Structural basis for the inhibition of host gene expression by porcine epidemic diarrhea virus nsp1

Journal of Virology

Volumn 92, Issue 5, 2018, Pages

  Shen, Zhou ^a   Ye, Gang ^a   Deng, Feng ^a   Wang, Gang ^a   Cui, Min ^a   Fang, Liurong ^a   Xiao, Shaobo ^a   Fu, Zhen F ^a,b   Peng, Guiqing ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

C terminus; Host gene expression inhibition; Nonstructural protein 1; Porcine epidemic diarrhea virus; Structure

Indexed keywords

NONSTRUCTURAL PROTEIN 1; LIVE VACCINE; NSP1 PROTEIN, SARS CORONAVIRUS; RNA DIRECTED RNA POLYMERASE; VIRAL PROTEIN;

ALPHA HELIX; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE EXPRESSION; INHIBITION KINETICS; LUCIFERASE ASSAY; NONHUMAN; PORCINE EPIDEMIC DIARRHEA VIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CLASSIFICATION; CORONAVIRINAE; CORONAVIRUS INFECTION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; MOLECULAR MODEL; PHYSIOLOGY; PIG; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; SARS CORONAVIRUS; SEQUENCE ALIGNMENT; SWINE DISEASE; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIROLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CORONAVIRUS; CORONAVIRUS INFECTIONS; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION REGULATION; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, MOLECULAR; PORCINE EPIDEMIC DIARRHEA VIRUS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RNA REPLICASE; SARS VIRUS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SWINE; SWINE DISEASES; TRANSMISSIBLE GASTROENTERITIS VIRUS; VACCINES, ATTENUATED; VIRAL NONSTRUCTURAL PROTEINS;

EID: 85042032266     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01896-17     Document Type: Article

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