Biochemical and structural insights into the mechanisms of sars coronavirus RNA ribose 2′-O-methylation by nsp16/nsp10 protein complex

PLoS Pathogens

Volumn 7, Issue 10, 2011, Pages

  Chen, Yu ^a   Su, Ceyang ^a   Ke, Min ^a   Jin, Xu ^a   Xu, Lirong ^a   Zhang, Zhou ^a   Wu, Andong ^a   Sun, Ying ^a   Yang, Zhouning ^a   Tien, Po ^a   Ahola, Tero ^b   Liang, Yi ^a   Liu, Xinqi ^c   Guo, Deyin ^a,d  

^a WUHAN UNIVERSITY   (China)

^b UNIVERSITY OF HELSINKI   (Finland)

^c NANKAI UNIVERSITY   (China)

^d WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE; NONSTRUCTURAL PROTEIN 10; NONSTRUCTURAL PROTEIN 16; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; CAPPED RNA; M7GPPPA; NSP10 PROTEIN, SARS VIRUS; NSP16 PROTEIN, SARS VIRUS; S ADENOSYL L METHIONINE DEPENDENT N METHYLTRANSFERASE; S-ADENOSYL-L-METHIONINE-DEPENDENT N-METHYLTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; NONHUMAN; PROTEIN FUNCTION; PROTEIN METHYLATION; RNA BINDING; SARS CORONAVIRUS; VIRUS MORPHOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; METHYLATION; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CORONAVIRUS; EUKARYOTA; SARS CORONAVIRUS;

CRYSTALLOGRAPHY, X-RAY; METHYLATION; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RNA CAP ANALOGS; RNA CAPS; RNA, VIRAL; S-ADENOSYLMETHIONINE; SARS VIRUS; VIRAL NONSTRUCTURAL PROTEINS;

EID: 80055066817     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002294     Document Type: Article

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