR, Wunderlich N, Dichgans M, and Hamann GF. Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion. Eur J Neurosci 24: 520-526, 2006..
    • (2006) Eur J Neurosci , vol.24 , pp. 520-526
    • Trinkl, A.1    Vosko, M.R.2    Wunderlich, N.3    Dichgans, M.4    Hamann, G.F.5
  • 168
    • 0035930856 scopus 로고    scopus 로고
    • Effects of methoxylation of apocynin and analogs on the inhibition of reactive oxygen species production by stimulated human neutrophils
    • Van den Worm E, Beukelman CJ, Van den Berg AJ, Kroes BH, Labadie RP, and Van Dijk H. Effects of methoxylation of apocynin and analogs on the inhibition of reactive oxygen species production by stimulated human neutrophils. Eur J Pharmacol 433: 225-230, 2001..
    • (2001) Eur J Pharmacol , vol.433 , pp. 225-230
    • Van Den Worm, E.1    Beukelman, C.J.2    Van Den Berg, A.J.3    Kroes, B.H.4    Labadie, R.P.5    Van Dijk, H.6
  • 169
    • 0037178764 scopus 로고    scopus 로고
    • Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice
    • Vecchione C and Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice. Circ Res 91: 173-179, 2002..
    • (2002) Circ Res , vol.91 , pp. 173-179
    • Vecchione, C.1    Brandes, R.P.2
  • 170
    • 14544290505 scopus 로고    scopus 로고
    • Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells
    • Vejrazka M, Micek R, and Stipek S. Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells. Biochim Biophys Acta 1722: 143-147, 2005..
    • (2005) Biochim Biophys Acta , vol.1722 , pp. 143-147
    • Vejrazka, M.1    Micek, R.2    Stipek, S.3
  • 173
    • 34548126863 scopus 로고    scopus 로고
    • Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: Role of NADPH oxidase-derived ROS
    • Wang Q, Sun AY, Simonyi A, Kalogeris TJ, Miller DK, Sun GY, and Korthuis RJ. Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: role of NADPH oxidase-derived ROS. Free Radic Biol Med 43: 1048-1060, 2007..
    • (2007) Free Radic Biol Med , vol.43 , pp. 1048-1060
    • Wang, Q.1    Sun, A.Y.2    Simonyi, A.3    Kalogeris, T.J.4    Miller, D.K.5    Sun, G.Y.6    Korthuis, R.J.7
  • 178
    • 3042782805 scopus 로고    scopus 로고
    • Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder
    • Woo TU, Walsh JP, and Benes FM. Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry 61: 649-657, 2004..
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 649-657
    • Woo, T.U.1    Walsh, J.P.2    Benes, F.M.3
  • 179
    • 65349088460 scopus 로고    scopus 로고
    • Cross-talk between mitochondria and NADPH oxidase: Effects of mild mitochondrial dysfunction on angiotensin IImediated increase in Nox isoform expression and activity in vascular smooth muscle cells
    • Wosniak J, Jr., Santos CX, Kowaltowski AJ, and Laurindo FR. Cross-talk between mitochondria and NADPH oxidase: effects of mild mitochondrial dysfunction on angiotensin IImediated increase in Nox isoform expression and activity in vascular smooth muscle cells. Antioxid Redox Signal 11: 1265-1278, 2009..
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1265-1278
    • Wosniak Jr., J.1    Santos, C.X.2    Kowaltowski, A.J.3    Laurindo, F.R.4
  • 180
    • 61549089327 scopus 로고    scopus 로고
    • NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury
    • Yang Z, Sharma AK, Marshall M, Kron IL, and Laubach VE. NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury. Am J Respir Cell Mol Biol 40: 375-381, 2009..
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 375-381
    • Yang, Z.1    Sharma, A.K.2    Marshall, M.3    Kron, I.L.4    Laubach, V.E.5
  • 181
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, and Dalkara T. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med 15: 1031-1037, 2009..
    • (2009) Nat Med , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3    Can, A.4    Topalkara, K.5    Dalkara, T.6
  • 184
    • 79960697192 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia
    • Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, and Prabhakar NR. Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol 226: 2925-2933, 2011..
    • (2011) J Cell Physiol , vol.226 , pp. 2925-2933
    • Yuan, G.1    Khan, S.A.2    Luo, W.3    Nanduri, J.4    Semenza, G.L.5    Prabhakar, N.R.6
  • 187
    • 0029096735 scopus 로고
    • Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat
    • Zhang RL, Chopp M, Jiang N, Tang WX, Prostak J, Manning AM, and Anderson DC. Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat. Stroke 26: 1438-1442, 1995..
    • (1995) Stroke , vol.26 , pp. 1438-1442
    • Zhang, R.L.1    Chopp, M.2    Jiang, N.3    Tang, W.X.4    Prostak, J.5    Manning, A.M.6    Anderson, D.C.7
  • 188
    • 78049287232 scopus 로고    scopus 로고
    • Alcohol-induced exacerbation of ischemic brain injury: Role of NAD(P)H oxidase
    • Zhao H, Mayhan WG, Arrick DM, Xiong W, and Sun H. Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase. Alcohol Clin Exp Res 34: 1948-1955, 2010..
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 1948-1955
    • Zhao, H.1    Mayhan, W.G.2    Arrick, D.M.3    Xiong, W.4    Sun, H.5
  • 189
    • 15744405782 scopus 로고    scopus 로고
    • Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells
    • Zimmerman MC, Sharma RV, and Davisson RL. Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells. Hypertension 45: 717-723, 2005..
    • (2005) Hypertension , vol.45 , pp. 717-723
    • Zimmerman, M.C.1    Sharma, R.V.2    Davisson, R.L.3


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