-
1
-
-
84859726398
-
Platelets: Versatile effector cells in hemostasis, inflammation, and the immune continuum
-
Vieira-de-Abreu A, Campbell RA, Weyrich AS, Zimmerman GA. Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum. Semin Immunopathol. 2012;34(1):5-30.
-
(2012)
Semin Immunopathol
, vol.34
, Issue.1
, pp. 5-30
-
-
Vieira-De-Abreu, A.1
Campbell, R.A.2
Weyrich, A.S.3
Zimmerman, G.A.4
-
2
-
-
77955047782
-
GPVI and CLEC-2 in hemostasis and vascular integrity
-
Watson SP, Herbert JM, Pollitt AY. GPVI and CLEC-2 in hemostasis and vascular integrity. J Thromb Haemost. 2010;8(7): 1456-1467.
-
(2010)
J Thromb Haemost
, vol.8
, Issue.7
, pp. 1456-1467
-
-
Watson, S.P.1
Herbert, J.M.2
Pollitt, A.Y.3
-
3
-
-
84959159289
-
Platelet immunoreceptor tyrosine-based activation motif (ITAM) and hemITAM signaling and vascular integrity in inflammation and development
-
Lee RH, Bergmeier W. Platelet immunoreceptor tyrosine-based activation motif (ITAM) and hemITAM signaling and vascular integrity in inflammation and development. J Thromb Haemost. 2016;14(4):645-654.
-
(2016)
J Thromb Haemost
, vol.14
, Issue.4
, pp. 645-654
-
-
Lee, R.H.1
Bergmeier, W.2
-
4
-
-
84867888747
-
Platelet GPVI: A target for antithrombotic therapy?!
-
Dütting S, Bender M, Nieswandt B. Platelet GPVI: a target for antithrombotic therapy?! Trends Pharmacol Sci. 2012;33(11): 583-590.
-
(2012)
Trends Pharmacol Sci
, vol.33
, Issue.11
, pp. 583-590
-
-
Dütting, S.1
Bender, M.2
Nieswandt, B.3
-
5
-
-
32644435352
-
Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI
-
Inoue O, Suzuki-Inoue K, McCarty OJ, et al. Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. Blood. 2006;107(4): 1405-1412.
-
(2006)
Blood
, vol.107
, Issue.4
, pp. 1405-1412
-
-
Inoue, O.1
Suzuki-Inoue, K.2
McCarty, O.J.3
-
6
-
-
84881093501
-
Integrin a6b1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis
-
Schaff M, Tang C, Maurer E, et al. Integrin a6b1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis. Circulation. 2013;128(5):541-552.
-
(2013)
Circulation
, vol.128
, Issue.5
, pp. 541-552
-
-
Schaff, M.1
Tang, C.2
Maurer, E.3
-
7
-
-
43749115532
-
Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex
-
Riba R, Hughes CE, Graham A, Watson SP, Naseem KM. Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex. J Thromb Haemost. 2008;6(6): 1012-1020.
-
(2008)
J Thromb Haemost
, vol.6
, Issue.6
, pp. 1012-1020
-
-
Riba, R.1
Hughes, C.E.2
Graham, A.3
Watson, S.P.4
Naseem, K.M.5
-
8
-
-
84942279085
-
Fibrin activates GPVI in human and mouse platelets
-
Alshehri OM, Hughes CE, Montague S, et al. Fibrin activates GPVI in human and mouse platelets. Blood. 2015;126(13):1601-1608.
-
(2015)
Blood
, vol.126
, Issue.13
, pp. 1601-1608
-
-
Alshehri, O.M.1
Hughes, C.E.2
Montague, S.3
-
9
-
-
84935025237
-
Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands
-
Alshehri OM, Montague S, Watson S, et al. Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochem J. 2015;468(3):459-473.
-
(2015)
Biochem J
, vol.468
, Issue.3
, pp. 459-473
-
-
Alshehri, O.M.1
Montague, S.2
Watson, S.3
-
10
-
-
84878642457
-
The physiological and pathophysiological roles of platelet CLEC-2
-
Navarro-Núñez L, Langan SA, Nash GB, Watson SP. The physiological and pathophysiological roles of platelet CLEC-2. Thromb Haemost. 2013;109(6): 991-998.
-
(2013)
Thromb Haemost
, vol.109
, Issue.6
, pp. 991-998
-
-
Navarro-Núñez, L.1
Langan, S.A.2
Nash, G.B.3
Watson, S.P.4
-
11
-
-
84940063259
-
Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice
-
Gros A, Syvannarath V, Lamrani L, et al. Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice. Blood. 2015; 126(8):1017-1026.
-
(2015)
Blood
, vol.126
, Issue.8
, pp. 1017-1026
-
-
Gros, A.1
Syvannarath, V.2
Lamrani, L.3
-
12
-
-
84873377815
-
Platelet ITAM signaling is critical for vascular integrity in inflammation
-
Boulaftali Y, Hess PR, Getz TM, et al. Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest. 2013;123(2): 908-916.
-
(2013)
J Clin Invest
, vol.123
, Issue.2
, pp. 908-916
-
-
Boulaftali, Y.1
Hess, P.R.2
Getz, T.M.3
-
13
-
-
84919621107
-
Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice
-
de Stoppelaar SF, van’t Veer C, Claushuis TAM, Albersen BJA, Roelofs JJTH, van der Poll T. Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice. Blood. 2014;124(25): 3781-3790.
-
(2014)
Blood
, vol.124
, Issue.25
, pp. 3781-3790
-
-
de Stoppelaar, S.F.1
van’t Veer, C.2
Claushuis, T.A.M.3
Albersen, B.J.A.4
Roelofs, J.J.T.H.5
van der Poll, T.6
-
14
-
-
84924330133
-
Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia
-
van den Boogaard FE, Schouten M, de Stoppelaar SF, et al. Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia. Crit Care Med. 2015;43(3):e75-e83.
-
(2015)
Crit Care Med
, vol.43
, Issue.3
, pp. e75-e83
-
-
van den Boogaard, F.E.1
Schouten, M.2
de Stoppelaar, S.F.3
-
15
-
-
34147188469
-
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
-
Clark SR, Ma AC, Tavener SA, et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med. 2007;13(4):463-469.
-
(2007)
Nat Med
, vol.13
, Issue.4
, pp. 463-469
-
-
Clark, S.R.1
Ma, A.C.2
Tavener, S.A.3
-
16
-
-
84866386143
-
Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis
-
McDonald B, Urrutia R, Yipp BG, Jenne CN, Kubes P. Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. Cell Host Microbe. 2012;12(3): 324-333.
-
(2012)
Cell Host Microbe
, vol.12
, Issue.3
, pp. 324-333
-
-
McDonald, B.1
Urrutia, R.2
Yipp, B.G.3
Jenne, C.N.4
Kubes, P.5
-
17
-
-
84899623562
-
Platelet glycoprotein Ib-IX as a regulator of systemic inflammation
-
Corken A, Russell S, Dent J, Post SR, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014;34(5):996-1001.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, Issue.5
, pp. 996-1001
-
-
Corken, A.1
Russell, S.2
Dent, J.3
Post, S.R.4
Ware, J.5
-
18
-
-
84940899801
-
The role of platelet MyD88 in host response during gram-negative sepsis
-
de Stoppelaar SF, Claushuis TA, Jansen MP, et al. The role of platelet MyD88 in host response during gram-negative sepsis. J Thromb Haemost. 2015;13(9): 1709-1720.
-
(2015)
J Thromb Haemost
, vol.13
, Issue.9
, pp. 1709-1720
-
-
de Stoppelaar, S.F.1
Claushuis, T.A.2
Jansen, M.P.3
-
19
-
-
84930180527
-
Platelet and endothelial cell P-selectin are required for host defense against Klebsiella pneumoniae-induced pneumosepsis
-
de Stoppelaar SF, Van’t Veer C, Roelofs JJ, et al. Platelet and endothelial cell P-selectin are required for host defense against Klebsiella pneumoniae-induced pneumosepsis. J Thromb Haemost. 2015;13(6): 1128-1138.
-
(2015)
J Thromb Haemost
, vol.13
, Issue.6
, pp. 1128-1138
-
-
de Stoppelaar, S.F.1
Van’t Veer, C.2
Roelofs, J.J.3
-
20
-
-
34547134973
-
Diverging signaling events control the pathway of GPVI down-regulation in vivo
-
Rabie T, Varga-Szabo D, Bender M, et al. Diverging signaling events control the pathway of GPVI down-regulation in vivo. Blood. 2007;110(2):529-535.
-
(2007)
Blood
, vol.110
, Issue.2
, pp. 529-535
-
-
Rabie, T.1
Varga-Szabo, D.2
Bender, M.3
-
21
-
-
70350111448
-
CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis
-
May F, Hagedorn I, Pleines I, et al. CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis. Blood. 2009; 114(16):3464-3472.
-
(2009)
Blood
, vol.114
, Issue.16
, pp. 3464-3472
-
-
May, F.1
Hagedorn, I.2
Pleines, I.3
-
22
-
-
84907056409
-
Protease-activated receptor-2 deficient mice have reduced house dust mite-evoked allergic lung inflammation
-
de Boer JD, Van’t Veer C, Stroo I, et al. Protease-activated receptor-2 deficient mice have reduced house dust mite-evoked allergic lung inflammation. Innate Immun. 2014;20(6): 618-625.
-
(2014)
Innate Immun
, vol.20
, Issue.6
, pp. 618-625
-
-
de Boer, J.D.1
Van’t Veer, C.2
Stroo, I.3
-
23
-
-
84948843996
-
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets
-
Hitchcock JR, Cook CN, Bobat S, et al. Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets. J Clin Invest. 2015;125(12):4429-4446.
-
(2015)
J Clin Invest
, vol.125
, Issue.12
, pp. 4429-4446
-
-
Hitchcock, J.R.1
Cook, C.N.2
Bobat, S.3
-
24
-
-
85013278353
-
Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions
-
Claushuis TA, de Stoppelaar SF, Stroo I, et al. Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions. J Thromb Haemost. 2017;15(4): 744-757.
-
(2017)
J Thromb Haemost
, vol.15
, Issue.4
, pp. 744-757
-
-
Claushuis, T.A.1
de Stoppelaar, S.F.2
Stroo, I.3
-
25
-
-
0035910757
-
Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice
-
Nieswandt B, Schulte V, Bergmeier W, et al. Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice. J Exp Med. 2001;193(4):459-469.
-
(2001)
J Exp Med
, vol.193
, Issue.4
, pp. 459-469
-
-
Nieswandt, B.1
Schulte, V.2
Bergmeier, W.3
-
26
-
-
84871505285
-
Thrombosis as an intravascular effector of innate immunity
-
Engelmann B, Massberg S. Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol. 2013;13(1):34-45.
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.1
, pp. 34-45
-
-
Engelmann, B.1
Massberg, S.2
-
27
-
-
0032933183
-
Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of single, collagen-adherent platelets
-
Heemskerk JW, Siljander P, Vuist WM, et al. Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of single, collagen-adherent platelets. Thromb Haemost. 1999;81(5):782-792.
-
(1999)
Thromb Haemost
, vol.81
, Issue.5
, pp. 782-792
-
-
Heemskerk, J.W.1
Siljander, P.2
Vuist, W.M.3
-
28
-
-
84979986145
-
Oral administration of Bruton’s tyrosine kinase inhibitors impairs GPVI-mediated platelet function
-
Rigg RA, Aslan JE, Healy LD, et al. Oral administration of Bruton’s tyrosine kinase inhibitors impairs GPVI-mediated platelet function. Am J Physiol Cell Physiol. 2016; 310(5):C373-C380.
-
(2016)
Am J Physiol Cell Physiol
, vol.310
, Issue.5
, pp. C373-C380
-
-
Rigg, R.A.1
Aslan, J.E.2
Healy, L.D.3
-
29
-
-
1542755135
-
Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments
-
Lecut C, Feeney LA, Kingsbury G, et al. Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments. J Thromb Haemost. 2003; 1(12):2653-2662.
-
(2003)
J Thromb Haemost
, vol.1
, Issue.12
, pp. 2653-2662
-
-
Lecut, C.1
Feeney, L.A.2
Kingsbury, G.3
-
30
-
-
44949114152
-
Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity
-
Chackalamannil S, Wang Y, Greenlee WJ, et al. Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity. J Med Chem. 2008; 51(11):3061-3064.
-
(2008)
J Med Chem
, vol.51
, Issue.11
, pp. 3061-3064
-
-
Chackalamannil, S.1
Wang, Y.2
Greenlee, W.J.3
-
31
-
-
46749098410
-
Inflammation induces hemorrhage in thrombocytopenia
-
Goerge T, Ho-Tin-Noe B, Carbo C, et al. Inflammation induces hemorrhage in thrombocytopenia. Blood. 2008;111(10): 4958-4964.
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 4958-4964
-
-
Goerge, T.1
Ho-Tin-Noe, B.2
Carbo, C.3
-
32
-
-
84945491738
-
Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia
-
Hillgruber C, Pöppelmann B, Weishaupt C, et al. Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia. J Exp Med. 2015;212(8):1255-1266.
-
(2015)
J Exp Med
, vol.212
, Issue.8
, pp. 1255-1266
-
-
Hillgruber, C.1
Pöppelmann, B.2
Weishaupt, C.3
-
33
-
-
85007357743
-
Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation
-
Cortjens B, Lutter R, Boon L, Bem RA, van Woensel JB. Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation. PLoS One. 2016;11(12): e0168779.
-
(2016)
PLoS One
, vol.11
, Issue.12
, pp. e0168779
-
-
Cortjens, B.1
Lutter, R.2
Boon, L.3
Bem, R.A.4
van Woensel, J.B.5
-
34
-
-
77956510719
-
Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway
-
Devi S, Kuligowski MP, Kwan RY, et al. Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway. Am J Pathol. 2010;177(3): 1131-1142.
-
(2010)
Am J Pathol
, vol.177
, Issue.3
, pp. 1131-1142
-
-
Devi, S.1
Kuligowski, M.P.2
Kwan, R.Y.3
-
35
-
-
84889570738
-
Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway
-
Xiang B, Zhang G, Guo L, et al. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun. 2013;4:2657.
-
(2013)
Nat Commun.
, vol.4
, pp. 2657
-
-
Xiang, B.1
Zhang, G.2
Guo, L.3
-
36
-
-
84885460302
-
Activated platelets enhance IL-10 secretion and reduce TNF-a secretion by monocytes
-
Gudbrandsdottir S, Hasselbalch HC, Nielsen CH. Activated platelets enhance IL-10 secretion and reduce TNF-a secretion by monocytes. J Immunol. 2013;191(8): 4059-4067.
-
(2013)
J Immunol
, vol.191
, Issue.8
, pp. 4059-4067
-
-
Gudbrandsdottir, S.1
Hasselbalch, H.C.2
Nielsen, C.H.3
-
37
-
-
85013962639
-
GPVI and thromboxane receptor on platelets promote proinflammatory macrophage phenotypes during cutaneous inflammation
-
Pierre S, Linke B, Suo J, et al. GPVI and thromboxane receptor on platelets promote proinflammatory macrophage phenotypes during cutaneous inflammation. J Invest Dermatol. 2017;137(3): 686-695.
-
(2017)
J Invest Dermatol
, vol.137
, Issue.3
, pp. 686-695
-
-
Pierre, S.1
Linke, B.2
Suo, J.3
-
38
-
-
84881012996
-
Superactivated platelets: Thrombus regulators, thrombin generators, and potential clinical targets
-
Mazepa M, Hoffman M, Monroe D. Superactivated platelets: thrombus regulators, thrombin generators, and potential clinical targets. Arterioscler Thromb Vasc Biol. 2013;33(8):1747-1752.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, Issue.8
, pp. 1747-1752
-
-
Mazepa, M.1
Hoffman, M.2
Monroe, D.3
|